Developing novel treatments for mood disorders: accelerating discovery
Data up to Jan 2025
Total Citations Per Year
Abstract
References (82)
The Corticosteroid Receptor Hypothesis of Depression
2000 • 2,126 citations
A Molecular and Cellular Theory of Depression
1997 • 2,091 citations
Neuroimaging studies of mood disorders
2000 • 1,303 citations
Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors
1998 • 1,067 citations
A Double-Blind Placebo-Controlled Study of Lamotrigine Monotherapy in Outpatients With Bipolar I Depression
1999 • 1,056 citations
Complex promoter and coding region β 2 -adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness
2000 • 971 citations
Selective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-analysis of efficacy and tolerability
2000 • 937 citations
Pharmacological profile of antidepressants and related compounds at human monoamine transporters
1997 • 906 citations
Pharmacogenetics and the practice of medicine
2000 • 822 citations
Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors
2001 • 818 citations
DEFINITION AND EPIDEMIOLOGY OF TREATMENT-RESISTANT DEPRESSION
1996 • 764 citations
Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated
2000 • 698 citations
Transient Acute Depression Induced by High-Frequency Deep-Brain Stimulation
1999 • 656 citations
Effects of SSRIs on Sexual Function
1999 • 652 citations
Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
1998 • 605 citations
Antidepressant-induced mania and cycle acceleration: a controversy revisited
1995 • 600 citations
Textbook of psychopharmacology
1975 • 583 citations
Neurobiology of Mental Illness
2011 • 532 citations
The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders
1999 • 498 citations
Initiation and adaptation: a paradigm for understanding psychotropic drug action
1996 • 489 citations
Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines
1997 • 446 citations
Higher Than Normal Plasma Interleukin-6 Concentrations in Cancer Patients With Depression: Preliminary Findings
2001 • 441 citations
Resistance to antidepressant medications and short-term clinical response to ECT
1996 • 427 citations
Allelic Variation in the Serotonin Transporter Promoter Affects Onset of Paroxetine Treatment Response in Late-Life Depression
2000 • 410 citations
Serotonin transporter gene polymorphism and antidepressant response
2000 • 392 citations
Phosphorylation and Sequestration of Serotonin Transporters Differentially Modulated by Psychostimulants
1999 • 387 citations
Effectiveness of St John's Wort in Major Depression
2001 • 380 citations
Neurobiology of Mental Illness.
2000 • 344 citations
Trazodone
1994 • 325 citations
The pharmacologic profile of mirtazapine.
1996 • 325 citations
Parallel Genotyping of Human SNPs Using Generic High-density Oligonucleotide Tag Arrays
2000 • 309 citations
A double-blind trial of bupropion versus desipramine for bipolar depression.
1994 • 281 citations
Rapid Reversal of Psychotic Depression Using Mifepristone
2001 • 274 citations
Regional Cerebral Blood Flow in Mood Disorders, III
1994 • 261 citations
A corticosteroid/dopamine hypothesis for psychotic depression and related states
1985 • 244 citations
Cocaine and Antidepressant-Sensitive Biogenic Amine Transporters Exist in Regulated Complexes with Protein Phosphatase 2A
2000 • 234 citations
The Anticonvulsant Hypothesis of the Mechanisms of Action of ECT
1999 • 231 citations
Reboxetine: the first selective noradrenaline re-uptake inhibitor
2000 • 211 citations
Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins
1998 • 187 citations
Complementary Therapies for Depression
1998 • 174 citations
Comparison of Bifrontal and Bitemporal ECT for Major Depression
2000 • 170 citations
The Role of Serotonin Transporter Protein Gene in Antidepressant-Induced Mania in Bipolar Disorder
2001 • 159 citations
Antidepressants: past, present and future
2000 • 150 citations
Pharmacokinetics and Safety of Duloxetine, a Dual‐Serotonin and Norepinephrine Reuptake Inhibitor
2000 • 147 citations
Regional cerebral blood flow in mood disorders
1997 • 143 citations
Therapeutic advantage of bifrontal electrode placement in ECT
1993 • 137 citations
Genotyping:The predictive power of haplotypes in clinical response
2000 • 134 citations
The use of antidepressant drugs in patients with heart disease.
1998 • 128 citations
Mirtazapine Substitution in SSRI-Induced Sexual Dysfunction
2000 • 125 citations
Neurokinin1 Receptor Antagonists as Potential Antidepressants
2001 • 113 citations
Reemergence of Sexual Dysfunction in Patients With Major Depressive Disorder
2001 • 109 citations
Short-Term Augmentation of Fluoxetine With Clonazepam in the Treatment of Depression: A Double-Blind Study
1998 • 103 citations
A double-blind crossover trial of imipramine and phenelzine for outpatients with treatment-refractory depression
1993 • 102 citations
Consent and privacy in pharmacogenetic testing
2001 • 98 citations
Neurochemical Individuality
2000 • 98 citations
Physical properties and quantification of the ECT stimulus: I. Basic principles.
1994 • 94 citations
Electrode placement in ECT: cognitive effects
1990 • 86 citations
Endogenous Anticonvulsant Substance in Rat Cerebrospinal Fluid After a Generalized Seizure
1985 • 81 citations
Venlafaxine: A novel antidepressant that has a dual mechanism of action
1996 • 80 citations
Applications of biochip and microarray systems in pharmacogenomics
2000 • 79 citations
A theory of convulsive therapy in endogenous depression: Significance of hypothalamic functions
1980 • 72 citations
A SNPshot: pharmacogenetics and the future of drug therapy
2000 • 71 citations
Prophylactic efficacy of phenelzine and imipramine in chronic atypical depression: likelihood of recurrence on discontinuation after 6 months' remission
1997 • 71 citations
Augmentation strategies in patients with refractory depression
1996 • 70 citations
ECT seizure therapeutic adequacy.
1994 • 63 citations
Dosage, Seizure Threshold, and the Antidepressant Efficacy of Electroconvulsive Therapy
1986 • 61 citations
Paroxetine binding to the rat norepinephrine transporter in vivo
2000 • 61 citations
[Treatment of depression].
1960 • 59 citations
Diencephalic Stimulation and the Effects of Ect in Endogenous Depression
1976 • 57 citations
CYP2D6 Genotyping with Oligonucleotide Microarrays and Nortriptyline Concentrations in Geriatric Depression
2001 • 57 citations
Imaging serotonergic neurotransmission in depression: hippocampal pathophysiology may mirror global brain alterations
2000 • 50 citations
Asymmetric Bilateral Right Frontotemporal Left Frontal Stimulus Electrode Placement for Electroconvulsive Therapy
1994 • 45 citations
Glutamate—Hypothalamic-Pituitary-Adrenal Axis Interactions: Implications for Mood and Anxiety Disorders
2001 • 43 citations
Management of the depressive component of bipolar disorder
1996 • 32 citations
The serotonergic antidepressant nefazodone inhibits the serotonin transporter: In vivo and ex vivo studies
1995 • 31 citations
Yohimbine augmentation of fluvoxamine in refractory depression: A single-blind study
1995 • 31 citations
Absence of neuroleptic-induced parkinsonism in psychotic patients receiving adjunctive electroconvulsive therapy.
1994 • 17 citations
The effect of somatic treatment and comorbidity on immediate outcome in manic patients
1989 • 16 citations
Unilateral ECT: Medications and Monitoring
1989 • 2 citations
Positron‐Emission Tomography Tracers as Intellectual Property
2001 • 2 citations
Positron-Emission Tomography Tracers as Intellectual Property
2001 • 1 citations
Deleted Work
1955 • 0 citations