Recognition of Alzheimer paired helical filaments by monoclonal neurofilament antibodies is due to crossreaction with tau protein.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

1986 • 3,430 citations

Microtubule Assembly in the Absence of Added Nucleotides

1973 • 2,055 citations

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

1986 • 1,709 citations

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.

1986 • 1,387 citations

Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ.

1983 • 1,162 citations

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

1963 • 956 citations

Phosphorylation affects the ability of tau protein to promote microtubule assembly.

1984 • 852 citations

Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)

1986 • 729 citations

Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants

1982 • 541 citations

Phosphorylated Tau Protein Is Integrated into Paired Helical Filaments in Alzheimer's Disease1

1986 • 504 citations

Aberrant neurofilament phosphorylation in Alzheimer disease.

1985 • 339 citations

One of the Antigenic Determinants of Paired Helical Filaments Is Related to Tau Protein1

1986 • 336 citations

Phosphorylation of microtubule-associated proteins regulates their interaction with actin filaments.

1983 • 319 citations

Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteins

1983 • 252 citations

Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles.

1984 • 227 citations

Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.

1985 • 220 citations

Recognition of tau epitopes by anti-neurofilament antibodies that bind to Alzheimer neurofibrillary tangles.

1987 • 181 citations

Phosphorylated Neurofilament Antigens in Neurofibrillary Tangles in Alzheimerʼs Disease

1986 • 158 citations

Alzheimer's paired helical filaments share epitopes with neurofilament side arms.

1986 • 132 citations

EVIDENCE THAT ALZHEIMER NEUROFIBRILLARY TANGLES ORIGINATE FROM NEUROTUBULES

1979 • 125 citations

Novel monoclonal antibodies provide evidence for the in situ existence of a nonphosphorylated form of the largest neurofilament subunit

1986 • 114 citations

Immunostaining of neurofibrillary tangles in Alzheimer's senile dementia with a neurofilament antiserum

1982 • 97 citations

Immunocytochemical studies of neurofibrillary tangles.

1981 • 78 citations

Alzheimer's disease: Immunoreactivity of neurofibrillary tangles with anti-neurofilament and anti-paired helical filament antibodies

1984 • 76 citations

A monoclonal antibody that cross-reacts with phosphorylated epitopes on two microtubule-associated proteins and two neurofilament polypeptides.

1986 • 66 citations

Alzheimer's disease: exposure of neurofilament immunoreactivity in SDS-insoluble paired helical filaments

1984 • 30 citations

Proteolytic Fragments of Alzheimer's Paired Helical Filaments1

1985 • 26 citations