Increased Carotid Wall Elastic Modulus and Fibronectin in Aldosterone-Salt–Treated Rats

Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.

1991 • 2,017 citations

Remodeling of the rat right and left ventricles in experimental hypertension.

1990 • 676 citations

Anti-Aldosterone Treatment and the Prevention of Myocardial Fibrosis in Primary and Secondary Hyperaldosteronism

1993 • 432 citations

Vascular aldosterone. Biosynthesis and a link to angiotensin II-induced hypertrophy of vascular smooth muscle cells.

1994 • 314 citations

Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor.

1992 • 305 citations

Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension

1993 • 275 citations

Reactive and reparative myocardial fibrosis in arterial hypertension in the rat

1992 • 268 citations

Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion

1997 • 228 citations

Aldosterone Induces Angiotensin-Converting-Enzyme Gene Expression in Cultured Neonatal Rat Cardiocytes

2001 • 219 citations

Systolic blood pressure, pulse pressure and arterial stiffness as cardiovascular risk factors

2001 • 215 citations

Inverse relationship between aldosterone and large artery compliance in chronically treated heart failure patients

1998 • 200 citations

Prevention of Aortic Fibrosis by Spironolactone in Spontaneously Hypertensive Rats

1997 • 187 citations

Increased cardiac types I and III collagen mRNAs in aldosterone-salt hypertension.

1994 • 179 citations

Genetic Determination of Plasma Aldosterone Levels in Essential Hypertension

1998 • 176 citations

Biological Determinants of Aldosterone-Induced Cardiac Fibrosis in Rats

1995 • 173 citations

Fibronectin Expression and Aortic Wall Elastic Modulus in Spontaneously Hypertensive Rats

1998 • 159 citations

Association Between Increased Plasma Levels of Aldosterone and Decreased Systemic Arterial Compliance in Subjects With Essential Hypertension

1997 • 152 citations

Fibrosis, Matrix Metalloproteinases, and Inflammation in the Heart of DOCA-Salt Hypertensive Rats: Role of ET _A Receptors

2002 • 148 citations

Prevention of aortic and cardiac fibrosis by spironolactone in old normotensive rats

2001 • 145 citations

Eplerenone Suppresses Constrictive Remodeling and Collagen Accumulation After Angioplasty in Porcine Coronary Arteries

2001 • 144 citations

ET _A Receptor Antagonist Prevents Blood Pressure Elevation and Vascular Remodeling in Aldosterone-Infused Rats

2001 • 121 citations

Angiotensin-converting enzyme and myocardial fibrosis in the rat receiving angiotensin II or aldosterone.

1993 • 120 citations

Pressure and Angiotensin II Synergistically Induce Aortic Fibronectin Expression in Organ Culture Model of Rabbit Aorta

1996 • 115 citations

Effect of hypertension on fibronectin expression in the rat aorta.

1990 • 93 citations

Aldosterone infusion into the rat and dose-dependent changes in blood pressure and arterial ionic transport.

1982 • 89 citations

Aldosterone and the hypertensive kidney: its emerging role as a mediator of progressive renal dysfunction: a paradigm shift

2001 • 89 citations

Aldosterone Receptor Antagonism Normalizes Vascular Function in Liquorice-Induced Hypertension

2001 • 83 citations

Fenestrations of the Carotid Internal Elastic Lamina and Structural Adaptation in Stroke-Prone Spontaneously Hypertensive Rats

2001 • 77 citations

Effects of Valsartan on Mechanical Properties of the Carotid Artery in Spontaneously Hypertensive Rats Under High-Salt Diet

2001 • 59 citations

New Perspectives On The Role Of Aldosterone Excess In Cardiovascular Disease

2001 • 58 citations

Expression of Soluble and Insoluble Fibronectin in Rat Aorta: Effects of Angiotensin II and Endothelin-1

1993 • 40 citations

Fibronectin biosynthesis in the rat aorta in vitro. Changes due to experimental hypertension.

1991 • 38 citations

Prevention of arterial structural alterations with verapamil and trandolapril and consequences for mechanical properties in spontaneously hypertensive rats

1998 • 31 citations

Renin–angiotensin system and fibronectin gene expression in Dahl Iwai salt-sensitive and salt-resistant rats

1999 • 30 citations

Aldosterone-binding globulin-induced hypertension in the rat. A new experimental model.

1983 • 2 citations