A YAC contig across the fragile X site defines the region of fragility

Cloning of Large Segments of Exogenous DNA into Yeast by Means of Artificial Chromosome Vectors

1987 • 1,517 citations

A marker X chromosome.

1969 • 614 citations

Alu polymerase chain reaction: a method for rapid isolation of human-specific sequences from complex DNA sources.

1989 • 578 citations

Fragile Sites on Human Chromosomes: Demonstration of Their Dependence on the Type of Tissue Culture Medium

1977 • 524 citations

Construction and characterization of a yeast artificial chromosome library containing seven haploid human genome equivalents.

1990 • 408 citations

The marker (X) syndrome: a cytogenetic and genetic analysis

1984 • 390 citations

Physical mapping across the fragile X: Hypermethylation and clinical expression of the fragile X syndrome

1991 • 357 citations

A 3.5 genome equivalent multi access YAC library: construction, characterisation, screening and storage

1990 • 221 citations

Abnormal pattern detected in fragile-X patients by pulsed-field gel electrophoresis

1991 • 213 citations

Isolation of Sequences that Span the Fragile X and Identification of a Fragile X-Related CpG Island

1991 • 174 citations

Rapid subchromosomal localization of cosmids by nonradioactive in situ hybridization

1990 • 153 citations

The frequency of the fragile X chromosome among schoolchildren in Coventry.

1986 • 130 citations

Prevalence of the fragile‐X syndrome in mentally retarded boys in a Swedish county

1986 • 94 citations

Yeast artificial chromosome cloning of a two-megabase-size contig within chromosomal band 18q21 establishes physical linkage between BCL2 and plasminogen activator inhibitor type-2

1991 • 79 citations

Yeast artificial chromosomes containing human Xq24–Xq28 DNA: Library construction and representation of probe sequences

1990 • 64 citations

Isolation of the human chromosomal band Xq28 within somatic cell hybrids by fragile X site breakage.

1990 • 61 citations

Physical mapping of new DNA probes near the fragile X mutation (FRAXA) by using a panel of cell lines.

1990 • 60 citations

Prevalence of the fragile X syndrome in four birth cohorts of children of school age

1987 • 58 citations

In situ hybridization to cytogenetic bands of yeast artificial chromosomes covering 50% of human Xq24-Xq28 DNA.

1991 • 38 citations

Linear order of new and established DNA markers around the fragile site at Xq27.3

1991 • 26 citations