Evidence for the Hebbian hypothesis in experience-dependent physiological plasticity of neocortex: a critical review

Parallel Distributed Processing: Explorations in the Microstructure of Cognition: Foundations

1986 • 15,232 citations

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

The organization of behavior

1988 • 8,668 citations

The Cognitive neurosciences

2005 • 4,777 citations

Thalamocortical Oscillations in the Sleeping and Aroused Brain

1993 • 3,483 citations

A theory of cerebellar cortex

1969 • 3,204 citations

Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex

1982 • 2,824 citations

SINGLE-CELL RESPONSES IN STRIATE CORTEX OF KITTENS DEPRIVED OF VISION IN ONE EYE

1963 • 2,565 citations

COMPARISON OF THE EFFECTS OF UNILATERAL AND BILATERAL EYE CLOSURE ON CORTICAL UNIT RESPONSES IN KITTENS

1965 • 1,604 citations

BINOCULAR INTERACTION IN STRIATE CORTEX OF KITTENS REARED WITH ARTIFICIAL SQUINT

1965 • 1,377 citations

Plasticity in the frequency representation of primary auditory cortex following discrimination training in adult owl monkeys

1993 • 1,280 citations

Brainstem Control of Wakefulness and Sleep

1990 • 1,188 citations

A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory.

1989 • 1,114 citations

Intracellular injections of EGTA block induction of hippocampal long-term potentiation

1983 • 1,106 citations

Organization of Behavior.

1950 • 1,082 citations

Nucleus basalis and thalamic control of neocortical activity in the freely moving rat

1988 • 1,035 citations

Cortical functional architecture and local coupling between neuronal activity and the microcirculation revealed by in vivo high-resolution optical imaging of intrinsic signals.

1990 • 967 citations

Plasticity of Sensory and Motor Maps in Adult Mammals

1991 • 916 citations

Different voltage-dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex

1990 • 893 citations

Anatomical organization of excitatory amino acid receptors and their pathways

1987 • 877 citations

Excitatory amino acid receptors and synaptic plasticity

1990 • 872 citations

Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1994 • 860 citations

Modulation of visual cortical plasticity by acetylcholine and noradrenaline

1986 • 851 citations

Long-term depression of excitatory synaptic transmission and its relationship to long-term potentiation

1993 • 780 citations

Temporal contiguity requirements for long-term associative potentiation/depression in the hippocampus

1983 • 773 citations

Patterned Activity, Synaptic Convergence, and the NMDA Receptor in Developing Visual Pathways

1990 • 765 citations

A Physiological Mechanism for Hebb's Postulate of Learning

1973 • 711 citations

A critical period for long-term potentiation at thalamocortical synapses

1995 • 702 citations

A Cellular Mechanism of Classical Conditioning in Aplysia : Activity-Dependent Amplification of Presynaptic Facilitation

1983 • 620 citations

The nucleus basalis magnocellularis: The origin of a cholinergic projection to the neocortex of the rat

1980 • 617 citations

Plasticity of frequency organization in auditory cortex of guinea pigs with partial unilateral deafness

1989 • 593 citations

Cellular bases of neocortical activation: modulation of neural oscillations by the nucleus basalis and endogenous acetylcholine

1992 • 590 citations

Effects of sleep and arousal on the processing of visual information in the cat

1981 • 589 citations

Hebbian synapses in hippocampus.

1986 • 560 citations

Hebbian Synapses: Biophysical Mechanisms and Algorithms

1990 • 551 citations

A Physiological Basis for a Theory of Synapse Modification

1987 • 535 citations

GABAergic Neurons and Their Role in Cortical Plasticity in Primates

1993 • 499 citations

Disruption of experience-dependent synaptic modifications in striate cortex by infusion of an NMDA receptor antagonist

1990 • 497 citations

Electrophysiological studies of NMDA receptors

1987 • 483 citations

Associative long-term depression in the hippocampus induced by hebbian covariance

1989 • 470 citations

Effects of putative neurotransmitters on neuronal activity in monkey auditory cortex

1975 • 451 citations

Co-regulation of long-term potentiation and experience-dependent synaptic plasticity in visual cortex by age and experience

1995 • 428 citations

Effects of locus coeruleus activation on electroencephalographic activity in neocortex and hippocampus

1991 • 417 citations

Hebbian synapses in visual cortex

1994 • 416 citations

Classical conditioning induces CS-specific receptive field plasticity in the auditory cortex of the guinea pig

1990 • 399 citations

The Influence of Prior Synaptic Activity on the Induction of Long-Term Potentiation

1992 • 398 citations

Suitability of urethane anesthesia for physiopharmacological investigations in various systems Part 1: General considerations

1986 • 389 citations

Dependence of Cortical Plasticity on Correlated Activity of Single Neurons and on Behavioral Context

1992 • 366 citations

Effect of unilateral partial cochlear lesions in adult cats on the representation of lesioned and unlesioned cochleas in primary auditory cortex

1993 • 356 citations

Reorganization of Cortical Representations of the Hand Following Alterations of Skin Inputs Induced by Nerve Injury, Skin Island Transfers, and Experience

1993 • 356 citations

Postsynaptic control of plasticity in developing somatosensory cortex

1993 • 341 citations

Binocular competition in the control of geniculate cell growth

1972 • 338 citations

Development of neuronal selectivity in primary visual cortex of cat.

1984 • 336 citations

Postsynaptic hyperpolarization during conditioning reversibly blocks induction of long-term potentiation

1986 • 324 citations

Long-Term Potentiation in the Motor Cortex

1989 • 320 citations

Interaction of norepinephrine with cerebrocortical activity evoked by stimulation of somatosensory afferent pathways in the rat☆

1980 • 320 citations

Dynamic Regulation of Receptive Fields and Maps in the Adult Sensory Cortex

1995 • 319 citations

The Role of NMDA Receptors in Information Processing

1993 • 313 citations

The location and function of NMDA receptors in cat and kitten visual cortex

1989 • 310 citations

NEURAL INPUTS INTO THE NUCLEUS BASALIS OF THE SUBSTANTIA INNOMINATA (Ch4) IN THE RHESUS MONKEY

1984 • 305 citations

Experience-dependent plasticity in adult rat barrel cortex.

1993 • 304 citations

Receptive fields in the body-surface map in adult cortex defined by temporally correlated inputs

1988 • 297 citations

Laminar Comparison of Somatosensory Cortical Plasticity

1994 • 293 citations

Hippocampal long‐term potentiation is induced by pairing single afferent volleys with intracellular^ injected depolarizing current pulses

1986 • 284 citations

Responses of neurons in auditory cortex of the macaque monkey to monaural and binaural stimulation

1973 • 276 citations

Mechanisms of visual plasticity: Hebb synapses, NMDA receptors, and beyond

1991 • 274 citations

Agonists of cholinergic and noradrenergic receptors facilitate synergistically the induction of long-term potentiation in slices of rat visual cortex

1992 • 274 citations

Neural plasticity without postsynaptic action potentials: less-active inputs become dominant when kitten visual cortical cells are pharmacologically inhibited.

1988 • 272 citations

A cellular analogue of visual cortical plasticity

1988 • 256 citations

The effects of early visual experience on the cat's visual cortex and their possible explanation by Hebb synapses.

1981 • 218 citations

Associative Induction of Posttetanic and Long-Term Potentiation in CA1 Neurons of Rat Hippocampus

1986 • 216 citations

Cortical plasticity and memory

1993 • 215 citations

Rapid development of learning-induced receptive field plasticity in the auditory cortex.

1993 • 213 citations

The sensitive period in the development of the trigeminal system of the neonatal rat

1980 • 212 citations

Stimulation of the nucleus basalis of Meynert increases acetylcholine release in the cerebral cortex in rats

1989 • 208 citations

Receptive field plasticity in the auditory cortex during frequency discrimination training: Selective retuning independent of task difficulty.

1993 • 203 citations

Long-term retention of learning-induced receptive-field plasticity in the auditory cortex.

1993 • 202 citations

Expansion of the Cortical Representation of a Specific Skin Field in Primary Somatosensory Cortex by Intracortical Microstimulation

1992 • 192 citations

Classical conditioning rapidly induces specific changes in frequency receptive fields of single neurons in secondary and ventral ectosylvian auditory cortical fields

1986 • 185 citations

The predictive brain: temporal coincidence and temporal order in synaptic learning mechanisms.

1994 • 184 citations

Long-term enhancement of evoked potentials in cat somatosensory cortex produced by co-activation of the basal forebrain and cutaneous receptors

1988 • 181 citations

Electrophysiological Contributions to the Neural Basis of Learning

1961 • 179 citations

Cholinergic depletion prevents expansion of topographic maps in somatosensory cortex.

1991 • 172 citations

Learning-induced changes of auditory receptive fields

1993 • 171 citations

Postsynaptic control of the induction of long-term changes in efficacy of transmission at neocortical synapses in slices of rat brain

1988 • 166 citations

The biology of change in otolaryngology

1988 • 165 citations

A test of Hebb's postulate at identified synapses which mediate classical conditioning in Aplysia

1984 • 164 citations

Control of Thalamocortical Afferent Rearrangement by Postsynaptic Activity in Developing Visual Cortex

1994 • 162 citations

Advances in neural and behavioral development

1985 • 155 citations

A reappraisal of the functions of the nucleus basalis of Meynert

1988 • 151 citations

Immediate and Delayed Changes of Rat Motor Cortical Output Representation with New Forelimb Configurations

1992 • 150 citations

Long-term potentiation of thalamic input to the motor cortex induced by coactivation of thalamocortical and corticocortical afferents

1991 • 150 citations

Acetylcholine produces stimulus-specific receptive field alterations in cat auditory cortex

1989 • 148 citations

New evidence for a gating action of norepinephrine in central neuronal circuits of mammalian brain

1988 • 147 citations

Habituation produces frequency-specific plasticity of receptive fields in the auditory cortex.

1991 • 146 citations

Neuroplasticity of the adult primate auditory cortex following cochlear hearing loss.

1993 • 145 citations

Basal forebrain stimulation modifies auditory cortex responsiveness by an action at muscarinic receptors

1991 • 144 citations

Long‐term changes in synaptic strength along specific intrinsic pathways in the cat visual cortex.

1993 • 134 citations

Effects of ionophoresed noradrenaline on the spontaneous activity of neurones in rat primary somatosensory cortex.

1983 • 133 citations

Long-lasting potentiation of synaptic transmission requires postnaptic modifications in the neocortex

1987 • 133 citations

Cellular Mechanisms of Conditioning and Behavioral Plasticity

1988 • 132 citations

Do NMDA receptors have a critical function in visual cortical plasticity?

1993 • 131 citations

Hebbian Depression of Isolated Neuromuscular Synapses in Vitro

1992 • 128 citations

Theta pattern stimulation and the induction of LTP: the sequence in which synapses are stimulated determines the degree to which they potentiate

1989 • 127 citations

Properties of associative long-lasting potentiation induced by cellular conditioning in the motor cortex of conscious cats

1991 • 123 citations

Age-dependent long-term potentiation of inhibitory synaptic transmission in rat visual cortex

1994 • 122 citations

Hebbian induction of long-term potentiation of Aplysia sensorimotor synapses: partial requirement for activation of an NMDA-related receptor

1994 • 120 citations

Reorganization of auditory cortex after neonatal high frequency cochlear hearing loss

1991 • 118 citations

Synaptic plasticity in visual cortex: comparison of theory with experiment

1991 • 117 citations

Role of context in the expression of learning-induced plasticity of single neurons in auditory cortex.

1989 • 114 citations

Transient and prolonged facilitation of tone-evoked responses induced by basal forebrain stimulations in the rat auditory cortex

1994 • 113 citations

Cellular analogs of visual cortical epigenesis. I. Plasticity of orientation selectivity

1992 • 110 citations

Cortical activity blockade prevents ocular dominance plasticity in the kitten visual cortex

1986 • 109 citations

Basal forebrain stimulation facilitates tone-evoked responses in the auditory cortex of awake rat

1993 • 107 citations

Receptive-field plasticity in the adult auditory cortex induced by Hebbian covariance

1996 • 106 citations

Influence of mercurial sulfhydryl agents on aqueous outflow pathways in enucleated eyes.

1984 • 100 citations

Cholinergic modulation of frequency receptive fields in auditory cortex: II. Frequency‐specific effects of anticholinesterases provide evidence for a modulatory action of endogenous Ach

1989 • 94 citations

Basal Forebrain Lesions with or without Reserpine Injection Inhibit Cortical Reorganization in Rat Hindpaw Primary Somatosensory Cortex following Sciatic Nerve Section

1991 • 92 citations

Nucleus basalis involvement in conditioned neuronal responses in the rat frontal cortex

1986 • 92 citations

Neural substrates for tone-conditioned bradycardia demonstrated with 2-deoxyglucose. II. Auditory cortex plasticity

1986 • 92 citations

NMDA‐dependent heterosynaptic long‐term depression in the dentate gyrus of anaesthetized rats

1992 • 89 citations

Temporal covariance of pre- and postsynaptic activity regulates functional connectivity in the visual cortex

1994 • 85 citations

Acetylcholine modifies neuronal acoustic rate‐level functions in guinea pig auditory cortex by an muscarinic receptors

1990 • 83 citations

Visualization of Quantal Synaptic Transmission by Dendritic Calcium Imaging

1994 • 81 citations

The Hebb Rule for Synaptic Plasticity: Algorithms and Implementations

1989 • 81 citations

High Nervous Functions: Brain Functions and Learning

1961 • 78 citations

Horizontal long-term potentiation of responses in rat somatosensory cortex

1991 • 77 citations

Disruption of cortical activity prevents ocular dominance changes in monocularly deprived kittens

1984 • 74 citations

Functional reorganization of adult cat somatosensory cortex is dependent on NMDA receptors

1991 • 74 citations

Plasticity in cat visual cortex restored by electrical stimulation of the locus coeruleus

1985 • 70 citations

Cellular analogs of visual cortical epigenesis. II. Plasticity of binocular integration

1992 • 64 citations

Hebb synaptic plasticity

1984 • 64 citations

Evidence for a cholinergic mechanism of “learned” changes in the responses of barrel field neurons of the awake and undrugged rat

1990 • 62 citations

Identification of neurons producing long‐term potentiation in the cat motor cortex: Intracellular recordings and labeling

1990 • 62 citations

Alterations in correlated activity parallel ICMS-induced representational plasticity

1993 • 60 citations

Non-Hebbian synapses in rat visual cortex

1990 • 60 citations

Non-Hebbian properties of long-term potentiation enable high-capacity encoding of temporal sequences.

1994 • 60 citations

Sensitization induced receptive field plasticity in the auditory cortex is independent of CS-modality

1992 • 56 citations

Plasticity in auditory cortical circuitry

1994 • 56 citations

“Learned” changes in the responses of the rat barrel field neurons

1987 • 49 citations

Effects of NMDA antagonists on developmental plasticity in kitten visual cortex

1990 • 48 citations

Partial blocking of NMDA receptors restricts plastic changes in adult mouse barrel cortex

1995 • 47 citations

Conditioned changes in the basal forebrain: Relations with learning-induced cortical plasticity

1995 • 46 citations

Rapid dynamic changes in adult cerebral cortex

1993 • 43 citations

Minimal stimulus parameters and the effects of hyperpolarization on the induction of long-term potentiation in the cat motor cortex

1991 • 38 citations

Frequency-specific cellular changes in the auditory system during acquisition and reversal of discriminative conditioning

1990 • 37 citations

Induction of high frequency activity in the somatosensory thalamus of rats in vivo results in long-term potentiation of responses in SI cortex

1992 • 34 citations

Failure to Induce Long-term Depression by an Anti-Correlation Procedure in Area CA1 of the Rat Hippocampal Slice

1993 • 32 citations

Long-term facilitation of excitatory synaptic transmission in single motor cortical neurones of the cat produced by repetitive pairing of synaptic potentials and action potentials following intracellular stimulation

1981 • 31 citations

Dependence of LTP induction on postsynaptic depolarization: a perforated patch-clamp study in visual cortical slices of young rats

1994 • 30 citations

Chapter 13 Functional organization and learning-related plasticity in auditory cortex of the Mongolian gerbil

1993 • 29 citations

Investigation of β-adrenergic modulation of synaptic transmission and postsynaptic induction of associative LTP in layer V neurones in slices of rat sensorimotor cortex

1992 • 29 citations

Conditioning of cortical neurons in cats with antidromic activation as the unconditioned stimulus.

1977 • 27 citations

Sensory system neural activity during habituation of the pupillary orienting reflex

1975 • 25 citations

Functional and neuronal binocularity in kittens raised with rapidly alternating monocular occlusion

1987 • 25 citations

Chapter 45: The cholinergic neuromodulatory system: an evaluation of its functional roles

1993 • 24 citations

Neural systems contributing to acetylcholinesterase histochemical staining in primary visual cortex of the adult rat

1990 • 23 citations

The ?2-adrenergic antagonist idazoxan enhances the frequency selectivity and increases the threshold of auditory cortex neurons

1995 • 22 citations

What Does in Vivo Optical Imaging Tell Us about the Primary Visual Cortex in Primates?

1994 • 21 citations

Refining the temporal definition of an association at the neuronal level using long-term potentiation and long-term depression in the dentate gyrus

1991 • 13 citations

Role of the visual environment in the formation of receptive fields according to the BCM theory

1994 • 7 citations

Strabismus does not prevent recovery from monocular deprivation: A challenge for simple Hebbian models of synaptic modification

1989 • 7 citations

Long-Term Potentiation of Synaptic Transmission in the Hippocampus Obeys Hebb’s Rule for Synaptic Modification

1988 • 7 citations

Role of neural activity in development and plasticity of mammalian visual cortex

1989 • 4 citations

Specification of Cortical Neurons By Visuomotor Experience

1983 • 3 citations