Methylation of coding region alone inhibits gene expression in plant protoplasts.

GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants.

1987 • 9,696 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

RNA-directed de novo methylation of genomic sequences in plants

1994 • 929 citations

Duplication of CaMV 35 S Promoter Sequences Creates a Strong Enhancer for Plant Genes

1987 • 887 citations

The Cauliflower Mosaic Virus 35 S Promoter: Combinatorial Regulation of Transcription in Plants

1990 • 644 citations

How and Why Do Plants Inactivate Homologous (Trans)genes?

1995 • 518 citations

Two tobacco DNA-binding proteins with homology to the nuclear factor CREB

1989 • 462 citations

Site-specific mutations alter in vitro factor binding and change promoter expression pattern in transgenic plants.

1989 • 411 citations

The 5'-leader sequence of tobacco mosaic virus RNA enhances the expression of foreign gene transcriptsin vitroandin vivo

1987 • 409 citations

The effect of T-DNA copy number, position and methylation on reporter gene expression in tobacco transformants

1990 • 373 citations

Multiple cis regulatory elements for maximal expression of the cauliflower mosaic virus 35S promoter in transgenic plants.

1989 • 305 citations

Dependence of transcriptional repression on CpG methylation density.

1994 • 294 citations

Epigenetic changes in the expression of the maize A1 gene inPetunia hybrida: Role of numbers of integrated gene copies and state of methylation

1990 • 289 citations

Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation.

1994 • 284 citations

Endogenous and environmental factors influence 35S promoter methylation of a maize A1 gene construct in transgenic petunia and its colour phenotype

1992 • 271 citations

Cosuppression, Flower Color Patterns, and Metastable Gene Expression States

1995 • 243 citations

Transcriptional elongation by RNA polymerase II is stimulated by transactivators

1994 • 243 citations

Homology-dependent gene silencing in transgenic plants: epistatic silencing loci contain multiple copies of methylated transgenes

1994 • 233 citations

Effect of regional DNA methylation on gene expression.

1985 • 232 citations

Cloning, characterization, and expression inEscherichia coliof the gene coding for the CpG DNA methylase fromSpiroplasma sp.strain MQ1(M Sssl)

1990 • 214 citations

DNA methylation: Molecular biology and biological significance

1993 • 193 citations

Molecular Biology of DNA Methylation

1985 • 186 citations

The methylation patterns of chromosomal integration regions influence gene activity of transferred DNA in Petunia hybrida

1992 • 161 citations

A CACGTG motif of the Antirrhinum majus chalcone synthase promoter is recognized by an evolutionarily conserved nuclear protein.

1989 • 157 citations

Gene inactivation triggered by recognition between DNA repeats

1994 • 144 citations

Differential inactivation and methylation of a transgene in plants by two suppressor loci containing homologous sequences

1991 • 138 citations

Inactive chromatin spreads from a focus of methylation.

1993 • 124 citations

CpG methylation inhibits binding of several sequence-specific DNA-binding proteins from pea, wheat, soybean and cauliflower

1991 • 124 citations

DNA methylation in eukaryotes

1995 • 121 citations

Epigenetic variants of a transgenic petunia line show hypermethylation in transgene DNA: an indication for specific recognition of foreign DNA in transgenic plants

1994 • 121 citations

Methylation induced premeiotically in Ascobolus: coextension with DNA repeat lengths and effect on transcript elongation.

1993 • 120 citations

Dependence of Transcriptional Repression on CpG Methylation Density

1994 • 112 citations

Regulation of transcriptional elongation by RNA polymerase II

1995 • 111 citations

Translation of a polycistronic mRNA in the presence of the cauliflower mosaic virus transactivator protein.

1991 • 95 citations

Proximity to the promoter inhibits recognition of cauliflower mosaic virus polyadenylation signal

1990 • 94 citations

Positive and negative control of translation by the leader sequence of cauliflower mosaic virus pregenomic 35S RNA.

1990 • 91 citations

News on initiation and elongation of transcription by RNA polymerase II

1995 • 88 citations

A plant DNA-binding protein increases the number of active preinitiation complexes in a human in vitro transcription system.

1990 • 78 citations

In vitro DNA methylation inhibits gene expression in transgenic tobacco.

1990 • 73 citations

Does the ocs‐element occur as a functional component of the promoters of plant genes?

1993 • 69 citations

Methylation in the preinitiation domain suppresses gene transcription by an indirect mechanism.

1992 • 63 citations

DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifs.

1991 • 62 citations

Eukaryotic DNA methyltransferases – structure and function

1995 • 62 citations

Petunia plants escape from negative selection against a transgene by silencing the foreign DNA via methylation

1992 • 57 citations

Distinct CG and CNG DNA methyltransferases in Pisum sativum

1995 • 57 citations

Estradiol down regulates the binding activity of an avian vitellogenin gene repressor (MDBP-2) and triggers a gradual demethylation of the mCpG pair of its DNA binding site

1991 • 54 citations

Differential inhibition of downstream gene expression by the cauliflower mosaic virus 35S RNA leader

1989 • 52 citations

Abortive Infection and Malignant Transformation by Adenoviruses: Integration of Viral Dna and Control of Viral Gene Expression by Specific Patterns of DNA Methylation

1991 • 50 citations

MIP: An Epigenetic Gene Silencing Process in Ascobolus immersus

1995 • 45 citations

Methylation of single sites within the herpes simplex virus tk coding region and the simian virus 40 T-antigen intron causes gene inactivation.

1994 • 39 citations

Inactive Chromatin Spreads from a Focus of Methylation

1993 • 37 citations

Gene Silencing in Transgenic Plants: A Heuristic Autoregulation Model

1995 • 37 citations

Extrachromosomal homologous DNA recombination in plant cells is fast and is not affected by CpG methylation.

1992 • 33 citations

Effect of CpG methylation on gene expression in transfected plant protoplasts

1990 • 27 citations

Methylation of Single Sites within the Herpes Simplex Virus tk Coding Region and the Simian Virus 40 T-Antigen Intron Causes Gene Inactivation

1994 • 5 citations