Reexamination of the Folding of BPTI: Predominance of Native Intermediates

INTERMEDIATES IN THE FOLDING REACTIONS OF SMALL PROTEINS

1990 • 1,133 citations

Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells

1989 • 884 citations

Structural characterization of folding intermediates in cytochrome c by H-exchange labelling and proton NMR

1988 • 823 citations

Structural Characterization of a Partly Folded Apomyoglobin Intermediate

1990 • 708 citations

NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A

1988 • 583 citations

Sequential resonance assignments in protein 1H nuclear magnetic resonance spectra

1982 • 562 citations

Experimental studies of protein folding and unfolding

1979 • 535 citations

Protein folding

1990 • 502 citations

Characterization of a partly folded protein by NMR methods: studies on the molten globule state of guinea pig .alpha.-lactalbumin

1989 • 473 citations

Location of disulphide bridges by diagonal paper electrophoresis. The disulphide bridges of bovine chymotrypsinogen A.

1966 • 450 citations

Kinetic role of a meta-stable native-like two-disulphide species in the folding transition of bovine pancreatic trypsin inhibitor

1984 • 308 citations

Structural description of acid-denatured cytochrome c by hydrogen exchange and 2D NMR

1990 • 306 citations

A peptide model of a protein folding intermediate

1988 • 252 citations

Hierarchic organization of domains in globular proteins

1979 • 228 citations

Detection and characterization of a folding intermediate in barnase by NMR

1990 • 212 citations

Disulfide bond formation in proteins

1984 • 189 citations

Conformational restrictions on the pathway of folding and unfolding of the pancreatic trypsin inhibitor

1977 • 188 citations

Electrostatic influence of local cysteine environments on disulfide exchange kinetics

1981 • 167 citations

Detection of an early intermediate in the folding of ribonuclease A by protection of amide protons against exchange

1979 • 154 citations

The two-disulphide intermediates and the folding pathway of reduced pancreatic trypsin inhibitor

1975 • 126 citations

Urea dependence of thiol-disulfide equilibria in thioredoxin: confirmation of the linkage relationship and a sensitive assay for structure

1989 • 115 citations

The single-disulphide intermediates in the refolding of reduced pancreatic trypsin inhibitor

1974 • 106 citations

Intermediates in the refolding of reduced pancreatic trypsin inhibitor

1974 • 97 citations

Conformations of intermediates in the folding of the pancreatic trypsin inhibitor

1987 • 96 citations

Renaturation of the reduced bovine pancreatic trypsin inhibitor

1974 • 95 citations

Role of a subdomain in the folding of bovine pancreatic trypsin inhibitor

1990 • 94 citations

Structural effects induced by removal of a disulfide-bridge: the X-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 Å

1990 • 92 citations

Energetics of folding and unfolding of pancreatic trypsin inhibitor

1977 • 89 citations

Formation of the intrachain disulfide bond in the constant fragment of the immunoglobulin light chain

1981 • 89 citations

Effects of urea and guanidine · HCl on the folding and unfolding of pancreatic trypsin inhibitor

1977 • 79 citations

Energetics of protein structure and folding

1985 • 78 citations

Characterization of protein folding intermediates

1991 • 63 citations

Multiparameter kinetic study on the unfolding and refolding of bovine carbonic anhydrase B

1980 • 55 citations

Regeneration and reduction of native bovine pancreatic ribonuclease A with oxidized and reduced dithiothreitol

1991 • 48 citations

Two‐dimensional ¹H NMR of two chemically modified analogs of the basic pancreatic trypsin inhibitor

1984 • 48 citations

Folding of RNase T1 is decelerated by a specific tertiary contact in a folding intermediate

1992 • 47 citations

On the relevance of non-random polypeptide conformations for protein folding

1988 • 42 citations

Disulfide assignments in recombinant mouse and human interleukin 4

1991 • 42 citations

The 5–55 single‐disulphide intermediate in folding of bovine pancreatic trypsin inhibitor

1991 • 38 citations

Reactivities of the cysteine residues of the reduced pancreatic trypsin inhibitor

1975 • 36 citations

Catalysis and assistance of protein folding

1991 • 32 citations

A conformational isomer of bovine pancreatic trypsin inhibitor protein produced by refolding

1980 • 30 citations

Folding and binding

1991 • 16 citations

Two types of rate-determining step in chemical and biochemical processes

1989 • 10 citations

Structural Characterization of a Partly Folded

1987 • 5 citations