Metabolism of promutagens catalyzed byDrosophila melanogaster CYP6A2 enzyme inSaccharomyces cerevisiae

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Molecular cloning: A laboratory manual

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DNA sequencing with chain-terminating inhibitors

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

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Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

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A comprehensive set of sequence analysis programs for the VAX

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Antibodies, a laboratory manual

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The Carbon Monoxide-binding Pigment of Liver Microsomes

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A Multiple Comparison Procedure for Comparing Several Treatments with a Control

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Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

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Enzyme-linked immunosorbent assay (ELISA) quantitative assay of immunoglobulin G

1971 • 3,630 citations

[1] Getting started with yeast

1991 • 2,456 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

Molecular Biology of Mutagens and Carcinogens

1983 • 803 citations

Somatic mutation and recombination test in Drosophila melanogaster

1984 • 662 citations

A general method for polyethylene-glycol-induced genetic transformation of bacteria and yeast

1983 • 462 citations

Cloning of DNA sequences from the white locus of D. melanogaster by a novel and general method

1981 • 446 citations

[31] Tackling the protease problem in Saccharomyces cerevisiae

1991 • 427 citations

Splicing signals inDrosophila: intron size, information content, and consensus sequences

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A yeast strain for simultaneous detection of induced mitotic crossing over, mitotic gene conversion and reverse mutation

1975 • 365 citations

Human cytochromes P450: problems and prospects

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Cloning Human Fetal γ Globin and Mouse α-Type Globin DNA: Preparation and Screening of Shotgun Collections

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Genetics and Molecular Biology of Industrial Microorganisms

1989 • 319 citations

Evaluation of short-term tests for carcinogens

1986 • 280 citations

Thirty compounds tested in the Drosophila wing spot test

1989 • 219 citations

Improved high bioactivation cross for the wing somatic mutation and recombination test in Drosophila melanogaster

1992 • 215 citations

A host-inducible cytochrome P-450 from a host-specific caterpillar: molecular cloning and evolution.

1992 • 191 citations

Isolation of two developmentally regulated genes involved in spore wall maturation in Saccharomyces cerevisiae.

1990 • 190 citations

Primary Structure of the P450 Lanosterol Demethylase Gene fromSaccharomyces cerevisiae

1987 • 178 citations

Performance of 181 chemicals in a Drosophila assay predominantly monitoring interchromosomal mitotic recombination

1993 • 162 citations

Isolation and sequence of cDNA encoding a cytochrome P-450 from an insecticide-resistant strain of the house fly, Musca domestica.

1989 • 155 citations

Genetic toxicology of environmental chemicals. Part B: Genetic effects and applied mutagenesis

1986 • 146 citations

Testing of chemicals for genetic activity with Saccharomyces cerevisiae: a report of the U.S. environmental protection agency gene-tox program

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Induction, detection and characterization of cell differentiation mutants inDrosophila

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Cytochrome P450 family 4 in a cockroach: molecular cloning and regulation by regulation by hypertrehalosemic hormone.

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Induction of mitotic gene conversion with nitrous acid, 1-methyl-3-nitro-1-nitrosoguanidine and other alkylating agents in Saccharomyces cerevisiae

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Ecological Significance of Mixed-Function Oxidations

1979 • 120 citations

Heterologous Gene Expression inSaccharomyces cerevisiae

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Studies on the Microsomal Electron-transport System of Anaerobically Grown Yeast

1977 • 92 citations

Mammalian cell mutagenicity and metabolism of heterocyclic aromatic amines

1991 • 90 citations

New tester strains with improved bioactivation capacity for the Drosophila wing-spot test

1989 • 88 citations

Human NADPH-P450 oxidoreductase: complementary DNA cloning, sequence and vaccinia virus-mediated expression and localization of the CYPOR gene to chromosome 7.

1989 • 87 citations

CHROMOSOMAL ANALYSIS OF DDT-RESISTANCE IN A LONG-TERM SELECTED POPULATION OF DROSOPHILA MELANOGASTER

1977 • 87 citations

Cytochrome P-450-mediated activation of pro-carcinogens and promutagens to DNA-damaging products by measuring expression of umu gene in Salmonella typhimurium TA1535/pSK1002

1987 • 71 citations

NCI-Black-Reiter (NBR) male rats fail to develop renal disease following exposure to agents that induce ?-2u-globulin (?2u) nephropathy*1

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Chapter 6 Genetic and Variegation Mosaics in the Eye of Drosophila

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Drosophila wing-spot test: improved detectability of genotoxicity of polycyclic aromatic hydrocarbons

1990 • 57 citations

Molecular Analysis of a Cytochrome P450 Gene of Family 4 on theDrosophilaX Chromosome

1992 • 57 citations

Structure and chromosomal localization of CYP6A1, a cytochrome P450-encoding gene from the house fly

1994 • 57 citations

Genetic variation in cytochrome P-450 and xenobiotic metabolism in Drosophila melanogaster

1984 • 55 citations

Isolation and Characterization of Fifteen Ecdysone-Inducible Drosophila Genes Reveal Unexpected Complexities in Ecdysone Regulation

1993 • 55 citations

Genotoxicity of ethyl carbamate in the Drosophila wing spot test: dependence on genotype-controlled metabolic capacity

1990 • 54 citations

Constitutive and inducible expression of human cytochrome P450IA1 in yeast Saccharomyces cerevisiae: An alternative enzyme source for in vitro studies

1990 • 52 citations

Genetic regulation of the cytochrome P-450 system in Drosophila melanogaster. I. Chromosomal determination of some cytochrome P-450-dependent reactions

1985 • 52 citations

Chemical Mutagens. Principles and Methods for their Detection

1986 • 50 citations

Isolation and characterization of fifteen ecdysone-inducible Drosophila genes reveal unexpected complexities in ecdysone regulation.

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A pilot study on a new Drosophila spot test

1983 • 49 citations

Tests for recombinagens in somatic cells of Drosophila

1992 • 45 citations

High promutagen activating capacity of yeast microsomes containing human cytochrome P-450 1A and human NADPH-cytochrome P-450 reductase

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Genetic-molecular basis for a simple Drosophila melanogaster somatic system that detects environmental mutagens.

1986 • 37 citations

Cluster of Cytochrome P450 Genes on the X Chromosome ofDrosophila melanogaster

1994 • 36 citations

F1 and F2: Two similar genes regulated differently during development of Drosophila melanogaster

1985 • 34 citations

DNA recombination induced by aflatoxin B₁ activated by cytochrome P450 1A enzymes

1994 • 34 citations

Mammalian genes expressed in Drosophila: a transgenic model for the study of mechanisms of chemical mutagenesis and metabolism.

1991 • 32 citations

Functional co-expression of human oxidoreductase and cytochrome P450 1A1 in Saccharomyces cerevisiae results in increased erod activity

1992 • 29 citations

Induction of genetic recombination: Consequences and model systems

1994 • 28 citations

Heterologous expression of human microsomal epoxide hydrolase in saccharomyces cerevisiae

1991 • 22 citations

Mutagenic potency of heterocyclic amines in the Drosophila wing spot test and its correlation to carcinogenic potency.

1985 • 15 citations

Genetic regulation of the cytochrome P-450 system in Drosophila melanogaster.

1986 • 13 citations

Cytochrome P450 in Insects

1993 • 12 citations

Correction: Possible Involvement of the Long Terminal Repeat of Transposable Element 17.6 in Regulating Expression of an Insecticide Resistance-Associated P450 Gene in Drosophila

1992 • 2 citations