Effect of Delayed Administration of U74006F (Tirilazad Mesylate) on Recovery of Locomotor Function After Experimental Spinal Cord Injury

A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

1990 • 2,629 citations

Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation.

1987 • 474 citations

Effects of the 21-aminosteroid U74006F on experimental head injury in mice

1988 • 296 citations

21-Aminosteroid lipid peroxidation inhibitor U74006F protects against cerebral ischemia in gerbils.

1988 • 266 citations

Evaluation of an intensive methylprednisolone sodium succinate dosing regimen in experimental spinal cord injury

1987 • 195 citations

The 21-aminosteroid inhibitors of lipid peroxidation: Reactions with lipid peroxyl and phenoxy radicals

1989 • 187 citations

Effects of the 21-aminosteroid U74006F on posttraumatic spinal cord ischemia in cats

1988 • 176 citations

Effects of treatment with U-74006F on neurological outcome following experimental spinal cord injury

1988 • 160 citations

Attenuation of postischemic cerebral hypoperfusion by the 21-aminosteroid U74006F.

1988 • 139 citations

A new 21-aminosteroid antioxidant lacking glucocorticoid activity stimulates adrenocorticotropin secretion and blocks arachidonic acid release from mouse pituitary tumor (AtT-20) cells.

1988 • 138 citations

21-Aminosteroid reduces ion shifts and edema in the rat middle cerebral artery occlusion model of regional ischemia.

1988 • 135 citations

Correlation Between Attenuation of Posttraumatic Spinal Cord Ischemia and Preservation of Tissue Vitamin E by the 21-Aminosteroid U74006F: Evidence for anIn VivoAntioxidant Mechanism

1989 • 120 citations

Effect of the 21-aminosteroid U-74006F on cerebral vasospasm following subarachnoid hemorrhage

1989 • 111 citations

Protective effect of a 21-aminosteroid on the blood-brain barrier following subarachnoid hemorrhage in rats.

1989 • 103 citations

Effect of the aminosteroid U74006F after cardiopulmonary arrest in dogs.

1988 • 100 citations

A Trial of the 21-Aminosteroid U74006F in a Primate Model of Chronic Cerebral Vasospasm

1989 • 99 citations

Spinal cord energy metabolism following compression trauma to the feline spinal cord

1980 • 97 citations

Inhibition of arachidonic acid-induced vasogenic brain edema by the non-glucocorticoid 21-aminosteroid U74006F

1988 • 80 citations

Effect of the nonglucocorticoid 21-aminosteroid u74006f on experimental cerebral vasospasm

1989 • 77 citations

Pretreatment with Alpha Tocopherol Enhances Neurologic Recovery After Experimental Spinal Cord Compression Injury

1988 • 72 citations

Cerebrospinal fluid lactate and electrolyte levels following experimental spinal cord injury

1976 • 61 citations

Effects of the nonglucocorticoid 21-aminosteroid U74006F on acute cerebral hypoperfusion following experimental subarachnoid hemorrhage

1988 • 60 citations

Protection against postischemic spinal cord injury using a new 21-aminosteroid

1990 • 57 citations

Preservation of motor nerve function during early degeneration by the 21-aminosteroid anti-oxidant U74006F

1990 • 18 citations