Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-κB loop

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

NF-κB: Ten Years After

1996 • 3,008 citations

TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

1996 • 2,665 citations

Suppression of TNF-α-Induced Apoptosis by NF-κB

1996 • 2,623 citations

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

1994 • 2,124 citations

Caspases: Intracellular Signaling by Proteolysis

1997 • 2,114 citations

Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death

1996 • 1,962 citations

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1995 • 1,849 citations

NF-κB: A lesson in family values

1995 • 1,266 citations

Phosphorylation of NF-κB p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300

1998 • 1,200 citations

Conversion of Bcl-2 to a Bax-like Death Effector by Caspases

1997 • 1,116 citations

Substrate Specificities of Caspase Family Proteases

1997 • 871 citations

CREB-binding protein/p300 are transcriptional coactivators of p65

1997 • 819 citations

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.

1997 • 780 citations

Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator

1997 • 725 citations

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer.

1997 • 717 citations

Apoptosis: Activate NF-κB or die?

1997 • 524 citations

NF-κB Activation: The IκB Kinase Revealed?

1997 • 492 citations

A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing

1988 • 485 citations

NF-κB Mediates αvβ3 Integrin-induced Endothelial Cell Survival

1998 • 484 citations

Caspases: key mediators of apoptosis

1998 • 469 citations

Cleavage of p21Cip1/Waf1 and p27Kip1 Mediates Apoptosis in Endothelial Cells through Activation of Cdk2: Role of a Caspase Cascade

1998 • 441 citations

Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis.

1996 • 352 citations

Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death.

1994 • 304 citations

Caspase-mediated Cleavage of Focal Adhesion Kinase pp125FAK and Disassembly of Focal Adhesions in Human Endothelial Cell Apoptosis

1998 • 258 citations

Endothelial Cell Death Induced by Tumor Necrosis Factor-α Is Inhibited by the Bcl-2 Family Member, A1

1996 • 247 citations

Suppression of Apoptosis by Dominant Negative Mutants of Cyclin-dependent Protein Kinases

1996 • 239 citations

Local Fas/APO‐1 (CD95) ligand‐mediated tumor cell killing in vivo

1995 • 201 citations

Structural and functional analysis of the NF-kappa B p65 C terminus. An acidic and modular transactivation domain with the potential to adopt an alpha-helical conformation.

1994 • 158 citations

Interleukin-1β and Glutamate Activate the NF-κB/Rel Binding Site from the Regulatory Region of the Amyloid Precursor Protein Gene in Primary Neuronal Cultures

1996 • 152 citations

Phosphorylation of IκB-α Inhibits Its Cleavage by Caspase CPP32 in Vitro

1997 • 147 citations

The CD95 (APO-1/Fas) Receptor Activates NF- B Independently of Its Cytotoxic Function

1996 • 146 citations

CD95 (Fas)-induced caspase-mediated proteolysis of NF-kappaB.

1998 • 123 citations

Bcl-2 Prevents CD95 (Fas/APO-1)-induced Degradation of Lamin B and Poly(ADP-ribose) Polymerase and Restores the NF-κB Signaling Pathway

1996 • 107 citations

Fibronectin attachment activates the NF-kappa B p50/p65 heterodimer in fibroblasts and smooth muscle cells.

1994 • 87 citations

Identification of a ras-Activated Enhancer in the Mouse Osteopontin Promoter and Its Interaction with a Putative ETS-Related Transcription Factor Whose Activity Correlates with the Metastatic Potential of the Cell

1995 • 84 citations