Rate Limitations in Posttranslational Processing by the Mammary Gland of Transgenic Animalsa
Data up to Jan 2025
Total Citations Per Year
Abstract
References (20)
The Regulation of Natural Anticoagulant Pathways
1987 • 702 citations
The nucleotide sequence of the gene for human protein C.
1985 • 360 citations
Glycosylation at specific sites of erythropoietin is essential for biosynthesis, secretion, and biological function.
1988 • 232 citations
Expression, purification, and characterization of recombinant gamma-carboxylated factor IX synthesized in Chinese hamster ovary cells.
1986 • 228 citations
Expression of Human Anti-Hemophilic Factor IX in the Milk of Transgenic Sheep
1989 • 168 citations
High-level expression of a heterologous protein in the milk of transgenic swine using the cDNA encoding human protein C.
1992 • 163 citations
High-level synthesis of a heterologous milk protein in the mammary glands of transgenic swine.
1991 • 147 citations
Characterization and Novel Purification of Recombinant Human Protein C from Three Mammalian Cell Lines
1990 • 146 citations
Beta protein C is not glycosylated at asparagine 329. The rate of translation may influence the frequency of usage at asparagine-X-cysteine sites.
1990 • 141 citations
Transgenic Expression of a Variant of Human Tissue-Type Plasminogen Activator in Goat Milk: Purification and Characterization of the Recombinant Enzyme
1991 • 103 citations
Identification and purification to near homogeneity of the vitamin K-dependent carboxylase.
1991 • 96 citations
Pharmaceuticals from transgenic livestock
1987 • 86 citations
Trans–Activated Expression of Fully Gamma–Carboxylated Recombinant Human Protein C, an Antithrombotic Factor
1987 • 58 citations
Production of Biologically Active Human Protein C in the Milk of Transgenic Micea
1992 • 52 citations
Conformational changes in an epitope localized to the NH2-terminal region of protein C
1989 • 45 citations
Inefficient processing of human protein C in the mouse mammary gland
1994 • 45 citations
Amplification of multicistronic plasmids in the human 293 cell line and secretion of correctly processed recombinant human protein C
1989 • 28 citations
Post-translational Modifi cations of Proteins
2008 • 27 citations
The Porcine Mammary Gland as a Bioreactor for Complex Proteinsa
1994 • 27 citations
Viral transformation increases vitamin K-dependent γ-carboxylation of glutamate
1991 • 5 citations