Antipsychotic drugs clozapine and olanzapine upregulate bcl-2 mRNA and protein in rat frontal cortex and hippocampus

The Bcl-2 Protein Family: Arbiters of Cell Survival

1998 • 5,359 citations

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax

1994 • 1,303 citations

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

1994 • 1,106 citations

BCL-2 GENE FAMILY IN THE NERVOUS SYSTEM

1997 • 596 citations

The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis

1993 • 586 citations

Neuronal and Glial Somal Size in the Prefrontal Cortex

1998 • 530 citations

Bcl-2 promotes regeneration of severed axons in mammalian CNS

1997 • 449 citations

Neuroimaging studies of the hippocampus in schizophrenia

2001 • 399 citations

Atypical Antipsychotics: New Directions and New Challenges in the Treatment of Schizophrenia

2001 • 324 citations

Mechanisms of action of atypical antipsychotic drugs: a critical analysis

1996 • 315 citations

Lithium at 50: have the neuroprotective effects of this unique cation been overlooked?

1999 • 312 citations

Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.

1994 • 251 citations

Olanzapine

1997 • 240 citations

Expression of brain‐derived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs

2002 • 239 citations

Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography

1993 • 225 citations

Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation

1997 • 201 citations

Dose-Related Effects of Chronic Antidepressants on Neuroprotective Proteins BDNF, Bcl-2 and Cu/Zn-SOD in Rat Hippocampus

2003 • 167 citations

Cortical Bcl-2 protein expression and apoptotic regulation in schizophrenia

2000 • 163 citations

Treatment with atypical antipsychotics: new indications and new populations

2001 • 144 citations

Olanzapine protects PC12 cells from oxidative stress induced by hydrogen peroxide

2003 • 134 citations

The ability of atypical antipsychotic drugs vs. haloperidol to protect PC12 cells against MPP⁺‐induced apoptosis

2003 • 133 citations

BCL2 regulates neural differentiation.

1996 • 131 citations

The Bcl-2 gene family and apoptosis

1998 • 108 citations

Protective effects of atypical antipsychotic drugs on PC12 cells after serum withdrawal

2002 • 106 citations

Efficacy of olanzapine: an overview of pivotal clinical trials.

1997 • 102 citations

bcl-2 Messenger RNA is localized in neurons of the developing and adult rat brain

1994 • 96 citations

The effects of early and sustained intervention on the long-term morbidity of schizophrenia

1998 • 70 citations

The 5-HT1A receptor agonist Bay×3702 inhibits apoptosis induced by serum deprivation in cultured neurons

1999 • 44 citations

Stimulation of 5-HT1A receptors reduces apoptosis after transient forebrain ischemia in the rat

2000 • 37 citations

Effect of 5-hydroxytryptamine 1A receptor agonist BAY X 3702 on BCL-2 and BAX proteins level in the ipsilateral cerebral cortex of rats after transient focal ischaemia

2001 • 20 citations