Selective oestrogen receptor modulators: potential therapeutic applications

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

1997 • 4,422 citations

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 • 3,285 citations

Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52 705 women with breast cancer and 108 411 women without breast cancer

1997 • 2,438 citations

Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 Sites

1997 • 1,808 citations

Effects of Raloxifene on Bone Mineral Density, Serum Cholesterol Concentrations, and Uterine Endometrium in Postmenopausal Women

1997 • 1,641 citations

The Use of Estrogens and Progestins and the Risk of Breast Cancer in Postmenopausal Women

1995 • 1,532 citations

Postmenopausal Estrogen and Progestin Use and the Risk of Cardiovascular Disease

1996 • 1,323 citations

Postmenopausal Hormone Therapy and Mortality

1997 • 1,184 citations

A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease

1997 • 965 citations

LONG-TERM PREVENTION OF POSTMENOPAUSAL OSTEOPOROSIS BY ŒSTROGEN

1976 • 946 citations

Risk of venous thromboembolism in users of hormone replacement therapy

1996 • 827 citations

Long-Term Estrogen Replacement Therapy Prevents Bone Loss and Fractures

1985 • 788 citations

Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats.

1994 • 614 citations

Mouse Estrogen Receptor β Forms Estrogen Response Element-Binding Heterodimers with Estrogen Receptor α

1997 • 610 citations

Risk of hospital admission for idiopathic venous thromboembolism among users of postmenopausal oestrogens

1996 • 606 citations

Risk of endometrial cancer in relation to use of oestrogen combined with cyclic progestagen therapy in postmenopausal women

1997 • 450 citations

Identification of an Estrogen Response Element Activated by Metabolites of 17β-Estradiol and Raloxifene

1996 • 432 citations

The novel estrogen receptor‐β subtype: potential role in the cell‐ and promoter‐specific actions of estrogens and anti‐estrogens

1997 • 406 citations

A controlled trial of raloxifene (LY139481) HCl: Impact on bone turnover and serum lipid profile in healthy postmenopausal women

1996 • 362 citations

Hormone replacement therapy and risk of venous thromboembolism: population based case-control study

1997 • 349 citations

Mouse Estrogen Receptor Forms Estrogen Response Element-Binding Heterodimers with Estrogen Receptor

1997 • 203 citations

Raloxifene preserves bone strength and bone mass in ovariectomized rats.

1994 • 165 citations

The effects of raloxifene on tibia histomorphometry in ovariectomized rats

1994 • 136 citations

Dual-energy X-ray absorptiometry of raloxifene effects on the lumbar vertebrae and femora of ovariectomized rats

1994 • 104 citations

A pharmacological review of raloxifene

1996 • 73 citations

7 Hormone replacement therapy

1997 • 17 citations

Tamoxifen: oestrogen or anti-oestrogen in bone?

1995 • 9 citations