Long-term morphine treatment decreases endorphin levels in rat brain and pituitary

Common precursor to corticotropins and endorphins

1977 • 1,106 citations

High-affinity enkephalin-degrading peptidase in brain is increased after morphine

1978 • 652 citations

Opioid Peptides Endorphins in Pituitary and Brain

1976 • 518 citations

Heroin Addiction—A Metabolic Disease

1967 • 338 citations

Characteristics and function of opioids

1979 • 283 citations

Effects of Purified Hypothalamic Corticotropin-Releasing Factor and Other Substances on the Secretion of Adrenocorticotropin and β-Endorphin-Like Immunoactivities inVitro*

1978 • 179 citations

Radioimmunoassay of β-endorphin basal and stimulated levels in extracted rat plasma

1978 • 147 citations

Radioimmunoassay of brain peptides: Evaluation of a methodology for the assay of β-endorphin and enkephalin

1977 • 140 citations

Stability of Met-enkephalin content in brain structures of morphine-dependent or foot shock-stressed rats

1977 • 139 citations

β-Endorphin-like immunoreactivity in plasma, pituitaries and hypothalamus of rats following treatment with opiates

1978 • 116 citations

Radioimmunoassay of enkephalins

1977 • 98 citations

Enkephalin: Radioimmunoassay and radioreceptor assay in morphine dependent rats

1977 • 88 citations

Distribution of methionine- and leucine-enkephalin within the rat pituitary gland measured by highly specific radioimmunoassays

1978 • 87 citations

Modulation of in vitro release of β-endorphin from the separate lobes of the rat pituitary

1979 • 72 citations

Non-competitive nature of the antagonistic mechanism responsible for tolerance development to opiate-induced analgesia

1979 • 36 citations