Chimeric G Proteins Allow a High-Throughput Signaling Assay of Gi-Coupled Receptors

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1985 • 7,054 citations

Goodman and Gilman's the Pharmacological Basis of Therapeutics

1986 • 6,964 citations

G Protein-coupled Receptors

1998 • 1,292 citations

STRUCTURE AND FUNCTION OF G PROTEIN-COUPLED RECEPTORS

1994 • 1,070 citations

ORL1, a novel member of the opioid receptor family

1994 • 1,060 citations

Substitution of three amino acids switches receptor specificity of Gqα to that of Giα

1993 • 702 citations

The cytosensor microphysiometer: biological applications of silicon technology

1992 • 631 citations

The melanocortin receptors: agonists, antagonists, and the hormonal control of pigmentation.

1996 • 513 citations

Gα15 and Gα16 Couple a Wide Variety of Receptors to Phospholipase C

1995 • 488 citations

DNA Binding Specificities and Pairing Rules of the Ah Receptor, ARNT, and SIM Proteins

1995 • 388 citations

Bremazocine: A potent, long-acting opiate kappa-agonist

1980 • 314 citations

Receptor-effector coupling by G proteins: implications for normal and abnormal signal transduction

1992 • 290 citations

Human μ opiate receptor

1994 • 286 citations

The cloned μ, δ and κ receptors and their endogenous ligands: Evidence for two opioid peptide recognition cores

1995 • 263 citations

Controlling signaling with a specifically designed G _i -coupled receptor

1998 • 240 citations

Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation.

1995 • 204 citations

A Bioluminescent Assay for Agonist Activity at Potentially Any G-Protein-Coupled Receptor

1997 • 201 citations

Differential Regulation of G-protein-mediated Signaling by Chemokine Receptors

1996 • 195 citations

G alpha 13 stimulates Na-H exchange.

1994 • 175 citations

Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation.

1996 • 171 citations

The Encyclopedia of Molecular Biology

1994 • 139 citations

Identification of a human delta opioid receptor: Cloning and expression

1994 • 125 citations

Pharmacology of muscarinic acetylcholine receptor subtypes (m1–m5): high throughput assays in mammalian cells

1996 • 115 citations

Pharmacology of Muscarinic Receptor Subtypes Constitutively Activated by G Proteins

1997 • 111 citations

Coupling of metabotropic glutamate receptors 2 and 4 to G alpha 15, G alpha 16, and chimeric G alpha q/i proteins: characterization of new antagonists.

1996 • 105 citations

Cloning of a human κ opioid receptor from the brain

1995 • 100 citations

Differential Coupling of μ‐, δ‐, and κ‐Opioid Receptors to Gα₁₆‐Mediated Stimulation of Phospholipase C

1998 • 87 citations

Molecular Mechanisms Involved in Muscarinic Acetylcholine Receptor-mediated G Protein Activation Studied by Insertion Mutagenesis

1996 • 77 citations

[6] Gi assays in transfected cells

1994 • 63 citations

Induction of NFAT-mediated Transcription by Gq-coupled Receptors in Lymphoid and Non-lymphoid Cells

1996 • 63 citations

Heregulin Activation of Extracellular Acidification in Mammary Carcinoma Cells Is Associated with Expression of HER2 and HER3

1995 • 47 citations

A novel system that reports the G‐proteins linked to a given receptor: a study of type 3 somatostatin receptor

1997 • 36 citations

Interactions of Muscarinic Receptors with the Heterotrimeric G Proteins G_q and G₁₂: Transduction of Proliferative Signals

1997 • 21 citations