“Macrophage” nitric oxide synthase is a glucocorticoid‐inhibitable primary response gene in 3T3 cells

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

1987 • 5,027 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

1992 • 1,914 citations

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

1989 • 1,850 citations

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

1991 • 1,814 citations

PRIMARY RESPONSE GENES INDUCED BY GROWTH FACTORS AND TUMOR PROMOTERS

1991 • 1,078 citations

Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform.

1992 • 1,004 citations

Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.

1992 • 877 citations

Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide.

1992 • 823 citations

Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein.

1991 • 812 citations

Steroid Receptors: Elements for Modulation of Eukaryotic Transcription

1976 • 688 citations

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

1992 • 616 citations

Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase.

1992 • 616 citations

Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase.

1992 • 498 citations

Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase.

1992 • 477 citations

Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages

1990 • 455 citations

Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene.

1992 • 412 citations

Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells.

1989 • 405 citations

Interleukin 1 and tumor necrosis factor stimulate cGMP formation in rat renal mesangial cells

1990 • 142 citations

Production of nitric oxide by murine bone marrow cells. Inverse correlation with cellular proliferation.

1992 • 119 citations

Glucocorticoids inhibit the transcriptional induction of JE, a platelet-derived growth factor-inducible gene

1991 • 63 citations

The L-Arginine Dependent Effector Mechanism Is Induced in Murine Adenocarcinoma Cells by Culture Supernatant From Cytotoxic Activated Macrophages

1988 • 63 citations

In vivo and in vitro inhibition of JE gene expression by glucocorticoids.

1991 • 59 citations

v-Src activates both protein kinase C-dependent and independent signaling pathways in murine fibroblasts.

1991 • 53 citations

A collection of mRNA species that are inducible in the RAW 264.7 mouse macrophage cell line by gamma interferon and other agents.

1992 • 48 citations

Cloning and characterization of a thermolabile v-src gene for use in reversible transformation of mammalian cells.

1992 • 33 citations

The mouse macrophage activation-associated marker protein, p71/73, is an inducible prostaglandin endoperoxide synthase (cyclooxygenase)

1993 • 32 citations

The tis Genes, Primary Response Genes Induced by Growth Factors and Tumor Promoters in 3T3 Cells

1994 • 30 citations