Transforming Growth Factor-α Stimulates Proto-Oncogene c-junExpression and a Mitogenic Program in Primary Cultures of Adult Rat Hepatocytes

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Growth factors from murine sarcoma virus-transformed cells.

1978 • 1,457 citations

Role of ion flux in the control of c-fos expression

1986 • 1,006 citations

Cell migration is essential for sustained growth of keratinocyte colonies: The roles of transforming growth factor-α and epidermal growth factor

1987 • 703 citations

FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA

1982 • 668 citations

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

1988 • 578 citations

Cloning and sequence analysis of a cDNA for rat transforming growth factor-α

1985 • 388 citations

Increased sodium ion influx is necessary to initiate rat hepatocyte proliferation

1979 • 376 citations

The epidermal growth factor receptor as a multifunctional allosteric protein

1988 • 286 citations

Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions.

1983 • 273 citations

Epidermal growth factor-like transforming growth factor. I. Isolation, chemical characterization, and potentiation by other transforming factors from feline sarcoma virus-transformed rat cells.

1983 • 266 citations

A point mutation at the ATP-binding site of the EGF-receptor abolishes signal transduction.

1988 • 215 citations

Proto-oncogene expression in regenerating liver is simulated in cultures of primary adult rat hepatocytes.

1986 • 167 citations

Procarcinogen activation and hormonal control of cell proliferation in differentiated primary adult rat liver cell cultures

1977 • 143 citations

Acetaldehyde increases collagen gene transcription in cultured human fibroblasts.

1987 • 143 citations

Elevation of transforming growth factor alpha and its relationship to the epidermal growth factor and alpha-fetoprotein levels in patients with hepatocellular carcinoma.

1987 • 129 citations

GROWTH CONTROL OF DIFFERENTIATED FETAL RAT HEPATOCYTES IN PRIMARY MONOLAYER CULTURE

1974 • 127 citations

Sarcoma growth factor (SGF): Specific binding to epidermal growth factor (EGF) membrane receptors

1980 • 123 citations

[47] Liver cells

1979 • 120 citations

GROWTH CONTROL OF DIFFERENTIATED ADULT RAT HEPATOCYTES IN PRIMARY CULTURE*

1980 • 119 citations

Characterization of high molecular weight transforming growth factor .alpha. produced by rat hepatocellular carcinoma cells

1988 • 107 citations

c-fos and c-myc gene activation, ionic signals, and DNA synthesis in thymocytes.

1986 • 104 citations

Rat hepatocyte proliferation is stimulated by insulin-like peptides in defined medium

1982 • 52 citations

GROWTH CONTROL OF DIFFERENTIATED FETAL RAT HEPATOCYTES IN PRIMARY MONOLAYER CULTURE

1974 • 46 citations

Stimulation of DNA and Protein Synthesis in Fetal-Rat Liver Cells by Serum from Partially Hepatectomized Rats

1972 • 45 citations

Proliferation of Hepatocytes

1978 • 43 citations

Ionic landmarks along the mitogenic route

1979 • 35 citations

Transforming growth factor alpha (TGFα) induction of c-fos and c-myc expression in C3H 10Tl/2 cells

1988 • 25 citations

Selective Effects of Portal Blood Diversion and Glucagon on Rat Hepatocyte Rates of S-Phase Entry and Deoxyribonucleic Acid Synthesis*

1983 • 13 citations

Expression of the insulinoma gene rig during liver regeneration and in primary cultured hepatocytes

1988 • 12 citations