Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse.

Amino Acid Difference Formula to Help Explain Protein Evolution

1974 • 2,255 citations

Sequence-specific recognition of double helical nucleic acids by proteins.

1976 • 1,123 citations

Autoantibodies to Nuclear Antigens (ANA): Their Immunobiology and Medicine

1982 • 975 citations

Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus.

1966 • 825 citations

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.

1982 • 755 citations

The role of clonal selection and somatic mutation in autoimmunity

1987 • 714 citations

Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids.

1981 • 544 citations

Profiles of Antinuclear Antibodies in Systemic Rheumatic Diseases

1975 • 365 citations

Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity.

1984 • 344 citations

Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

1981 • 319 citations

Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin.

1985 • 319 citations

Origins of anti-DNA autoantibodies.

1985 • 289 citations

Idiotypic cross-reactions of monoclonal human lupus autoantibodies.

1983 • 285 citations

Clusters of point mutations are found exclusively around rearranged antibody variable genes.

1983 • 233 citations

Antigen-binding diversity and idiotypic cross-reactions among hybridoma autoantibodies to DNA.

1981 • 171 citations

Induction of murine autoimmune disease by chronic polyclonal B cell activation.

1983 • 171 citations

Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice.

1980 • 166 citations

Antibodies to Native and Denatured Deoxyribonucleic Acid in Systemic Lupus Erythematosus*

1967 • 159 citations

Anti-DNA autoantibodies in (NZB X NZW)F1 mice are clonally heterogeneous, but the majority share a common idiotype.

1982 • 143 citations

A high frequency idiotypic marker of anti-DNA autoantibodies in MRL-Ipr/Ipr mice.

1982 • 139 citations

Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells.

1986 • 139 citations

Use of monoclonal antibodies to identify shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosus.

1983 • 127 citations

Murine monoclonal anti-DNA autoantibodies bind to endogenous bacteria.

1985 • 122 citations

Pathogenesis of immune complex glomerulonephritis of New Zealand mice.

1971 • 109 citations

Antibodies to DNA. A perspective

1986 • 97 citations

Correlation between clinical activity of systemic lupus erythematosus and the amounts of DNA in DNA/anti-DNA antibody immune complexes.

1982 • 85 citations

Genetic studies of autoimmunity in New Zealand mice. III. Associations among anti-DNA antibodies, NTA, and renal disease in (NZB x NZW)F1 x NZW backcross mice.

1981 • 71 citations

Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin.

1986 • 69 citations

A simple enzyme-linked immunosorbent assay for antibodies to native DNA

1981 • 57 citations

Role of the Sm antigen in the generation of anti-Sm autoantibodies in the SLE-prone MRL mouse.

1986 • 48 citations

Further evidence against random polyclonal antibody formation in mice with lupus-like graft-vs-host disease.

1984 • 48 citations

Detection of anti-dsDNA as diagnostic tool.

1981 • 45 citations

IgG antinuclear antibodies with cross-reactive rheumatoid factor activity.

1986 • 22 citations

Specificity analysis of monoclonal anti‐DNA antibodies from B6‐1Pr/1Pr mice

1984 • 19 citations