TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis

Bias in meta-analysis detected by a simple, graphical test

1997 • 47,526 citations

Meta-analysis in clinical trials

1986 • 36,193 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

2003 • 1,925 citations

p53 function and dysfunction

1992 • 1,918 citations

Meta-Analyses of Randomized Controlled Trials

1987 • 1,278 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

Role of a p53 polymorphism in the development of human papilloma-virus-associated cancer

1998 • 976 citations

Two Polymorphic Variants of Wild-Type p53 Differ Biochemically and Biologically

1999 • 712 citations

Cancer epidemiology in the last century and the next decade

2001 • 675 citations

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

2000 • 514 citations

Meta-analysis: State-of-the-Science

1992 • 504 citations

Primary structure polymorphism at amino acid residue 72 of human p53.

1987 • 466 citations

A Simple Approximation for Calculating Sample Sizes for Comparing Independent Proportions

1980 • 362 citations

p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity

2002 • 256 citations

p53 Protein accumulates frequently in early bronchial neoplasia

1994 • 211 citations

Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer

1993 • 199 citations

The p53 codon 72 polymorphism and lung cancer risk.

2000 • 190 citations

p53 codon 72 polymorphism in Taiwanese lung cancer patients: association with lung cancer susceptibility and prognosis.

1999 • 171 citations

Mutability of p53 hotspot codons to benzo(a)pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung.

2001 • 146 citations

Polymorphism at codon 213 within the p53 gene.

1991 • 137 citations

Combinations of the variant genotypes of GSTP1, GSTM1, and p53 are associated with an increased lung cancer risk.

2002 • 125 citations

P53 polymorphisms and haplotypes in lung cancer

1995 • 117 citations

Analysis of a germ line polymorphism of the p53 gene in lung cancer patients; discrete results with smoking history

1996 • 115 citations

Screening for lung cancer: The Mayo lung project revisited

1993 • 112 citations

Human lung cancer and p53 : The interplay between mutagenesis and selection

2000 • 102 citations

Association of p53 codon 72 polymorphism with advanced lung cancer: the Arg allele is preferentially retained in tumours arising in Arg/Pro germline heterozygotes

2002 • 99 citations

Determination of the allelic frequencies of an L-myc and a p53 polymorphism in human lung cancer

1994 • 93 citations

Simple sequence repeat polymorphism within the p53 gene.

1993 • 93 citations

The Li-Fraumeni syndrome: An inherited susceptibility to cancer

1997 • 84 citations

Glutathione-S-Transferase M1 and codon 72 p53 polymorphisms in a northwestern Mediterranean population and their relation to lung cancer susceptibility.

1996 • 68 citations

Measuring Effectiveness of Lung Cancer Screening

1997 • 61 citations

Relationships of TP53 codon 72 and HRAS1 polymorphisms with lung cancer risk in an ethnically diverse population.

2000 • 56 citations

Absence of Significant Germ Line p53 Mutations in Ovarian Cancer Patients

1995 • 41 citations

Biallelic Apal polymorphism of the human p53 gene (TP53)

1991 • 38 citations

Correlation of the mutation of p53 gene and the polymorphism at codon 72 in smoking-related non-small cell lung cancer patients.

1998 • 38 citations

Polymorphisms in the p53 gene in thyroid tumours and blood samples of children from areas in Belarus

1997 • 36 citations

Bst NI/Ncil polymorphism of the human p53 gene (TP53)

1991 • 30 citations

Variation in the protein coding region of the human p53 gene.

1990 • 28 citations

Identification of a polymorphism in intron 2 of the p53 gene

1994 • 25 citations

HaeIII polymorphism in intron 1 of the human p53 gene

1994 • 22 citations

New syntax and output for the meta-analysis command

1998 • 15 citations

Detection and evaluation ofp53 intron 2 polymorphism in lung carcinomas in Hong Kong

1996 • 8 citations