The Function of a Leader Peptide in Translocating Charged Amino Acyl Residues Across a Membrane

The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis

1981 • 868 citations

Multiple Mechanisms of Protein Insertion into and Across Membranes

1985 • 720 citations

Topogenic signals in integral membrane proteins

1988 • 715 citations

Predicting the orientation of eukaryotic membrane-spanning proteins.

1989 • 596 citations

Control of topology and mode of assembly of a polytopic membrane protein by positively charged residues

1989 • 587 citations

Effects of two sec genes on protein assembly into the plasma membrane of Escherichia coli.

1985 • 217 citations

Insertion of a multispanning membrane protein occurs sequentially and requires only one signal sequence

1988 • 185 citations

Alteration of the amino terminus of the mature sequence of a periplasmic protein can severely affect protein export in Escherichia coli.

1988 • 163 citations

Procoat, the precursor of M13 coat protein, requires an electrochemical potential for membrane insertion.

1980 • 149 citations

Positively charged residues are important determinants of membrane protein topology

1990 • 132 citations

High-level expression of M13 gene II protein from an inducible polycistronic messenger RNA

1985 • 130 citations

Alterations in the extracellular domain of M13 procoat protein make its membrane insertion dependent on secA and secY

1988 • 128 citations

DNA Packing in Filamentous Bacteriophages

1988 • 126 citations

Introduction of basic amino acid residues after the signal peptide inhibits protein translocation across the cytoplasmic membrane of Escherichia coli. Relation to the orientation of membrane proteins.

1988 • 100 citations

The biosynthesis of membrane-bound M13 coat protein. Energetics and assembly intermediates.

1982 • 97 citations

Initial steps in protein membrane insertion. Bacteriophage M13 procoat protein binds to the membrane surface by electrostatic interaction.

1990 • 95 citations

The cytoplasmic carboxy terminus of M13 procoat is required for the membrane insertion of its central domain

1986 • 92 citations

Nucleotide sequence of the genome of Pf3, an IncP-1 plasmid-specific filamentous bacteriophage of Pseudomonas aeruginosa

1985 • 72 citations

Bacteriophage M13 Procoat Protein Inserts Into the Plasma Membrane as a Loop Structure

1987 • 66 citations

Both hydrophobic domains of M13 procoat are required to initiate membrane insertion.

1986 • 65 citations

Efficient translocation of positively charged residues of M13 procoat protein across the membrane excludes electrophoresis as the primary force for membrane insertion.

1990 • 63 citations

Recombinant forms of M13 procoat with an OmpA leader sequence or a large carboxy-terminal extension retain their independence of secY function.

1987 • 53 citations

Major coat protein and single-stranded DNA-binding protein of filamentous virus Pf3.

1984 • 31 citations

The major coat protein gene of the filamentousPseudomonas aeruginosaphage Pf3: absence of an N-terminal leader signal sequence

1983 • 18 citations