Cdc42 Is a Substrate for Caspases and Influences Fas-induced Apoptosis

Caspases: Enemies Within

1998 • 6,923 citations

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

1996 • 2,665 citations

Suppression of TNF-α-Induced Apoptosis by NF-κB

1996 • 2,623 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Membrane and Morphological Changes in Apoptotic Cells Regulated by Caspase-Mediated Activation of PAK2

1997 • 742 citations

Ras signalling and apoptosis

1998 • 559 citations

Cdc42: An Essential Rho-Type GTPase Controlling Eukaryotic Cell Polarity

1999 • 546 citations

Caspase-dependent Cleavage of Signaling Proteins during Apoptosis

1998 • 420 citations

PAK to the future

1999 • 391 citations

Cell cycle-dependent activation of Ras

1996 • 389 citations

p21-Activated Kinase 1 Phosphorylates the Death Agonist Bad and Protects Cells from Apoptosis

2000 • 356 citations

A Novel Regulator of p21-activated Kinases

1998 • 313 citations

Epidermal Growth Factor Protects Epithelial Cells against Fas-induced Apoptosis

1999 • 257 citations

Rho Family Proteins Modulate Rapid Apoptosis Induced by Cytotoxic T Lymphocytes and Fas

2000 • 244 citations

The Akt Proto-oncogene Links Ras to Pak and Cell Survival Signals

2000 • 235 citations

A novel Cdc42Hs mutant induces cellular transformation

1997 • 213 citations

The γ-subunit of the coatomer complex binds Cdc42 to mediate transformation

2000 • 211 citations

Stimulation of NFκB Activity by Multiple Signaling Pathways Requires PAK1

2000 • 188 citations

Specific Contributions of the Small GTPases Rho, Rac, and Cdc42 to Dbl Transformation

1999 • 177 citations

Oncogenic Ras inhibits Fas ligand-mediated apoptosis by downregulating the expression of Fas

1999 • 159 citations

NF-κB functions as both a proapoptotic and antiapoptotic regulatory factor within a single cell type

1999 • 159 citations

Fas-induced Apoptosis Is Mediated by Activation of a Ras and Rac Protein-regulated Signaling Pathway

1996 • 96 citations

Investigation of the GTP-Binding/GTPase Cycle of Cdc42Hs Using Fluorescence Spectroscopy

1994 • 59 citations

Transformation Activity of Cdc42 Requires a Region Unique to Rho-related Proteins

1998 • 46 citations

Contribution of Gene-Specific Lesions, DNA-Replication-Associated Damage, and Subsequent Transcriptional Inhibition in Topoisomerase Inhibitor-Mediated Apoptosis in Lymphoma Cells

1998 • 35 citations

Ras-GTPase activating protein inhibition specifically induces apoptosis of tumour cells

1999 • 34 citations