Nucleotide and pentose synthesis after serum‐stimulation of resting 3T6 fibroblasts

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The initiation of cell division in a contact‐inhibited mammalian cell line

1965 • 807 citations

Adenylate Energy Charge inEscherichia coliDuring Growth and Starvation

1971 • 772 citations

Transport of Amino Acids by Confluent and Nonconfluent 3T3 and Polyoma Virus-transformed 3T3 Cells Growing on Glass Cover Slips

1969 • 335 citations

Levels of oxidized and reduced diphosphopyridine nucleotide and triphosphopyridine nucleotide in animal tissues

1955 • 291 citations

TRANSPORT CHANGES RAPIDLY INITIATED BY SERUM ADDITION TO “CONTACT INHIBITED” 3T3 CELLS

1969 • 285 citations

A Unifying Hypothesis Concerning the Nature of Malignant Growth

1972 • 282 citations

Biochemical Bases of Accelerated Purine Biosynthesis de Novo in Human Fibroblasts Lacking Hypoxanthine-Guanine Phosphoribosyltransferase

1968 • 251 citations

The performance of microparticle chemically-bonded anion-exchange resins in the analysis of nucleotides

1975 • 220 citations

Regulation of the synthesis of 5-phosphoribosyl-i-pyrophosphate in intact red blood cells and in cell-free preparations

1969 • 204 citations

Human Phosphoribosylpyrophosphate Synthetase

1971 • 202 citations

CARBOHYDRATE METABOLISM IN ASCITES TUMOR CELLS

1956 • 185 citations

Stimulation of Glucose Transport in Cultures of Density-Inhibited Chick Embryo Cells

1971 • 177 citations

Human Phosphoribosylpyrophosphate Synthetase

1972 • 163 citations

Synthesis of 5-Phosphoribosyl 1-Pyrophosphate from Glucose in Ehrlich Ascites Tumor Cells in Vitro

1965 • 157 citations

Feedback Inhibition of Purine Biosynthesis in Ascites Tumor Cells

1962 • 154 citations

pH AND POPULATION DENSITY IN THE REGULATION OF ANIMAL CELL MULTIPLICATION

1971 • 136 citations

Glycolysis in quiescent cultures of 3T3 cells. Stimulation by serum, epidermal growth factor, and insulin in intact cells and persistence of the stimulation after cell homogenization.

1978 • 128 citations

Phosphate Transport, Nucleotide Pools, and Ribonucleic Acid Synthesis in Growing and in Density-inhibited 3T3 Cells

1971 • 122 citations

Regulation of RNA Synthesis in Fibroblasts During Transition from Resting to Growing State

1973 • 120 citations

Adenosine Triphosphate Conservation in Biosynthetic Regulation

1967 • 115 citations

The Effect of Growth Conditions on NAD+ and NADH Concentrations and the NAD+:NADH Ratio in Normal and Transformed Fibroblasts

1974 • 115 citations

Glycolysis of quiescent cultures of 3T3 cells. Addition of serum, epidermal growth factor, and insulin increases the activity of phosphofructokinase in a protein synthesis-independent manner.

1978 • 97 citations

Kinetics of Early Changes in Phosphate and Uridine Transport and Cyclic AMP Levels Stimulated by Serum in Density-Inhibited 3T3 Cells

1974 • 92 citations

Nucleotide pool levels in growing, inhibited, and transformed chick fibroblast cells

1970 • 91 citations

Repression and Derepression of Purine Biosynthesis in Mammalian Hepatoma Cells in Culture

1972 • 83 citations

Multiple control mechanisms underlie initiation of growth in animal cells

1974 • 82 citations

Cyclic Nucleotides and Growth Control in Cultured Mouse Cells: Correlation of Changes in Intracellular 3′:5′cGMP Concentration with a Specific Phase of the Cell Cycle

1974 • 80 citations

Activation of Phosphofructokinase by Stimulants of Cell Multiplication

1973 • 72 citations

The effect of cyclic nucleotides on purine biosynthesis and the induction of PRPP synthetase during lymphocyte activation

1974 • 67 citations

Human erythrocyte phosphoribosylpyrophosphate synthetase. Dependence of activity on state of subunit association.

1977 • 65 citations

Uptake of nucleosides in density-inhibited cultures of 3T3 cells

1977 • 62 citations

Human erythrocyte phosphoribosylpyrophosphate synthetase. Subunit analysis and states of subunit association.

1977 • 58 citations

Interrelationship and control of glucose metabolism and lipogenesis in isolated fat-cells. Control of pentose phosphate-cycle activity by cellular requirement for reduced nicotinamide adenine dinucleotide phosphate

1972 • 54 citations

Activation by 5-phosphoribosyl 1-pyrophosphate of glutamine-dependent carbamyl phosphate synthetase from mouse spleen

1972 • 54 citations

Growth control in chick embryo fibroblasts; no evidence for a specific role for cyclic purine nucleotides

1974 • 51 citations

Dynamics of Metabolism of Normal and Virus-Transformed Chick Cells in Culture

1973 • 45 citations

A direct, stimulating effect of cyclic GMP on purified phosphoribosyl pyrophosphate synthetase and its antagonism by cyclic AMP

1974 • 39 citations

Serum‐stimulated phosphate uptake and initiation of fibroblast proliferation

1977 • 34 citations

Serum stimulation of Phosphate uptake into 3T3 cells

1976 • 33 citations

Kinetics of amidophosphoribosyltransferase in intact tumor cells

1974 • 26 citations

Hexose uptake and control of fibroblast proliferation

1977 • 25 citations

Increased PRPP synthetase activity in cultured rat hepatoma cells containing mutations in the hypoxanthine‐guanine phosphoribosyltransferase gene

1976 • 25 citations

The effect of serum on the transport and phosphorylation of 2‐deoxyglucose by untransformed and transformed mouse 3T3 cells

1975 • 21 citations

Absence of demonstrable linkage of human genes for enzymes of the purine and pyrimidine salvage pathways in human-mouse somatic cell hybrids

1973 • 20 citations

Pyrolysis of municipal solid waste

1974 • 16 citations

Increasing content of poly A(+) mRNA of serum‐stimulated cells in the absence of ribosome synthesis

1976 • 15 citations

Stimulation by serum of the phosphorylation reactions in density-inhibited 3T3 cells

1976 • 12 citations

Adrenocorticotropin-induced generation of 5′-phosphoribosylpyrophosphate and its relation to nucleotide synthesis in the adrenal cortex

1969 • 9 citations

Effects of Actinomycin D on Purine Ribonucleotide Metabolism in Ehrlich Ascites Tumor Cells In Vitro

1974 • 8 citations