Detection of aneuploidy and aneuploidy-inducing agents in human lymphocytes using fluorescence in situ hybridization with chromosome-specific DNA probes

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

The chromosomes in human cancer and leukemia

1990 • 1,780 citations

Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

1988 • 1,334 citations

The Chromosomal Basis of Human Neoplasia

1983 • 1,121 citations

The Chromosomes in Human Cancer and Leukemia

1981 • 934 citations

Identification of aneuploidy‐inducing agents using cytokinesis‐blocked human lymphocytes and an antikinetochore antibody

1989 • 645 citations

Hierarchical order in chromosome-specific human alpha satellite DNA

1987 • 510 citations

Cloning of human satellite III DNA: different components are on different chromosomes

1979 • 470 citations

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84

1986 • 380 citations

Human chromosome-specific repetitive DNA sequences: novel markers for genetic analysis

1987 • 271 citations

Chemically induced aneuploidy in mammalian cells: Mechanisms and biological significance in cancer

1986 • 260 citations

The DNA content of micronuclei induced in mouse bone marrow by γ-irradiation: evidence that micronuclei arise from acentric chromosomal fragments

1977 • 245 citations

Structure, Organization, and Sequence of Alpha Satellite DNA from Human Chromosome 17: Evidence for Evolution by Unequal Crossing-Over and an Ancestral Pentamer Repeat Shared With the Human X Chromosome

1986 • 238 citations

Genomic Organization of Alpha Satellite DNA on Human Chromosome 7: Evidence for Two Distinct Alphoid Domains on a Single Chromosome

1987 • 231 citations

Detection of chromosome aneuploidy in interphase nuclei from human primary breast tumors using chromosome-specific repetitive DNA probes.

1988 • 231 citations

Chromosome-specific alpha satellite DNA: nucleotide sequence analysis of the 2.0 kilobasepair repeat from the human X chromosome

1985 • 188 citations

Chromosomes in solid tumors and beyond.

1988 • 185 citations

Rapid interphase and metaphase assessment of specific chromosomal changes in neuroectodermal tumor cells by in situ hybridization with chemically modified DNA probes

1988 • 177 citations

Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss

1989 • 172 citations

EFFECTS OF MITOMYCIN C ON HUMAN CHROMOSOMES

1964 • 171 citations

Structure, organization, and sequence of alpha satellite DNA from human chromosome 17: evidence for evolution by unequal crossing-over and an ancestral pentamer repeat shared with the human X chromosome.

1986 • 150 citations

Genomic organization of alpha satellite DNA on human chromosome 7: evidence for two distinct alphoid domains on a single chromosome.

1987 • 149 citations

Chromosome error propagation and cancer

1989 • 114 citations

Aneuploidy. Part A: Incidence and etiology.

1987 • 101 citations

Fluorescence in situ hybridization to interphase cell nuclei in suspension allows flow cytometric analysis of chromosome content and microscopic analysis of nuclear organization

1988 • 95 citations

Mutations in human lymphocytes commonly involve gene duplication and resemble those seen in cancer cels.

1988 • 62 citations

Current status of cytogenetic studies in animal tumors with special reference to nonrandom chromosome changes

1982 • 53 citations

Banding technique used for the detection of chromosomal aberrations induced by radiation and alkylating agents TEPA and epichlorohydrin

1976 • 51 citations

Nonrandom distribution of chromosomal aberrations induced by three chemicals

1979 • 50 citations

Aneuploidy in mammalian somatic cells in vivo

1986 • 50 citations

The chemotherapeutic drug melphalan induces breakage of chromosomes regions rearranged in secondary leukemia

1989 • 40 citations

Preferential location of chlorambucil-induced breakage in the chromosomes of normal human lymphocytes

1974 • 39 citations

Localization of γ-rays induced chromatid breaks using a three consecutive staining-technique

1978 • 39 citations

The effects of busulphan on the chromosomes of normal human lymphocytes

1978 • 39 citations

Organization and chromosomal specificity of autosomal homologs of human Y chromosome repeated DNA

1985 • 38 citations

Role of chromosome loss in ras/myc-induced Syrian hamster tumors.

1988 • 35 citations

Aneuploidy assays on interphase nuclei by means of in situ hybridization with DNA probes

1989 • 34 citations

Chromosome aberrations induced in vitro by low doses of radiation: nondisjunction in lymphocytes of young adults.

1975 • 31 citations

Chromosomes and Cancer in the Mouse: Studies in Tumors, Established Cell Lines, and Cell Hybrids

1983 • 30 citations

Double Y as an indicator in a test of mitotic non-disjunction in cultured human lymphocytes

1983 • 28 citations

The effects of busulphan on the chromosomes of normal human lymphocytes

1978 • 28 citations

The observation of mitotic division aberrations in mammalian cells exposed to chemical and radiation treatments

1985 • 25 citations