Activation of a pro‐apoptotic amplification loop through inhibition of NF‐κB‐dependent survival signals by caspase‐mediated inactivation of RIP

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

1998 • 4,383 citations

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

1998 • 3,603 citations

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

1998 • 2,698 citations

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1998 • 1,651 citations

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1997 • 1,305 citations

The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

1998 • 1,062 citations

Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis

1999 • 804 citations

MyD88, an Adapter Protein Involved in Interleukin-1 Signaling

1998 • 634 citations

RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis.

1996 • 540 citations

Proteolytic Activation of Protein Kinase C δ by an ICE/CED 3-like Protease Induces Characteristics of Apoptosis

1996 • 484 citations

Caspase-3-dependent Cleavage of Bcl-2 Promotes Release of Cytochrome c

1999 • 461 citations

Cell death induction by TNF: a matter of self control

1997 • 231 citations

Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-κB loop

1999 • 188 citations

Resistance of cultured peripheral T cells towards activation‐induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death‐inducing signaling complex

1997 • 172 citations

Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1

1998 • 122 citations

NF-κB regulates Fas / APO-1 / CD95- and TCR-mediated apoptosis of T lymphocytes

1999 • 87 citations