Cytokines in pancreatic carcinoma

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1997 • 4,661 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

Interleukin-6 family of cytokines and gp130

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Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes.

1992 • 1,259 citations

Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease

1989 • 870 citations

The balance between IL-1 and IL-1Ra in disease

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Interleukin-8 and human cancer biology

2001 • 679 citations

Evidence for the involvement of interleukin 6 in experimental cancer cachexia.

1992 • 648 citations

The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells.

1999 • 640 citations

Interleukin-6 in human multiple myeloma

1995 • 550 citations

Ly‐1 B (B‐1) cells are the main source of B cell‐derived interleukin 10

1992 • 525 citations

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1991 • 514 citations

Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells.

1990 • 487 citations

Cytokines, the Acute-Phase Response, and Resting Energy Expenditure in Cachectic Patients with Pancreatic Cancer

1994 • 415 citations

Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute-phase proteins.

1992 • 373 citations

Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10

1990 • 347 citations

Serum interleukin‐6 levels reflect the disease status of colorectal cancer

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Interleukin-6: A candidate mediator of human prostate cancer morbidity

1995 • 293 citations

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1992 • 247 citations

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1993 • 239 citations

Phase I trial of subcutaneous interleukin-6 in patients with advanced malignancies.

1993 • 223 citations

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1991 • 214 citations

Chinese Hamster Ovarian Cells Transfected with the Murine lnterleukin-6 Gene cause Hypercalcemia as well as Cachexia, Leukocytosis and Thrombocytosis in Tumor-Bearing Nude Mice

1991 • 207 citations

Serum interleukin 6 levels are elevated in lymphoma patients and correlate with survival in advanced Hodgkin's disease and with B symptoms.

1993 • 169 citations

Serum interleukin-6 levels correlate with prognosis in diffuse large-cell lymphoma.

1995 • 167 citations

IL-10 production is enhanced in human T cells by IL-12 and IL-6 and in monocytes by tumor necrosis factor-alpha.

1996 • 163 citations

A possible autocrine role for interleukin-6 in two lymphoma cell lines

1989 • 162 citations

Interleukin 6 gene expression in normal and neoplastic B cells.

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1991 • 145 citations

Elevated Serum Interleukin-6 Levels in Patients with Pancreatic Cancer

1998 • 140 citations

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1991 • 139 citations

Comparison of Serum Interleukin-10 (IL-10) Levels Between Normal Volunteers and Patients with Advanced Melanoma

2001 • 129 citations

Interleukin-6 is a prognostic factor in multiple myeloma [letter] [see comments]

1991 • 120 citations

Interleukin-6 is pyrogenic but not somnogenic

1989 • 114 citations

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1993 • 109 citations

Prognostic Value of Serum Interleukin-6 in Diffuse Large-cell Lymphoma

1997 • 108 citations

Expression of an exogenous interleukin 6 gene in human Epstein Barr virus B cells confers growth advantage and in vivo tumorigenicity.

1990 • 105 citations

Suppression of chronic myelogenous leukemia colony growth by interleukin-1 (IL-1) receptor antagonist and soluble IL-1 receptors: a novel application for inhibitors of IL-1 activity

1991 • 95 citations

Clinical implications of interleukin (IL)-10 induced by non-small-cell lung cancer

2000 • 92 citations

Interleukin-10 in Non-Hodgkin's Lymphoma

1997 • 92 citations

Clinical Correlates of Elevated Serum Levels of Interleukin-6 in Patients with Untreated Hodgkin's Disease

1997 • 83 citations

Inhibition of acute myelogenous leukemia blast proliferation by interleukin-1 (IL-1) receptor antagonist and soluble IL-1 receptors

1992 • 78 citations

Peripheral blood cells from weight-losing cancer patients control the hepatic acute phase response by a primarily interleukin-6 dependent mechanism.

1999 • 70 citations

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1994 • 65 citations

Circulating Levels of Interleukin-10 and Interleukin-6 in Gastric and Colon Cancer Patients Before and After Surgery: Relationship with Radicality and Outcome

2002 • 64 citations

Long-Term Consequences of Interleukin-6 Overexpression in Transgenic Mice

1992 • 60 citations

New perspectives in the management of pancreas cancer

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1995 • 52 citations

High Serum Interleukin-6 Levels Correlate with a Shorter Failure-Free Survival in Indolent Lymphoma

1998 • 51 citations

Association of the 323/A3 surface glycoprotein with tumor characteristics and behavior in human breast cancer.

1990 • 45 citations

Increased levels of circulating interleukin‐6 in patients with hodgkin's disease

1991 • 34 citations

Cytokine production by CAPAN-1 and CAPAN-2 cell lines.

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1995 • 17 citations

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Molecular genetics and therapy of leukemia

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