Assessing the impact of Plasmodium falciparum genome sequencing

Human Malaria Parasites in Continuous Culture

1976 • 7,687 citations

A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae

2000 • 4,734 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

Life with 6000 Genes

1996 • 4,125 citations

Serial Analysis of Gene Expression

1995 • 3,659 citations

Use of a cDNA microarray to analyse gene expression patterns in human cancer

1996 • 2,002 citations

Linking genome and proteome by mass spectrometry: Large-scale identification of yeast proteins from two dimensional gels

1996 • 1,430 citations

The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytes

1995 • 1,223 citations

Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis as Antimalarial Drugs

1999 • 1,175 citations

Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes

1995 • 1,035 citations

Switches in expression of plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes

1995 • 1,003 citations

Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration.

1985 • 839 citations

Nuclear-encoded proteins target to the plastid inToxoplasma gondiiandPlasmodium falciparum

1998 • 705 citations

Intercellular adhesion molecule-1 is an endothelial cell adhesion receptor for Plasmodium falciparum

1989 • 703 citations

Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum

1998 • 615 citations

P. falciparum rosetting mediated by a parasite-variant erythrocyte membrane protein and complement-receptor 1

1997 • 584 citations

Developmental selection of var gene expression in Plasmodium falciparum

1998 • 532 citations

Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiae.

1994 • 495 citations

Chromosome 2 Sequence of the Human Malaria Parasite Plasmodium falciparum

1998 • 455 citations

Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodies

1990 • 453 citations

Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes.

1984 • 451 citations

Transfection of Plasmodium falciparum within human red blood cells.

1995 • 383 citations

A human 88-kD membrane glycoprotein (CD36) functions in vitro as a receptor for a cytoadherence ligand on Plasmodium falciparum-infected erythrocytes.

1989 • 377 citations

Rifins: A second family of clonally variant proteins expressed on the surface of red cells infected with Plasmodium falciparum

1999 • 334 citations

The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum

1999 • 322 citations

stevor and rif are Plasmodium falciparum multicopy gene families which potentially encode variant antigens

1998 • 273 citations

The adhesion ofPlasmodium falciparum-infected erythrocytes to chondroitin sulfate A is mediated byP. falciparumerythrocyte membrane protein 1

1999 • 263 citations

Genetic Polymorphism and Natural Selection in the Malaria Parasite Plasmodium falciparum

1998 • 244 citations

Leishmania majorFriedlin chromosome 1 has an unusual distribution of protein-coding genes

1999 • 234 citations

Shotgun DNA microarrays and stage‐specific gene expression in Plasmodium falciparum malaria

2000 • 214 citations

Small, Clonally Variant Antigens Expressed on the Surface of the Plasmodium falciparum–Infected Erythrocyte Are Encoded by the rif Gene Family and Are the Target of Human Immune Responses

1999 • 214 citations

Knob-positive and knob-negative Plasmodium falciparum differ in expression of a strain-specific malarial antigen on the surface of infected erythrocytes.

1984 • 178 citations

A global strategy for malaria control

1994 • 177 citations

MicroSAGE: a modified procedure for serial analysis of gene expression in limited amounts of tissue

1999 • 175 citations

Cytoadherence by Plasmodium falciparum-infected erythrocytes is correlated with the expression of a family of variable proteins on infected erythrocytes.

1988 • 171 citations

Toward a High-ResolutionPlasmodium falciparumLinkage Map: Polymorphic Markers from Hundreds of Simple Sequence Repeats

1996 • 165 citations

Transfection of Plasmodiium falciparum within human red biood cells

1995 • 163 citations

Trans-kingdom Transposition of the Drosophila Element mariner Within the Protozoan Leishmania

1997 • 146 citations

Transfection of the human malaria parasite Plasmodium falciparum

1999 • 136 citations

The var genes of Plasmodium falciparum are located in the subtelomeric region of most chromosomes.

1996 • 135 citations

Transfection of Malaria Parasites

1997 • 133 citations

The genome of Plasmodium falciparum. I: DNA base composition

1982 • 124 citations

Centromeres: proteins, protein complexes, and repeated domains at centromeres of simple eukaryotes

1998 • 122 citations

Continuous culture of Plasmodium falciparum: its impact on malaria research

1997 • 119 citations

An RFLP map of the Plasmodium falciparum genome, recombination rates and favored linkage groups in a genetic cross

1992 • 113 citations

Antigenic Variation in Malaria

1999 • 112 citations

Control of gene expression in Plasmodium falciparum

1998 • 102 citations

A shotgun optical map of the entire Plasmodium falciparum genome

1999 • 82 citations

Parasitism and chromosome dynamics in protozoan parasites: is there a connection?

1995 • 77 citations

Genomic organisation and chromatin structure of Plasmodium falciparum chromosome ends

2000 • 77 citations

An enlarged largest subunit orPlasmodium falciparumRNA polymerase II defines conserved and variable RNA polymerase domains

1989 • 75 citations

The polymorphic subtelomeric regions of Plasmodium falciparum chromosomes contain arrays of repetitive sequence elements.

1994 • 73 citations

The chromosomal organization of the Plasmodium falciparum var gene family is conserved

1997 • 69 citations

European functional analysis network (EUROFAN) and the functional analysis of the Saccharomyces cerevisiae genome (minireview)

1998 • 64 citations

Transcriptional differences in polymorphic and conserved domains of a complete cloned P. falciparum chromosome

1993 • 61 citations

The cytoadherence linked asexual gene family of Plasmodium falciparum : are there roles other than cytoadherence? 1Note: Nucleotide sequence data reported in this paper are available in the GenBank data base under the accession numbers AF055476, AE001362 and Z97348 and at the databases of the Sanger Centre (http://www.sanger.ac.uk/Projects/P_falciparum) and the Institute for Genomic Reaseach (http://www.tigr.org/tdb/mdb/pfdb). 1

1999 • 55 citations

Current status of the Plasmodium falciparum genome project

1996 • 52 citations

Proteome mapping, mass spectrometric sequencing and reverse transcription‐PCR for characterization of the sulfate starvation‐induced response in Pseudomonas aeruginosa PAO1

1999 • 48 citations

A Study of Polymorphism in the Circumsporozoite Protein of Human Malaria Parasites

1994 • 44 citations

From gene to screen with yeast

1997 • 39 citations

Intraerythrocytic polyubiquitin expression in Plasmodium falciparum is subjected to developmental and heat-hock control☆

2000 • 39 citations

The gene encoding topoisomerase I from the human malaria parasite Plasmodium falciparum

1995 • 28 citations

Identification of Plasmodium falciparum-infected mosquitoes using a probe containing repetitive DNA

1989 • 27 citations

Finding genes in Plasmodium falciparum

2000 • 24 citations

Construction and Characterization of aPlasmodium vivaxGenomic Library in Yeast Artificial Chromosomes

1997 • 22 citations

Finding genes in Plasmodium falciparum

2000 • 14 citations

A YAC contig and high resolution restriction map of chromosome 3 from Plasmodium falciparum

1997 • 7 citations

Malaria Genome Project Task Force: A Post-genomic Agenda for Functional Analysis

1999 • 6 citations