SMN, the Product of the Spinal Muscular Atrophy Gene, Binds Preferentially to Dimethylarginine-Containing Protein Targets

Identification and characterization of a spinal muscular atrophy-determining gene

1995 • 3,722 citations

Multiple Sclerosis

2000 • 2,813 citations

Regulation of Transcription by a Protein Methyltransferase

1999 • 1,169 citations

A novel nuclear structure containing the survival of motor neurons protein.

1996 • 759 citations

The SMN–SIP1 Complex Has an Essential Role in Spliceosomal snRNP Biogenesis

1997 • 650 citations

The Spinal Muscular Atrophy Disease Gene Product, SMN, and Its Associated Protein SIP1 Are in a Complex with Spliceosomal snRNP Proteins

1997 • 636 citations

A Novel Function for SMN, the Spinal Muscular Atrophy Disease Gene Product, in Pre-mRNA Splicing

1998 • 545 citations

RNA and Protein Interactions Modulated by Protein Arginine Methylation

1998 • 499 citations

SMN oligomerization defect correlates with spinal muscular atrophy severity

1998 • 493 citations

Myelin in multiple sclerosis is developmentally immature.

1994 • 316 citations

In Vivo and In Vitro Arginine Methylation of RNA-Binding Proteins

1995 • 302 citations

Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs.

1995 • 294 citations

Arginine methylation facilitates the nuclear export of hnRNP proteins

1998 • 287 citations

Folate and vitamin B₁₂

1999 • 287 citations

The C-terminal RG Dipeptide Repeats of the Spliceosomal Sm Proteins D1 and D3 Contain Symmetrical Dimethylarginines, Which Form a Major B-cell Epitope for Anti-Sm Autoantibodies

2000 • 285 citations

When Is a Deletion Not a Deletion? When It Is Converted

1997 • 270 citations

Gemin3

1999 • 263 citations

Transportin-mediated Nuclear Import of Heterogeneous Nuclear RNP Proteins

1997 • 252 citations

Essential Role for the Tudor Domain of SMN in Spliceosomal U snRNP Assembly: Implications for Spinal Muscular Atrophy

1999 • 250 citations

snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions.

1995 • 248 citations

SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins

1999 • 243 citations

Arginine Methylation Inhibits the Binding of Proline-rich Ligands to Src Homology 3, but Not WW, Domains

2000 • 240 citations

Gemin4

2000 • 234 citations

A Functional Interaction between the Survival Motor Neuron Complex and RNA Polymerase II

2001 • 223 citations

Protein Methylase I

1968 • 212 citations

Specific Enzymic Methylation of an Arginine in the Experimental Allergic Encephalomyelitis Protein from Human Myelin

1971 • 197 citations

A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor

1997 • 179 citations

A Novel Methyltransferase (Hmt1p) Modifies Poly(A)⁺-RNA-Binding Proteins

1996 • 161 citations

Enzymatic methylation of protein fractions from calf thymus nuclei

1967 • 158 citations

Specific Sequences of the Sm and Sm-like (Lsm) Proteins Mediate Their Interaction with the Spinal Muscular Atrophy Disease Gene Product (SMN)

2000 • 134 citations

Spinal muscular atrophy

1997 • 87 citations

A hungarian study on Werdnig-Hoffmann disease.

1989 • 78 citations

Candidate autoantigens in multiple sclerosis

1999 • 77 citations

Deimination of Myelin Basic Protein. 2. Effect of Methylation of MBP on Its Deimination by Peptidylarginine Deiminase

2000 • 77 citations

The nucleolar protein, B-36, contains a glycine and dimethylarginine-rich sequence conserved in several other nuclear RNA-binding proteins

1988 • 53 citations

Diversity of methyl acceptor proteins in rat pheochromocytoma (PC12) cells revealed after treatment with adenosine dialdehyde.

1990 • 45 citations

Functions of U-snRNPs

1990 • 35 citations

ProteinN-Arginine Methylation in Adenosine Dialdehyde-Treated Lymphoblastoid Cells

1998 • 26 citations

Biochemical Analysis of Myelin Lipids and Proteins in a Model of Methyl Donor Pathway Deficit: Effect of S-Adenosylmethionine

1999 • 14 citations