The metabolism of xenobiotics and endogenous compounds by the constitutive dog liver cytochrome P450 PBD-2

Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

1982 • 1,021 citations

The P450 Gene Superfamily: Recommended Nomenclature

1987 • 812 citations

Microsomes, drug oxidations, and drug toxicity

1982 • 187 citations

Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver.

1985 • 150 citations

Cytochrome P-450 isozyme 1 from phenobarbital-induced rat liver: purification, characterization, and interactions with metyrapone and cytochrome b5

1983 • 132 citations

Metabolism of dichlorobiphenyls by highly purified isozymes of rat liver cytochrome P-450

1981 • 113 citations

Regioselective progesterone hydroxylation catalyzed by eleven rat hepatic cytochrome P-450 isozymes

1987 • 98 citations

Hydroxylation of prostaglandins by inducible isozymes of rabbit liver microsomal cytochrome P-450. Participation of cytochrome b5.

1982 • 86 citations

Purification and characterization of the dog hepatic cytochrome P-450 isozyme responsible for the metabolism of 2,2′,4,4′,5,5′-hexachlorobiphenyl

1987 • 83 citations

Metabolism of 2,2′,3,3′,6,6′-hexachlorobiphenyl and 2,2′,4,4′,5,5′-hexachlorobiphenyl by human hepatic microsomes

1983 • 71 citations

Effects of conditions for reconstitution with cytochrome b5 on the formation of products in cytochrome P-450-catalyzed reactions.

1986 • 70 citations

2,3,6,2',3',6'-hexachlorobiphenyl: distribution, metabolism, and excretion in the dog and the monkey.

1982 • 61 citations

Evidence for functional and structural multiplicity of pregnenolone-16.alpha.-carbonitrile-inducible cytochrome P-450 isozymes in rat liver microsomes

1987 • 54 citations

Xylene induces a cytochrome P-450 isozyme in rat liver similar to the major isozyme induced by phenobarbital.

1983 • 32 citations

Constitutive forms of rabbit-liver microsomal cytochrome P-450: Enzymatic diversity, polymorphism and allosteric regulation

1984 • 28 citations

2 3 6 2' 3' 6' hexa chloro bi phenyl distribution metabolism and excretion in the dog and the monkey macaca fascicularis

1982 • 26 citations

4,4?-Dichlorobiphenyl: Distribution, metabolism, and excretion in the dog and the monkey*1, *2

1980 • 25 citations

Microheterogeneity in the major phenobarbital-inducible forms of rabbit liver microsomal cytochrome P-450 as revealed by nucleotide sequencing of cloned cDNAs

1988 • 25 citations

Selective inactivation by chloramphenicol of the major phenobarbital-inducible isozyme of dog liver cytochrome P-450.

1987 • 24 citations

Regio‐Selectivity of Purified Forms of Rabbit Liver Microsomal Cytochrome P‐450 in the Metabolism of Benzo(a)pyrene, n‐Hexane and 7‐Ethoxyresorufin

1981 • 9 citations

THE IN VITRO METABOLISM OF POLYCHLORINATED BIPHENYLS: SPECIES VARIATION.

1984 • 2 citations