Probucol Suppresses Enterocytic Accumulation of Amyloid‐β Induced by Saturated Fat and Cholesterol Feeding

Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism

1998 • 1,690 citations

Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments

1992 • 883 citations

Cell Biology of the Amyloid beta-Protein Precursor and the Mechanism of Alzheimer's Disease

1994 • 749 citations

Phosphatidylinositol 3‐kinase

1994 • 649 citations

Use of Lipid-Lowering Agents, Indication Bias, and the Risk of Dementia in Community-Dwelling Elderly People

2002 • 519 citations

Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia

2009 • 252 citations

Inhibition of Intracellular Cholesterol Transport Alters Presenilin Localization and Amyloid Precursor Protein Processing in Neuronal Cells

2002 • 243 citations

IgG-Assisted Age-Dependent Clearance of Alzheimer's Amyloid β Peptide by the Blood–Brain Barrier Neonatal Fc Receptor

2005 • 225 citations

APOE genotype, cholesterol level, lipid-lowering treatment, and dementia

2005 • 217 citations

Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease

2003 • 161 citations

Apolipoprotein E, cholesterol transport and synthesis in sporadic Alzheimer's disease

2004 • 160 citations

The Choroid Plexus Removes β-Amyloid from Brain Cerebrospinal Fluid

2005 • 127 citations

Uptake of lipophilic drugs by plasma derived isolated chylomicrons: Linear correlation with intestinal lymphatic bioavailability

2005 • 125 citations

Fibrillar beta-amyloid peptide Aβ1–40 activates microglial proliferation via stimulating TNF-α release and H2O2 derived from NADPH oxidase: a cell culture study

2006 • 124 citations

Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer’s disease mouse models with abundant Aβ in plasma

2006 • 115 citations

Effects of dietary cholesterol and fatty acids on plasma cholesterol level and hepatic lipoprotein metabolism.

1990 • 95 citations

β-Amyloid or its precursor protein is found in epithelial cells of the small intestine and is stimulated by high-fat feeding

2006 • 82 citations

Effects of probucol on plasma cholesterol, high and low density lipoprotein cholesterol, and apolipoproteins A1 and A2 in adults with primary familial hypercholesterolemia

1980 • 78 citations

Post‐prandial chylomicron response may be predicted by a single measurement of plasma apolipoprotein B48 in the fasting state

1999 • 74 citations

Differential effects of dietary fatty acids on the cerebral distribution of plasma-derived apo B lipoproteins with amyloid-β

2009 • 74 citations

Apolipoprotein B immunoreactivity in senile plaque and vascular amyloids and neurofibrillary tangles in the brains of patients with Alzheimer's disease

1992 • 72 citations

The cholesterol-lowering drug Probucol increases apolipoprotein e production in the hippocampus of aged rats: implications for Alzheimer’s disease

2003 • 64 citations

The Role of Vascular Factors in Late-Onset Sporadic Alzheimers Disease. Genetic and Molecular Aspects

2009 • 63 citations

Macronutrient intake and modulation on chylomicron production and clearance

2008 • 57 citations

Effect of a statin on hepatic apolipoprotein B-100 secretion and plasma campesterol levels in the metabolic syndrome

2003 • 51 citations

Plasma lipoprotein β-amyloid in subjects with Alzheimer's disease or mild cognitive impairment

2008 • 50 citations

Physiological levels of β-amyloid peptide promote PC12 cell proliferation

1996 • 48 citations

Physiological levels of β-amyloid increase tyrosine phosphorylation and cytosolic calcium

1995 • 47 citations

Prolonged inhibition of cholesterol synthesis by atorvastatin inhibits apo B-100 and triglyceride secretion from HepG2 cells

2001 • 46 citations

Pathogenic mechanisms in Alzheimer's disease

2006 • 45 citations

The effects of fatty acids on apolipoprotein B secretion by human hepatoma cells (HEP G2)

2000 • 41 citations

Amyloid-β colocalizes with apolipoprotein B in absorptive cells of the small intestine

2009 • 40 citations

Effect of probucol on plasma clearance and organ uptake of chylomicrons and VLDLs in normal and diabetic rats.

1993 • 32 citations

Cholesterol esters regulate apoB48 secretion in CaCo2 cells

2002 • 25 citations

Mode of Action of Probucol in Reducing Serum Cholesterol in Mice

1986 • 24 citations

Synergistic effects of high fat feeding and apolipoprotein E deletion on enterocytic amyloid-beta abundance

2008 • 23 citations

Effect of probucol on plasma clearance and organ uptake of chylomicrons and VLDLs in normal and diabetic rats.

1993 • 20 citations

The effect of exogenous cholesterol and lipid-modulating agents on enterocytic amyloid-β abundance

2008 • 18 citations

Three-dimensional immunofluorescent double labelling using polyclonal antibodies derived from the same species: enterocytic colocalization of chylomicrons with Golgi apparatus

2008 • 16 citations

[Genetics of late-onset Alzheimer's disease: vascular risk and beta-amyloid metabolism].

2002 • 10 citations

Deleted Work

1955 • 0 citations