Underlying disorders associated with severe early-onset preeclampsia

Mutation in blood coagulation factor V associated with resistance to activated protein C

1994 • 3,871 citations

Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease

1991 • 2,191 citations

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.

1993 • 1,997 citations

Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study

1993 • 1,283 citations

The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

1985 • 1,251 citations

Heterozygosity for Homocystinuria in Premature Peripheral and Cerebral Occlusive Arterial Disease

1985 • 739 citations

Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum

1991 • 702 citations

Absence of Thrombosis in Subjects with Heterozygous Protein C Deficiency

1987 • 529 citations

Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease.

1989 • 510 citations

The Second International Anti-Cardiolipin Standardization Workshop/The Kingston Anti-Phospholipid Antibody Study (KAPS) Group

1990 • 420 citations

Maternal hyperhomocysteinemia: A risk factor for neural-tube defects?

1994 • 402 citations

Protein C deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study) [see comments]

1995 • 372 citations

Prevalence of antithrombin deficiency in the healthy population

1994 • 363 citations

Hyperhomocysteinemia: a risk factor in women with unexplained recurrent early pregnancy loss

1993 • 294 citations

Enhanced thrombin generation in normal and hypertensive pregnancy

1989 • 231 citations

Coagulation screen is more specific than the anticardiolipin antibody ELISA in defining a thrombotic subset of lupus patients.

1988 • 141 citations

Combined vitamin B6 plus folic acid therapy in young patients with arteriosclerosis and hyperhomocysteinemia

1994 • 121 citations

Interlaboratory variation in antiphospholipid antibody testing

1992 • 108 citations

Protein C: Comparison of different assays in normal and abnormal plasma samples

1987 • 55 citations

The simultaneous measurement of total and free protein S by ELISA

1988 • 48 citations

Laboratory Diagnosis of Antithrombin and Heparin Cofactor II Deficiency

1990 • 47 citations

Tumor necrosis factor-alpha downregulates protein S secretion in human microvascular and umbilical vein endothelial cells but not in the HepG- 2 hepatoma cell line

1994 • 47 citations

Association of a novel high oxygen affinity haemoglobin variant with δβ thalassaemia

1994 • 24 citations