Protein Kinase C: Seeing two domains

Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

1992 • 4,480 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Multiple, Distinct Forms of Bovine and Human Protein Kinase C Suggest Diversity in Cellular Signaling Pathways

1986 • 1,044 citations

Localization of Protein Kinases by Anchoring Proteins: a Theme in Signal Transduction

1995 • 911 citations

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

1990 • 829 citations

Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold

1995 • 680 citations

The Photosynthetic Reaction Center from the Purple Bacterium Rhodopseudomonas viridis

1989 • 670 citations

Crystal structure of the Cys2 activator-binding domain of protein kinase Cδ in complex with phorbol ester

1995 • 643 citations

A novel phorbol ester receptor/protein kinase, nPKC, distantly related to the protein kinase C family

1988 • 414 citations

The Photosynthetic Reaction Center from the purple bacteriumRhodopseudomonas viridis

1990 • 219 citations

Identification and Characterization of Zinc Binding Sites in Protein Kinase C

1991 • 193 citations

Interaction of Proteins With Lipid Headgroups: Lessons from Protein Kinase C

1993 • 184 citations

Isolation and characterization of two new Drosophila protein kinase C genes, including one specifically expressed in photoreceptor cells

1989 • 167 citations

Intrapeptide regulation of protein kinase C.

1994 • 139 citations

Solution structure of a cysteine rich domain of rat protein kinase C

1994 • 131 citations

Phosphatidyl-L-serine Is Necessary for Protein Kinase C's High-Affinity Interaction with Diacylglycerol-Containing Membranes

1994 • 124 citations

Zinc finger domains and phorbol ester pharmacophore. Analysis of binding to mutated form of protein kinase C zeta and the vav and c-raf proto-oncogene products

1994 • 120 citations

The cysteine-rich domain of human proteins, neuronal chimaerin, protein kinase C and diacylglycerol kinase binds zinc. Evidence for the involvement of a zinc-dependent structure in phorbol ester binding

1991 • 115 citations

Structural basis of protein kinase C activation by diacylglycerols and tumor promoters

1992 • 72 citations

Ca2+-independent protein kinase Cs contain an amino-terminal domain similar to the C2 consensus sequence

1993 • 68 citations