ATP Binding and Hydrolysis by the Multifunctional Protein Disulfide Isomerase

Protein folding in the cell

1992 • 4,138 citations

Protein disulphide isomerase: building bridges in protein folding

1994 • 718 citations

Kinetics of Molecular Chaperone Action

1994 • 440 citations

Catalysis of the oxidative folding of ribonuclease A by protein disulfide isomerase: dependence of the rate on the composition of the redox buffer

1991 • 408 citations

The Role of ATP in the Functional Cycle of the DnaK Chaperone System

1995 • 388 citations

ATP-induced protein Hsp70 complex dissociation requires K+ but not ATP hydrolysis

1993 • 366 citations

Protein disulfide isomerase. A multifunctional protein resident in the lumen of the endoplasmic reticulum.

1992 • 318 citations

Role of ATP and disulphide bonds during protein folding in the endoplasmic reticulum

1992 • 286 citations

A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes Ca(2+)-binding proteins and members of the thioredoxin superfamily.

1994 • 279 citations

Chaperone-like activity of protein disulfide isomerase in the refolding of a protein with no disulfide bonds.

1994 • 268 citations

Protein disulfide isomerase exhibits chaperone and anti-chaperone activity in the oxidative refolding of lysozyme.

1994 • 267 citations

The essential function of yeast protein disulfide isomerase does not reside in its isomerase activity

1993 • 201 citations

Expression and site-directed mutagenesis of human protein disulfide isomerase in Escherichia coli. This multifunctional polypeptide has two independently acting catalytic sites for the isomerase activity.

1992 • 144 citations

Unfolded proteins stimulate molecular chaperone Hsc70 ATPase by accelerating ADP/ATP exchange

1992 • 132 citations

Translocation of ATP into the lumen of rough endoplasmic reticulum-derived vesicles and its binding to luminal proteins including BiP (GRP 78) and GRP 94.

1992 • 131 citations

Effects of the chaperonin GroE on the refolding of tryptophanase from Escherichia coli. Refolding is enhanced in the presence of ADP.

1992 • 115 citations

Heat shock in Escherichia coli alters the protein-binding properties of the chaperonin groEL by inducing its phosphorylation

1992 • 105 citations

Kinetics and specificity of homogeneous protein disulphide-isomerase in protein disulphide isomerization and in thiol-protein-disulphide oxidoreduction

1983 • 102 citations

Effect of protein and peptide inhibitors on the activity of protein disulfide-isomerase

1991 • 87 citations

Enzymatic Catalysis of Disulfide Formation

1994 • 77 citations

Folding in vitro of bovine pancreatic trypsin inhibitor in the presence of proteins of the endoplasmic reticulum

1992 • 65 citations

An ATP transporter is required for protein translocation into the yeast endoplasmic reticulum.

1993 • 65 citations

Role of accessory proteins in protein folding

1993 • 56 citations

A major phosphoprotein of the endoplasmic reticulum is protein disulfide isomerase.

1994 • 56 citations

Fluorescence detection of conformational changes in GroEL induced by thermal switching and nucleotide binding.

1994 • 26 citations

Association and dissociation of protein disulfide isomerase

1994 • 23 citations

A pleîotropic acid phosphatase-deficient mutant of Escherichia coli shows premature termination in the dsbA gene. Use of dsbA :: phoA furions to localize a structurally important domain in DsbA

1994 • 13 citations