The “Bystander Effect”: Association of U-87 Cell Death with Ganciclovir-Mediated Apoptosis of Nearby Cells and Lack of Effect in Athymic Mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

1992 • 1,530 citations

Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection.

1990 • 1,465 citations

Cell death and control of cell survival in the oligodendrocyte lineage

1992 • 1,331 citations

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

1993 • 1,097 citations

Gap junctions: New tools, new answers, new questions

1991 • 981 citations

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy.

1986 • 962 citations

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

1987 • 881 citations

Connexin family of gap junction proteins

1990 • 553 citations

Curability of Tumors Bearing Herpes Thymidine Kinase Genes Transfered by Retroviral Vectors

1990 • 514 citations

In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats.

1993 • 442 citations

In VitroEvidence That Metabolic Cooperation Is Responsible for the Bystander Effect Observed with HSVtkRetroviral Gene Therapy

1993 • 425 citations

Gap junctions in cultured astrocytes: Single-channel currents and characterization of channel-forming protein

1991 • 360 citations

Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: an innovative approach for cancer therapy.

1991 • 315 citations

Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors.

1994 • 302 citations

Lymphoma Regression Induced by Ganciclovir in Mice Bearing a Herpes Thymidine Kinase Transgene

1990 • 208 citations

Gene therapy of maliganant brain tumors: A rat glioma line bearing the herpes simplex virus type 1‐thymidine kinase gene and wild type retrovirus kills other tumor cells

1992 • 170 citations

Thymidine kinase-mediated killing of rat brain tumors

1993 • 136 citations

Gene therapy of rat 9L gliosarcoma tumors by transduction with selectable genes does not require drug selection.

1994 • 97 citations

Intercellular communication may facilitate apoptosis: Implications for tumor promotion

1994 • 94 citations

In vivo transfer of the human interleukin-2 gene: negative tumoricidal results in experimental brain tumors

1994 • 87 citations

Is the gap junction channel - The Connexon - made of connexin or ductin?

1993 • 46 citations