The DNA binding domain of the Varicella-zoster virus gene 62 protein interacts with multiple sequences which are similar to the binding site of the related protein of herpes simplex virus type 1

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

The Complete DNA Sequence of the Long Unique Region in the Genome of Herpes Simplex Virus Type 1

1988 • 1,618 citations

Regulation of Herpesvirus Macromolecular Synthesis I. Cascade Regulation of the Synthesis of Three Groups of Viral Proteins

1974 • 1,479 citations

The Complete DNA Sequence of Varicella-Zoster Virus

1986 • 1,425 citations

Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4

1985 • 702 citations

Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK

1979 • 496 citations

Trans activation of transcription by herpes virus products: requirement for two HSV-1 immediate-early polypeptides for maximum activity.

1984 • 396 citations

Complete DNA sequence of the short repeat region in the genome of herpes simplex virus type 1

1986 • 335 citations

Temporal regulation of herpes simplex virus type 1 transcription: location of transcripts on the viral genome

1977 • 274 citations

Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4

1988 • 225 citations

Binding of the herpes simplex virus immediate-early gene product ICP4 to its own transcription start site

1987 • 158 citations

Direct correlation between a negative autoregulatory response element at the cap site of the herpes simplex virus type 1 IE175 (alpha 4) promoter and a specific binding site for the IE175 (ICP4) protein

1988 • 149 citations

Transcription and DNA sequence of the BamHI L fragment of B95-8 Epstein-Barr virus.

1984 • 128 citations

DNA bending by negative regulatory proteins: Gal and Lac repressors.

1989 • 106 citations

The regulation of transcription of viral and cellular genes by herpesvirus immediate-early gene products (review).

1987 • 102 citations

Mutational dissection of the HSV-1 immediate-early protein Vmw175 involved in transcriptional transactivation and repression

1988 • 88 citations

The regions of the herpes simplex virus type 1 immediate early protein Vmwl75 required for site specific DNA binding closely correspond to those involved in transcriptional regulation

1988 • 87 citations

Cell lines containing varicella-zoster virus open reading frame 62 and expressing the "IE" 175 protein complement ICP4 mutants of herpes simplex virus type 1

1988 • 83 citations

Transactivation of plasmid-borne promoters by adenovirus and several herpes group viruses

1984 • 81 citations

The conserved DNA-binding domains encoded by the herpes simplex virus type 1 ICP4, pseudorabies virus IE180, and varicella-zoster virus ORF62 genes recognize similar sites in the corresponding promoters

1991 • 74 citations

The immediate early proteins of varicella-zoster virus

1987 • 57 citations

Control of expression of the varicella-zoster virus major immediate early gene

1990 • 54 citations

A herpes simplex virus type 1 recombinant with both copies of the Vmw175 coding sequences replaced by the homologous varicella-zoster virus open reading frame

1990 • 51 citations

A predictive model for DNA recognition by the herpes simplex virus protein ICP4

1991 • 51 citations

The Product of Varicella-zoster Virus Gene 62 Autoregulates Its Own Promoter

1990 • 49 citations

Differential regulation by varicella-zoster virus (VZV) and herpes simplex virus type-1 trans-activating genes

1989 • 44 citations

Varicella-zoster virus complements herpes simplex virus type 1 temperature-sensitive mutants

1987 • 40 citations

Codons 262 to 490 from the herpes simplex virus ICP4 gene are sufficient to encode a sequence-specific DNA binding protein

1990 • 39 citations

Transcriptionally active immediate-early protein of pseudorabies virus binds to specific sites on class II gene promoters

1989 • 32 citations

DNA binding and gene regulation by the herpes simplex virus type 1 protein ICP4 and involvement of the TATA element

1989 • 31 citations

Purification of the DNA binding domain of herpes simplex virus type 1 immediate-early protein Vmw175 as a homodimer and extensive mutagenesis of its DNA recognition site

1991 • 18 citations

The major transcriptional regulatory protein of herpes simplex virus type 1 includes a protease resistant DNA binding domain

1990 • 14 citations

Nucleotides within both proximal and distal parts of the consensus sequence are important for specific DNA recognition by the herpes simplex virus regulatory protein ICP4

1991 • 13 citations

Herpes simplex virus type 1 polypeptide ICP4 bends DNA

1992 • 10 citations

Immediate early protein of pseudorabies virus is a general transactivator but stimulates only suboptimally utilized promoters

1990 • 8 citations