Nucleotide change of codon 38 in the X gene of hepatitis B virus genotype C is associated with an increased risk of hepatocellular carcinoma

Risk of Hepatocellular Carcinoma Across a Biological Gradient of Serum Hepatitis B Virus DNA Level

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pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

1991 • 1,155 citations

Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B

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Hepatitis B Virus Genotype and DNA Level and Hepatocellular Carcinoma: A Prospective Study in Men

2005 • 568 citations

Mutations in the Precore Region of Hepatitis B Virus DNA in Patients with Fulminant and Severe Hepatitis

1991 • 536 citations

Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers

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Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma

2004 • 492 citations

A Hepatitis B Virus Mutant Associated with an Epidemic of Fulminant Hepatitis

1991 • 468 citations

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Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan

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Subtypes, Genotypes and Molecular Epidemiology of the Hepatitis B Virus as Reflected by Sequence Variability of the S-Gene

1995 • 409 citations

The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks

1993 • 372 citations

Genetic relatedness of hepatitis B viral strains of diverse geographical origin and natural variations in the primary structure of the surface antigen

1993 • 345 citations

Naturally Occurring Variants of Hepatitis B Virus

1999 • 261 citations

High prevalence of 1762T 1764A mutations in the basic core promoter of hepatitis B virus isolated from black africans with hepatocellular carcinoma compared with asymptomatic carriers

1999 • 258 citations

Hepatitis B virus genotype assignment using restriction fragment length polymorphism patterns

1999 • 247 citations

Genotypes and Clinical Phenotypes of Hepatitis B Virus in Patients with Chronic Hepatitis B Virus Infection

2002 • 213 citations

A novel variant genotype C of hepatitis B virus identified in isolates from Australian Aborigines: complete genome sequence and phylogenetic relatedness

2001 • 205 citations

Activation of intracellular signaling by hepatitis B and C viruses: C-viral core is the most potent signal inducer

2000 • 196 citations

Hepatocellular carcinoma

1992 • 180 citations

Hepatitis B Virus Genotype Distribution among Chronic Hepatitis B Virus Carriers in Shanghai, China

2001 • 177 citations

Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection.

1992 • 172 citations

Detection of hepatitis C virus ribonucleic acid in the serum by amplification with polymerase chain reaction.

1990 • 157 citations

Viral genotype and hepatitis B virus DNA levels are correlated with histological liver damage in HBeAg-negative chronic hepatitis B virus infection

2002 • 141 citations

Human hepatitis virus X gene encodes a regulatory domain that represses transactivation of X protein.

1994 • 122 citations

Genotype may correlate with liver carcinogenesis and tumor characteristics in cirrhotic patients infected with hepatitis B virus subtype adw

2001 • 114 citations

The hepatitis B virus X protein enhances AP-1 activation through interaction with Jab1

2005 • 100 citations

Comparison of serum hepatitis B surface antigen (HBsAg) and serum anticore with tissue HBsAg and hepatitis B core antigen (HBcAg)

1978 • 87 citations

Hepatitis B virus X protein transcription activation domains are neither required nor sufficient for cell transformation.

1998 • 78 citations

Clonal Analysis of Micronodules in Virus C-Induced Liver Cirrhosis Using Laser Capture Microdissection (LCM) and HUMARA Assay

2000 • 51 citations

X-gene Product Antagonizes the p53-mediated Inhibition of Hepatitis B Virus Replication through Regulation of the Pregenomic/Core Promoter

1995 • 38 citations

Recent research progress in hepatocellular carcinoma.

2002 • 19 citations

Characterization and Gene Cloning of Monoclonal Antibody Specific for the Hepatitis B Virus X Protein

2000 • 14 citations