Elevated Serum Interleukin-6 Levels in Patients with Pancreatic Cancer

Cancer: Principles and Practice of Oncology.

1991 • 8,402 citations

The biology of interleukin-6

1989 • 1,964 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

The biology of interleukin-6

1989 • 1,459 citations

Clinical Cancer Research

1941 • 1,358 citations

Increased plasma levels of interleukin-6 in sepsis [see comments]

1989 • 813 citations

Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6

1989 • 775 citations

Evidence for the involvement of interleukin 6 in experimental cancer cachexia.

1992 • 648 citations

Long-Term Survival After Resection for Ductal Adenocarcinoma of the Pancreas Is It Really Improving?

1995 • 597 citations

Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias.

1989 • 501 citations

Interleukin 6: A Multifunctional Cytokine Regulating Immune Reactions and the Acute Phase Protein Response

1990 • 483 citations

Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia

1991 • 419 citations

Survival after resection for ductal adenocarcinoma of the pancreas

1996 • 372 citations

Role of interleukin-6 in mediating the acute phase protein response and potential as an early means of severity assessment in acute pancreatitis.

1993 • 289 citations

Serum interleukin-6 levels correlate with disease status in patients with epithelial ovarian cancer

1991 • 214 citations

Serum interleukin-6, interleukin-8, andβ 2-Microglobulin in early assessment of severity of acute pancreatitis comparison with serum C-reactive protein

1995 • 208 citations

Serum interleukin 6 levels are elevated in lymphoma patients and correlate with survival in advanced Hodgkin's disease and with B symptoms.

1993 • 169 citations

Severe cachexia in mice inoculated with interferon‐γ‐producing tumor cells

1991 • 156 citations

Interleukin-6 is a prognostic factor in multiple myeloma [letter] [see comments]

1991 • 145 citations

Cancer cachexia syndrome developed in nude mice bearing melanoma cells producing leukemia-inhibitory factor.

1991 • 137 citations

Interleukin-6 is a prognostic factor in multiple myeloma [letter] [see comments]

1991 • 120 citations

Serum levels of cytokines in patients with untreated primary lung cancer

1996 • 92 citations

Endogenous interleukin 6 levels in patients with metastatic malignant melanoma: correlation with tumor burden.

1996 • 71 citations

Murine Tumor Cells Metastasizing Selectively in the Liver: Ability to Produce Hepatocyte‐activating Cytokines Interleukin‐1 and/or ‐6

1991 • 57 citations

Plasma cytokine levels and monocyte activation in patients with obstructive jaundice

1996 • 42 citations