Epstein-Barr virus infection is associated with p53 accumulation in nasopharyngeal carcinoma

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1992 • 3,110 citations

The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation

1986 • 927 citations

Association of p53 Protein Expression With Tumor Cell Proliferation Rate and Clinical Outcome in Node-Negative Breast Cancer

1993 • 777 citations

Clonal Proliferations of Cells Infected with Epstein–Barr Virus in Preinvasive Lesions Related to Nasopharyngeal Carcinoma

1995 • 599 citations

An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms

1994 • 513 citations

EBNA-5, an Epstein-Barr virus-encoded nuclear antigen, binds to the retinoblastoma and p53 proteins.

1993 • 312 citations

Functional and physical interaction between p53 and BZLF1: implications for Epstein-Barr virus latency.

1994 • 242 citations

Epstein–Barr virus infection and replication in a human epithelial cell system

1992 • 225 citations

Role of the human papillomaviruses in human cancer.

1991 • 212 citations

The Epstein-Barr virus bZIP transcription factor Zta causes G0/G1 cell cycle arrest through induction of cyclin-dependent kinase inhibitors.

1996 • 182 citations

Histological typing of upper respiratory tract tumours

1978 • 171 citations

Nasopharyngeal carcinoma: the Epstein-Barr virus association.

1994 • 164 citations

Epstein-barr virus infection is an early event in gastric carcinogenesis and is independent of bcl-2 expression and p53 accumulation

1996 • 159 citations

Epstein-Barr virus DNA is abundant and monoclonal in the Reed-Sternberg cells of Hodgkin's disease: association with mixed cellularity subtype and Hispanic American ethnicity

1994 • 147 citations

Alterations of the p53 gene in nasopharyngeal carcinoma

1992 • 137 citations

The bZIP transactivator of Epstein-Barr virus, BZLF1, functionally and physically interacts with the p65 subunit of NF-kappa B.

1994 • 129 citations

Epstein-barr virus is detected in undifferentiated nasopharyngeal carcinoma but not in lymphoepitheliomalike carcinoma of the urinary bladder

1995 • 123 citations

Absence of p53 gene mutations in primary nasopharyngeal carcinomas.

1992 • 121 citations

Histology of the human nasopharyngeal mucosa.

1965 • 117 citations

Analysis of epstein‐barr virus infection in nasopharyngeal biopsies from a group at high risk of nasopharyngeal carcinoma

1993 • 107 citations

Qualitative analysis of the expression of Epstein--Barr virus lytic genes in nasopharyngeal carcinoma biopsies

1995 • 105 citations

Dissection of the genetic programs of p53-mediated G1 growth arrest and apoptosis: blocking p53-induced apoptosis unmasks G1 arrest

1995 • 100 citations

P53 overexpression and Epstein‐Barr virus infection in undifferentiated and squamous cell nasopharyngeal carcinomas

1993 • 94 citations

Epstein-Barr-encoded RNA in situ hybridization: Diagnostic applications

1994 • 85 citations

Differences in the growth pattern and clinical course of EBV-LMP1 expressing and non-expressing nasopharyngeal carcinomas

1995 • 83 citations

Epstein‐barr virus carriage by nasopharyngeal carcinoma in situ

1993 • 81 citations

Assessment of p53 expression in nasopharyngeal carcinoma*1

1995 • 77 citations

Epstein-Barr virus nuclear antigen 2 and latent membrane protein independently transactivate p53 through induction of NF-kappaB activity

1996 • 62 citations

p53 is overexpressed in fifty percent of pre-invasive lesions of head and neck epithelium

1994 • 59 citations

A possible prognostic role of immunoglobulin-G antibody against recombinant Epstein-Barr virus BZLF-1 transactivator protein ZEBRA in patients with nasopharyngeal carcinoma

1994 • 58 citations

p53 mutation in human nasopharyngeal carcinomas.

1992 • 48 citations

Detection of the tumour suppressor gene p53 in nasopharyngeal carcinoma in Hong Kong Chinese.

1994 • 31 citations

Detection of mutations in the p53 gene in human head and neck carinomas by single strand conformation polymorphism analysis

1992 • 28 citations

A molecular study of EBV DNA and p53 mutations in nasopharyngeal carcinoma of Saudi Arab patients

1994 • 23 citations

Mutations clustered in exon 5 of the p⁵³ gene in primary nasopharyngeal carcinomas from Southeastern Asia

1995 • 22 citations

The Clonal Progression in the Neoplastic Process of Nasopharyngeal Carcinoma

1996 • 20 citations

Expression of bcl-2 and p53 proteins in nasopharyngeal carcinoma. Absence of correlation with the presence of EBV encoded EBER1-2 transcripts and latent membrane protein-1

1995 • 18 citations

Cytodiagnosis of nasopharyngeal carcinoma.

1967 • 17 citations

Nasopharyngeal carcinoma in situ in nasopharyngeal carcinoma.

1992 • 11 citations

In-situ Carcinoma Adjacent to Recurrent Nasopharyngeal Carcinoma

1993 • 6 citations