Phosphorylation of Myosin Regulatory Light Chains by the Molluscan Twitchin Kinase

Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase.

1987 • 503 citations

Sequence of an unusually large protein implicated in regulation of myosin activity in C. elegans

1989 • 368 citations

Towards a molecular understanding of titin.

1992 • 338 citations

Structure of the regulatory domain of scallop myosin at 2.8 Ä resolution

1994 • 296 citations

Internal protein sequence analysis: Enzymatic digestion for less than 10 μg of protein bound to polyvinylidene difluoride or nitrocellulose membranes

1992 • 290 citations

Titin and nebulin: protein rulers in muscle?

1994 • 202 citations

Insights into autoregulation from the crystal structure of twitchin kinase

1994 • 192 citations

Activation mechanisms for Ca2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase.

1994 • 150 citations

Selective purification of the 20,000-Da light chains of smooth muscle myosin

1983 • 129 citations

Sequence analysis of mutations that affect the synthesis, assembly and enzymatic activity of the unc-54 myosin heavy chain of Caenorhabditis elegans

1985 • 129 citations

[10] Design and use of peptide substrates for protein kinases

1991 • 125 citations

Additional sequence complexity in the muscle gene, unc-22, and its encoded protein, twitchin, of Caenorhabditis elegans.

1993 • 116 citations

Spatial requirements for location of basic residues in peptide substrates for smooth muscle myosin light chain kinase.

1985 • 88 citations

Mini-titins in striated and smooth molluscan muscles: structure, location and immunological crossreactivity

1993 • 85 citations

A protein activator of Ca(2+)-calmodulin-dependent protein kinase Ia.

1994 • 80 citations

cAMP-dependent phosphorylation of Aplysia twitchin may mediate modulation of muscle contractions by neuropeptide cotransmitters.

1994 • 69 citations

Autophosphorylation of molluscan twitchin and interaction of its kinase domain with calcium/calmodulin.

1994 • 61 citations

Cellular titin localization in stress fibers and interaction with myosin II filaments in vitro.

1994 • 52 citations

Protein kinase domain of twitchin has protein kinase activity and an autoinhibitory region.

1994 • 49 citations

Rod phosphorylation favors folding in a catch muscle myosin.

1987 • 49 citations

Both synchronous and asynchronous muscle isoforms of projectin (the Drosophila bent locus product) contain functional kinase domains.

1995 • 48 citations

Structural requirement of the regulatory light chain of smooth muscle myosin as a substrate for myosin light chain kinase.

1994 • 40 citations

Structural requirements for phosphorylation of myosin regulatory light chain from smooth muscle.

1994 • 32 citations

[16] Identification of phosphorylation sites in peptides using a microsequencer

1991 • 15 citations