Molecular basis of co-operativity in protein folding

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Solvent-Accessible Surfaces of Proteins and Nucleic Acids

1983 • 2,685 citations

Analytical molecular surface calculation

1983 • 2,454 citations

Stability of Proteins Small Globular Proteins

1979 • 2,139 citations

The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure

1989 • 1,446 citations

A thermodynamic approach to the problem of stabilization of globular protein structure: A calorimetric study

1974 • 1,384 citations

Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution

1960 • 1,313 citations

Stability of Protein Structure and Hydrophobic Interaction

1988 • 1,293 citations

INTERMEDIATES IN THE FOLDING REACTIONS OF SMALL PROTEINS

1990 • 1,133 citations

Stability of proteins. Proteins which do not present a single cooperative system.

1982 • 1,041 citations

High-resolution three-dimensional structure of horse heart cytochrome c

1990 • 1,036 citations

Group contributions to the thermodynamic properties of non-ionic organic solutes in dilute aqueous solution

1981 • 971 citations

Temperature dependence of the hydrophobic interaction in protein folding.

1986 • 865 citations

Stability of Proteins

1982 • 718 citations

Structural Characterization of a Partly Folded Apomyoglobin Intermediate

1990 • 708 citations

NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A

1988 • 583 citations

Thermodynamics of Structural Stability and Cooperative Folding Behavior in Proteins

1992 • 572 citations

Protein folding: Hypotheses and experiments

1987 • 544 citations

Reexamination of the Folding of BPTI: Predominance of Native Intermediates

1991 • 505 citations

A Partial Determination by X-ray Methods, and its Correlation with Chemical Data

1961 • 486 citations

Common Features of Protein Unfolding and Dissolution of Hydrophobic Compounds

1990 • 435 citations

Cold denaturation of myoglobin

1986 • 408 citations

Sequence and structure of yeast phosphoglycerate kinase.

1982 • 364 citations

Statistical mechanical deconvolution of thermal transitions in macromolecules. I. Theory and application to homogeneous systems

1978 • 349 citations

Simulations of the Folding of a Globular Protein

1990 • 322 citations

Thermodynamic study of the apomyoglobin structure

1988 • 299 citations

Calorimetric determination of the enthalpy change for the alpha-helix to coil transition of an alanine peptide in water.

1991 • 294 citations

Molten globule intermediates and protein folding

1991 • 281 citations

Solid model compounds and the thermodynamics of protein unfolding

1991 • 272 citations

Stable submolecular folding units in a non-compact form of cytochrome c

1991 • 220 citations

α-Lactalbumin possesses a novel calcium binding loop

1986 • 216 citations

Thermodynamics of the binding of L-arabinose and of D-galactose to the L-arabinose-binding protein of Escherichia coli.

1983 • 196 citations

An equation of state describing hydrophobic interactions

1976 • 184 citations

Helix-coil stability constants for the naturally occurring amino acids in water. 22. Histidine parameters from random poly[(hydroxybutyl)glutamine-co-L-histidine]

1984 • 162 citations

Low-temperature unfolding of a mutant of phage T4 lysozyme. 2. Kinetic investigations

1989 • 161 citations

The molten globule protein conformation probed by disulphide bonds

1991 • 143 citations

Additivity relations for the heat capacities of non-electrolytes in aqueous solution

1976 • 127 citations

Use of site-directed mutagenesis to destabilize native apomyoglobin relative to folding intermediates

1989 • 124 citations

Calorimetric determination of the energetics of the molten globule intermediate in protein folding: apo-.alpha.-lactalbumin

1991 • 118 citations

Isoenthalpic and isoentropic temperatures and the thermodynamics of protein denaturation.

1991 • 114 citations

The molecular basis of cooperativity in protein folding. Thermodynamic dissection of interdomain interactions in phosphoglycerate kinase

1992 • 105 citations

Structure of the l-arabinose-binding protein from Escherichia coli at 2.4 Å resolution

1981 • 104 citations

Design and creation of a Ca2+ binding site in human lysozyme to enhance structural stability.

1989 • 98 citations

Group additivity thermodynamics for dissolution of solid cyclic dipeptides into water

1990 • 86 citations

Calorimetric investigation of lysozyme thermal denaturation

1973 • 86 citations

Heat and cold denaturation of phosphoglycerate kinase (interaction of domains)

1989 • 83 citations

Effect of metal ion binding on the secondary structure of bovine .alpha.-lactalbumin as examined by infrared spectroscopy

1991 • 70 citations

Linked thermal and solute perturbation analysis of cooperative domain interactions in proteins. Structural stability of diphtheria toxin

1990 • 62 citations

Thermodynamic investigations of proteins

1978 • 62 citations

X-ray structural evidence for a local helix-loop transition in alpha-lactalbumin.

1992 • 58 citations

Papain denaturation is not a two‐state transition

1978 • 58 citations

Thermal denaturation of staphylococcal nuclease

1985 • 57 citations

Assignment of proton NMR resonances of histidine and other aromatic residues in met-, cyano-, oxy-, and (carbon monoxy)myoglobins

1984 • 41 citations

Stability of equine lysozyme

1991 • 40 citations

Methanol-stabilized intermediates in the thermal unfolding of ribonuclease A

1982 • 40 citations

Pepsinogen denaturation is not a two‐state transition

1981 • 39 citations

CALORIMETRIC INVESTIGATION OF RIBONUCLEASE THERMAL DENATURATION

1973 • 39 citations

Thermodynamic identification of stable folding intermediates in the B-subunit of cholera toxin

1991 • 36 citations

A hierarchical “nesting” approach to describe the stability of alpha helices with side‐chain interactions

1990 • 19 citations

Intermediates in the refolding of ribonuclease at subzero temperatures. 3. Multiple folding pathways

1988 • 14 citations

Deleted Work

1955 • 0 citations