Developments in pharmacotherapy for tobacco dependence: past, present and future

Treating tobacco use and dependence-Clinical practice guideline

2000 • 3,721 citations

Nicotine replacement therapy for smoking cessation

2012 • 2,516 citations

Smoking and Mental Illness

2000 • 2,480 citations

Smoking and Carcinoma of the Lung

1950 • 1,909 citations

Biochemical verification of tobacco use and cessation

2002 • 1,760 citations

A Controlled Trial of Sustained-Release Bupropion, a Nicotine Patch, or Both for Smoking Cessation

1999 • 1,635 citations

Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study

2005 • 1,509 citations

Antidepressants for smoking cessation

2020 • 1,245 citations

Interventions to Enhance Patient Adherence to Medication Prescriptions

2002 • 1,131 citations

Comparison of tests used to distinguish smokers from nonsmokers.

1987 • 1,005 citations

TOBACCO SMOKING AS A POSSIBLE ETIOLOGIC FACTOR IN BRONCHIOGENIC CARCINOMA

1950 • 990 citations

Subgroup analyses in randomized trials: risks of subgroup-specific analyses;

2004 • 637 citations

Bupropion is a nicotinic antagonist.

2000 • 490 citations

Effect of smokeless tobacco (snus) on smoking and public health in Sweden

2003 • 460 citations

Smoking cessation with and without assistance

2000 • 408 citations

Nortriptyline and Cognitive-Behavioral Therapy in the Treatment of Cigarette Smoking

1998 • 400 citations

SR141716, a central cannabinoid (CB1) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in rats

2002 • 397 citations

Addressing tobacco among individuals with a mental illness or an addiction

2004 • 358 citations

The English smoking treatment services: one‐year outcomes

2005 • 354 citations

Nicotine Transdermal Patch and Atypical Antipsychotic Medications for Smoking Cessation in Schizophrenia

2000 • 354 citations

What to Do With a Patient Who Smokes

2005 • 295 citations

Effect of nicotine on the tobacco withdrawal syndrome

1984 • 293 citations

Randomised controlled trial of nasal nicotine spray in smoking cessation

1992 • 285 citations

Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine.

1999 • 280 citations

Randomised controlled trial of nicotine chewing-gum.

1982 • 271 citations

High-Dose Nicotine Patch Therapy

1995 • 253 citations

Clonidine for smoking cessation

2004 • 247 citations

Impact of Over-the-Counter Sales on Effectiveness of Pharmaceutical Aids for Smoking Cessation

2002 • 244 citations

Interventions to Enhance Patient Adherence to Medication Prescriptions

2002 • 218 citations

A meta-analysis of the efficacy of over-the-counter nicotine replacement

2003 • 206 citations

A Double-blind Trial of a Nicotine Inhaler for Smoking Cessation

1993 • 201 citations

Clozapine decreases smoking in patients with chronic schizophrenia

1995 • 200 citations

CONTROLLED TRIAL OF TRANSDERMAL NICOTINE PATCH IN TOBACCO WITHDRAWAL

1989 • 199 citations

A randomized trial of concurrent versus delayed smoking intervention for patients in alcohol dependence treatment.

2004 • 181 citations

Effects of clozapine on smoking in chronic schizophrenic outpatients.

1995 • 180 citations

Smoking and therapeutic response to clozapine in patients with schizophrenia

1999 • 174 citations

Dose effects and predictors of outcome in a randomized trial of transdermal nicotine patches in general practice

2003 • 173 citations

Antidepressants for smoking cessation

2004 • 173 citations

A reversible monoamine oxidase A inhibitor (moclobemide) facilitates smoking cessation and abstinence in heavy, dependent smokers*

1995 • 167 citations

Smoking reduction promotes smoking cessation: results from a double blind, randomized, placebo‐controlled trial of nicotine gum with 2‐year follow‐up

2003 • 167 citations

Extended Nortriptyline and Psychological Treatment for Cigarette Smoking

2004 • 157 citations

Nicotine patch therapy in 101 adolescent smokers: efficacy, withdrawal symptom relief, and carbon monoxide and plasma cotinine levels.

2000 • 156 citations

Carboxyhemoglobin, cotinine, and thiocyanate assay compared for distinguishing smokers from non-smokers.

1984 • 143 citations

Aiding reduction of smoking with nicotine replacement medications: hope for the recalcitrant smoker?

1997 • 138 citations

Reducing tobacco harm: Research challenges and issues

2002 • 135 citations

Nicotine vs Placebo Gum in General Medical Practice

1989 • 128 citations

Opioid antagonists for smoking cessation

2013 • 127 citations

Comparison of four methods of smoking withdrawal in patients with smoking related diseases. Report by a subcommittee of the Research Committee of the British Thoracic Society.

1983 • 126 citations

Nicotine replacement: ten-week effects on tobacco withdrawal symptoms

1989 • 124 citations

CB receptor antagonists for the treatment of nicotine addiction

2005 • 124 citations

Where there's smoke, there's fire: high prevalence of smoking among some sub-populations and recommendations for intervention

2006 • 122 citations

Dose effects and predictors of outcome in a randomized trial of transdermal nicotine patches in general practice

1995 • 121 citations

Tobacco Smoking and Nicotine

1987 • 115 citations

Individualizing Nicotine Replacement Therapy for the Treatment of Tobacco Dependence

2004 • 111 citations

Smoking reduction, smoking cessation, and incidence of fatal and non-fatal myocardial infarction in Denmark 1976-1998: a pooled cohort study

2003 • 110 citations

A preliminary placebo-controlled trial of selegiline hydrochloride for smoking cessation

2003 • 104 citations

Anxiolytics for smoking cessation

2000 • 103 citations

Effects of Reduced Cigarette Smoking on the Uptake of a Tobacco-Specific Lung Carcinogen

2004 • 102 citations

Tobaeco Smoking and Nicotine.

1942 • 100 citations

Advances in pharmacotherapy for tobacco dependence

2004 • 94 citations

Advances in pharmacotherapy for tobacco dependence

2004 • 90 citations

Integrating smoking cessation treatment into primary care: an effectiveness study

2004 • 89 citations

Applying genetic approaches to the treatment of nicotine dependence

2002 • 87 citations

The potential of quitlines to increase smoking cessation

2006 • 86 citations

A substitute for tobacco smoking

1973 • 84 citations

Individual differences in preferences for and responses to four nicotine replacement products

2001 • 83 citations

Smoking cessation and depression: current knowledge and future directions

2006 • 81 citations

Mecamylamine (Inversine®): an old antihypertensive with new research directions

2002 • 75 citations

Naltrexone and nicotine patch in smoking cessation: A preliminary study

2003 • 75 citations

Meta‐analytic review of the efficacy of smoking cessation interventions

1994 • 72 citations

A randomized controlled trial of oral selegiline plus nicotine skin patch compared with placebo plus nicotine skin patch for smoking cessation

2003 • 70 citations

A Randomized Trial of Nortriptyline Combined With Transdermal Nicotine for Smoking Cessation

2004 • 70 citations

Reboxetine: Attenuation of Intravenous Nicotine Self-Administration in Rats

2002 • 69 citations

Naltrexone attenuates acute cigarette smoking behavior

2003 • 67 citations

A randomized, double‐blind, placebo‐controlled clinical evaluation of a nicotine sublingual tablet in smoking cessation

2000 • 65 citations

Effects of Long-term Cigarette Smoking on the Human Locus Coeruleus

2001 • 63 citations

Transdermal nicotine patches with low-intensity support to aid smoking cessation in outpatients in a general hospital. A placebo-controlled trial

1993 • 63 citations

Efficacy and Safety of an Over-the-counter Transdermal Nicotine Patch as an Aid for Smoking Cessation

1998 • 60 citations

Reboxetine: Functional Inhibition of Monoamine Transporters and Nicotinic Acetylcholine Receptors

2002 • 60 citations

Mecamylamine does not precipitate withdrawal in cigarette smokers

1996 • 59 citations

CIRCULATORY EFFECTS OF NICOTINE AEROSOL INHALATIONS AND CIGARETTE SMOKING IN MAN

1967 • 58 citations

Discrimination of Smoking Status by Thiocyanate and Cotinine in Serum, and Carbon Monoxide in Expired Air

1992 • 56 citations

NON-NICOTINE PHARMACOTHERAPY FOR SMOKING CESSATION

1999 • 55 citations

Which smokers are helped to give up smoking using transdermal nicotine patches? Results from a randomized, double-blind, placebo-controlled trial.

1996 • 55 citations

Pharmacotherapies to enhance smoking cessation during pregnancy

2003 • 54 citations

The transdermal nicotine patch: results of a randomised placebo‐controlled trial

1994 • 52 citations

Cigar use before and after a cigarette excise tax increase in New Jersey

2004 • 49 citations

A Case Series of Nicotine Nasal Spray in the Treatment of Tobacco Dependence Among Patients With Schizophrenia

2004 • 43 citations

Glucose for Smoking Cessation

2001 • 42 citations

Bromocriptine reduces cigarette smoking

2000 • 41 citations

The Promises and Pitfalls of Reboxetine

2003 • 34 citations

Assessing internal tobacco industry knowledge of the neurobiology of tobacco dependence

2004 • 31 citations

Opioid antagonists for smoking cessation

2001 • 30 citations

The internet and the industrial revolution in smoking cessation counselling

2006 • 28 citations

Effects of the Cannabinoid-1 Receptor Blocker Rimonabant on Weight Reduction and Cardiovascular Risk Factors in Overweight Patients: 1-Year Experience From the RIO-Europe Study

2006 • 28 citations

A randomized, double-blind, placebo-controlled clinical evaluation of a nicotine sublingual tablet in smoking cessation

2000 • 21 citations

A Review of Clinical Prevention Services at Group Health Cooperative of Puget Sound

1995 • 18 citations

Acute effects of glucose tablets on craving, withdrawal symptoms, and sustained attention in 12-h abstinent tobacco smokers

2002 • 16 citations

Results of screening for excessive drinkers in four Sydney teaching hospitals

1994 • 13 citations

Conversation with Ove Fernö

1994 • 13 citations

Carbidopa/levodopa for smoking cessation: a pilot study with negative results

2000 • 11 citations

Conversation with Michael A. H. Russell

2003 • 6 citations

Conversation with Murray Jarvik

2001 • 5 citations

Deleted Work

1955 • 0 citations