Kinetics of amidophosphoribosyltransferase in intact tumor cells

CONCENTRATIVE UPTAKE OF AMINO ACIDS BY THE EHRLICH MOUSE ASCITES CARCINOMA CELL

1952 • 224 citations

The rapid separation of nucleotides in cell extracts using high-pressure liquid chromatography

1970 • 217 citations

Enzyme Concentrations in Tissues

1967 • 215 citations

Human Glutamine Phosphoribosylpyrophosphate Amidotransferase

1973 • 175 citations

Rate-limiting steps in the interconversion of purine ribonucleotides in Ehrlich ascites tumor cells in vitro.

1971 • 173 citations

Assay of Yeast Enzymes in situ

1973 • 163 citations

Synthesis of 5-Phosphoribosyl 1-Pyrophosphate from Glucose in Ehrlich Ascites Tumor Cells in Vitro

1965 • 157 citations

Feedback Inhibition of Purine Biosynthesis in Ascites Tumor Cells

1962 • 154 citations

Purification and properties of 5-phosphoribosylpyrophosphate amidotransferase from adenocarcinoma 755 cells

1969 • 131 citations

Quantitative extraction and estimation of intracellular nucleoside triphosphates of Escherichia coli

1972 • 130 citations

Regulation of Escherichia coli phosphofructokinase in situ

1973 • 119 citations

Alternative Pathways of Deoxyadenosine and Adenosine Metabolism

1973 • 99 citations

On the Mechanism of Feedback Inhibition of Purine Biosynthesis de Novo in Ehrlich Ascites Tumor Cells in Vitro

1965 • 93 citations

Inhibition of phosphoribosyl pyrophosphate amidotransferase from Ehrlich ascites-tumour cells by thiopurine nucleotides

1969 • 90 citations

Regulation of purine biosynthesis in cultured human cells

1970 • 87 citations

Activity and Mechanism of Action of 6-Methylthiopurine Ribonucleoside in Cancer Cells Resistant to 6-Mercaptopurine

1965 • 83 citations

Properties of 5-Phosphoribosyl-1-pyrophosphate Amidotransferase from Human Lymphoblasts

1973 • 81 citations

Availability of 5-Phosphoribosyl 1-Pyrophosphate for Ribonucleotide Synthesis in Ehrlich Ascites Tumor Cells in Vitro

1965 • 67 citations

Kinetic Studies of Adenosine Kinase from Ehrlich Ascites Tumor Cells

1972 • 61 citations

The Enzymatic Synthesis of 5-Fluorouridine 5′-Phosphate

1959 • 55 citations

THE ENZYMIC FORMATION OF 6-(METHYLMERCAPTO)PURINE RIBONUCLEOSIDE 5′-PHOSPHATE

1966 • 54 citations

Purine Biosynthesis de Novo in Mouse Tissues and a Mouse Tumor

1959 • 51 citations

In situ regulation of yeast citrate synthase. Absence of ATP inhibition observed in vitro

1973 • 49 citations

RESISTANCE TO PURINE RIBONUCLEOSIDE ANALOGUES IN AN ASCITES TUMOR

1967 • 46 citations

Behaviour of enzymes at high concentration, use of permeabilised cells in the study of enzyme activity and its regulation

1973 • 45 citations

Feedback inhibition of purine biosynthesis in ascites tumor cells by purine analogues

1963 • 43 citations

Biochemical effects of formycin, an adenosine analog.

1967 • 39 citations

Radioassay for enzymic production of glutamate from glutamine

1972 • 38 citations

AN ANALYSIS OF THE LACK OF DRUG SYNERGISM DURING SEQUENTIAL BLOCKADE OF DE NOVO PYRIMIDINE BIOSYNTHESIS.

1964 • 33 citations

The effect of glucose on glutamine utilization by Ehrlich ascites tumor cells.

1961 • 30 citations

Sources of nitrogen as rate-limiting factors for purine biosynthesis de novo in Ehrlich ascites tumor cells

1969 • 27 citations

Control in situ of the pyruvate kinase activity of Escherichia coli

1973 • 25 citations

Effect of glutamine analogs on amino acid incorporation into protein of some normal and neoplastic cells in vitro.

1959 • 19 citations

Inhibition of purine biosynthesis de novo and of Ehrlich ascites tumor cell growth by 6-methylmercaptopurine ribonucleoside

1972 • 9 citations