Effects of treatment with U-74006F on neurological outcome following experimental spinal cord injury

Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids

1980 • 925 citations

A phospholipase A2 inhibitory protein in rabbit neutrophils induced by glucocorticoids.

1980 • 841 citations

The free radical pathology and the microcirculation in the major central nervous system disorders.

1980 • 660 citations

Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation.

1987 • 474 citations

Goodman and Gilman's The Pharmacological Basis of Therapeutics.

1981 • 339 citations

Effect of high-dose corticosteroid therapy on blood flow, evoked potentials, and extracellular calcium in experimental spinal injury

1982 • 319 citations

Effects of the 21-aminosteroid U74006F on experimental head injury in mice

1988 • 296 citations

Mechanism of calcium potentiation of oxygen free radical injury to renal mitochondria. A model for post-ischemic and toxic mitochondrial damage.

1986 • 258 citations

Effects of intravenous methylprednisolone on spinal cord lipid peroxidation and (Na+ + K+)-ATPase activity

1982 • 249 citations

Glucocorticoid mechanisms in acute spinal cord injury: A review and therapeutic rationale

1982 • 239 citations

A pharmacological analysis of the pathophysiological mechanisms of posttraumatic spinal cord ischemia

1986 • 228 citations

High-dose glucocorticoid treatment improves neurological recovery in head-injured mice

1985 • 219 citations

Lipid Hydrolysis and Peroxidation in Injured Spinal Cord: Partial Protection with Methylprednisolone or Vitamin E and Selenium

1985 • 206 citations

Correlation of methylprednisolone levels in cat spinal cord with its effects on (Na+ + K+)-ATPase, lipid peroxidation, and alpha motor neuron function

1982 • 201 citations

Effect of methylprednisolone in compression trauma to the feline spinal cord

1981 • 196 citations

Evaluation of an intensive methylprednisolone sodium succinate dosing regimen in experimental spinal cord injury

1987 • 195 citations

Effects of a single large dose of methylprednisolone sodium succinate on experimental posttraumatic spinal cord ischemia

1984 • 193 citations

Further studies on free-radical pathology in the major central nervous system disorders: effect of very high doses of methylprednisolone on the functional outcome, morphology, and chemistry of experimental spinal cord impact injury

1982 • 187 citations

Effects of the 21-aminosteroid U74006F on posttraumatic spinal cord ischemia in cats

1988 • 176 citations

Membrane lipid changes in laminectomized and traumatized cat spinal cord.

1985 • 166 citations

Lipid Peroxidation‐Induced Inhibition of γ‐Aminobutyric Acid Uptake in Rat Brain Synaptosomes: Protection by Glucocorticoids

1985 • 161 citations

Lactate and pyruvate metabolism in injured cat spinal cord before and after a single large intravenous dose of methylprednisolone

1983 • 158 citations

Alteration of thrornboxane and prostacyclin levels in experimental spinal cord injury

1985 • 148 citations

Current application of “high-dose” steroid therapy for CNS injury

1985 • 147 citations

A new 21-aminosteroid antioxidant lacking glucocorticoid activity stimulates adrenocorticotropin secretion and blocks arachidonic acid release from mouse pituitary tumor (AtT-20) cells.

1988 • 138 citations

Inhibition of Na+-K+-activated ATPase activity following experimental spinal cord trauma

1978 • 110 citations

Molecular Aspects of Membrane Structure in Cerebral Edema

1972 • 101 citations

A nonglucocorticoid steroid analog of methylprednisolone duplicates its high-dose pharmacology in models of central nervous system trauma and neuronal membrane damage.

1987 • 98 citations

Spinal cord energy metabolism following compression trauma to the feline spinal cord

1980 • 97 citations

Spinal cord injury and protection

1985 • 90 citations

Iron-induced lipid peroxidation in spinal cord: Protection with mannitol and methylprednisolone

1985 • 86 citations

Altered levels of PGF in cat spinal cord tissue following traumatic injury

1976 • 84 citations

Calcium Enhances In Vitro Free Radical‐Induced Damage to Brain Synaptosomes, Mitochondria, and Cultured Spinal Cord Neurons

1985 • 78 citations

A comparative study of steroid therapy in acute experimental spinal cord injury.

1980 • 77 citations

Interaction of Lipid Peroxidation and Calcium in the Pathogenesis of Neuronal Injury

1985 • 75 citations

Role of monoamines in experimental spinal cord injury in rats

1985 • 71 citations

Cerebrospinal fluid lactate and electrolyte levels following experimental spinal cord injury

1976 • 61 citations

CORTICOSTEROID (METHYLPREDNISOLONE) MODULATION OF PHOTOPEROXIDATION BY ULTRAVIOLET LIGHT IN LIPOSOMES

1979 • 60 citations

PARAMAGNETIC SPECIES AND RADICAL PRODUCTS IN CAT SPINAL CORD *

1973 • 41 citations

The Effects of Large Doses of Methylprednisolone on Neurologic Recovery and Survival in the Mongolian Gerbil Following Three Hours of Unilateral Carotid Occlusion

1986 • 24 citations

A new class of compounds for stroke and trauma: effects of 21-aminosteroids on lipid peroxidation.

1987 • 24 citations