A Novel Stimulus, Oncogene, Induces Expression of CD80 (B7-1) Gene

A Theory of Self-Nonself Discrimination

1970 • 1,700 citations

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

1995 • 1,695 citations

Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE

1995 • 326 citations

CD28-B7 interactions in T-cell activation

1994 • 315 citations

B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt's lymphomas.

1982 • 297 citations

Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts.

1986 • 272 citations

Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells.

1992 • 220 citations

T lymphocyte T cell-B cell-activating molecule/CD40-L molecules induce normal B cells or chronic lymphocytic leukemia B cells to express CD80 (B7/BB-1) and enhance their costimulatory activity.

1994 • 149 citations

Admixture of a recombinant vaccinia virus containing the gene for the costimulatory molecule B7 and a recombinant vaccinia virus containing a tumor-associated antigen gene results in enhanced specific T-cell responses and antitumor immunity.

1995 • 93 citations

Activation of CD4⁺ T cells by delivery of the B7 costimulatory signal on bystander antigen‐presenting cells (trans‐costimulation)

1994 • 86 citations

Characteristics of an infinite life span diploid human fibroblast cell strain and a near-diploid strain arising from a clone of cells expressing a transfectedv-myc oncogene

1991 • 85 citations

Induction of costimulatory molecule B7 in M12 B lymphomas by cAMP or MHC-restricted T cell interaction.

1993 • 65 citations

Lipopolysaccharide Effectively Up‐Regulates B7‐1 (CD80) Expression and Costimulatory Function of Human Monocytes

1995 • 51 citations

Induction of costimulatory molecules B7-1 and B7-2 in murine B cells: The CBAN mouse reveals a role for Bruton's tyrosine kinase in CD40-mediated B7 induction

1996 • 35 citations

Comparative analysis of the structure and function of the chicken c-myc and v-myc genes: v-myc is a more potent inducer of cell proliferation and apoptosis than c-myc.

1996 • 20 citations

DNA binding by the Myc oncoproteins

1993 • 13 citations

Isolation and promoter mapping of the gene encoding murine co-stimulatory factor B7-1

1996 • 12 citations

Dissociation of nuclear events on p21 RAS transformation of FDC-P1 myeloid cells: c-jun/AP-1 expression versus c-myc transcription

1992 • 11 citations

Tumorigenesis of a v-Ha-ras-expressing pre-B cell line selects for c-myc activation

1991 • 2 citations

[Studies on transforming functions of Epstein-Barr virus-specific proteins].

1990 • 2 citations