Protein folding in the cytosol: chaperonin-dependent and -independent mechanisms

Molecular chaperones in cellular protein folding

1996 • 3,540 citations

Protein Folding

1992 • 1,601 citations

Macromolecular Crowding: Biochemical, Biophysical, and Physiological Consequences

1993 • 1,474 citations

The crystal structure of the asymmetric GroEL–GroES–(ADP)7 chaperonin complex

1997 • 1,250 citations

Role of the Major Heat Shock Proteins as Molecular Chaperones

1993 • 1,096 citations

The purification of eukaryotic polypeptides synthesized in Escherichia coli

1986 • 838 citations

Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries

1997 • 797 citations

The groES and groEL heat shock gene products of Escherichia coli are essential for bacterial growth at all temperatures

1989 • 693 citations

A protein complex required for signal-sequence-specific sorting and translocation

1994 • 404 citations

Recombination of protein domains facilitated by co-translational folding in eukaryotes

1997 • 400 citations

Interaction of Hsp70 chaperones with substrates

1997 • 372 citations

Folding in vivo of bacterial cytoplasmic proteins: Role of GroEL

1993 • 345 citations

In Vivo Observation of Polypeptide Flux through the Bacterial Chaperonin System

1997 • 345 citations

GroEL‐Mediated protein folding

1997 • 336 citations

Chaperones get in touch: the Hip-Hop connection

1997 • 289 citations

The Chaperonin Containing t-complex polypeptide 1 (TCP-1). Multisubunit Machinery Assisting in Protein Folding and Assembly in the Eukaryotic Cytosol

1995 • 279 citations

Principles of Chaperone-Assisted Protein Folding: Differences Between in Vitro and in Vivo Mechanisms

1996 • 249 citations

Protein folding in the cell: competing models of chaperonin function

1996 • 238 citations

A quantitative assessment of the role of the chaperonin proteins in protein folding in vivo

1996 • 235 citations

The Chaperonin Containing t-complex polypeptide 1 (TCP-1). Multisubunit Machinery Assisting in Protein Folding and Assembly in the Eukaryotic Cytosol

1995 • 213 citations

Functional Specificity Among Hsp70 Molecular Chaperones

1997 • 206 citations

Role of the Host Cell in Bacteriophage Morphogenesis: Effects of a Bacterial Mutation on T4 Head Assembly

1972 • 178 citations

Protein Folding In Vivo: Unraveling Complex Pathways

1997 • 170 citations

Structure of the Substrate Binding Domain of the Thermosome, an Archaeal Group II Chaperonin

1997 • 162 citations

Chaperonin-mediated folding of actin and tubulin.

1996 • 145 citations

Substrate Shuttling Between the DnaK and GroEL Systems Indicates a Chaperone Network Promoting Protein Folding

1996 • 145 citations

The general concept of molecular chaperones

1993 • 140 citations

Complexes between nascent polypeptides and their molecular chaperones in the cytosol of mammalian cells.

1997 • 101 citations

Structural Adaptations in the Specialized Bacteriophage T4 Co-Chaperonin Gp31 Expand the Size of the Anfinsen Cage

1997 • 98 citations

Ribosomes and ribosomal RNA as chaperones for folding of proteins

1997 • 94 citations

PEDANTic genome analysis

1997 • 90 citations

Roles of molecular chaperones in protein folding

1994 • 77 citations

Drifting Through the Year

1972 • 71 citations