Biosynthesis of 3-Amino-5-hydroxybenzoic Acid, the Precursor of mC7N Units in Ansamycin Antibiotics

A genetic approach to the biosynthesis of the Rifamycin-chromophore in Nocardia mediterranei. IV. Identification of 3-amino-5-hydroxybenzoic acid as a direct precursor of the seven-carbon amino starter-unit.

1981 • 67 citations

3-Amino-5-hydroxybenzoic acid as a key intermediate in ansamycin and maytansinoid biosynthesis

1980 • 62 citations

Aromatic Biosynthesis. IX. The Isolation of a Precursor of Shikimic Acid¹

1953 • 60 citations

Sequencing and overexpression of the Escherichia coli aroE gene encoding shikimate dehydrogenase

1988 • 56 citations

Formation of 3-amino-5-hydroxybenzoic acid, the precursor of mC7N units in ansamycin antibiotics, by a new variant of the shikimate pathway

1992 • 55 citations

Improved Differential Spectrophotometric Determination of Rifamycins

1970 • 50 citations

Biosynthetic origin of aminobenzenoid nucleus (C7N-unit) of ansamitocin, a group of novel maytansinoid antibiotics.

1982 • 45 citations

A genetic approach to the biosynthesis of the Rifamycin-chromophore in Nocardia mediterranei. III. Isolation and identification of an early aromatic ansamycin-precursor containing the seven-carbon amino starter-unit and three initial acetate/propionate-units of the ansa chain.

1981 • 44 citations

Biosynthesis of the mitomycin antibiotics from 3-amino-5-hydroxybenzoic acid

1980 • 44 citations

Die Synthese der 5‐Dehydro‐chinasäure

1956 • 41 citations

Biosynthesis of the Ansamycin Antibiotic Ansatrienin (Mycotrienin) by Streptomyces collinus

1987 • 40 citations

Ansamycin biogenesis: Incorporation of [1‐¹³C]glucose and [1‐¹³C]glycerate into the chromophore of rifamycin S

1974 • 37 citations

Rifamycin Biosynthesis: Further Studies on Origin of the Ansa Chain and Chromophore

1974 • 35 citations

(-)-Methyl cis-3-hydroxy-4,5-oxycyclohex-1-enecarboxylate: stereospecific formation from and conversion to (-)-methyl shikimate; complex formation with bis(carbomethoxy)hydrazine

1981 • 35 citations

Synthesis and evaluation of two new inhibitors of EPSP synthase

1991 • 33 citations

3-Deoxy-D-arabino-heptulosonic acid 7-phosphate: chemical synthesis and isolation from Escherichia coli auxotrophs

1984 • 31 citations

Biosynthesis of ansatrienin. Nonincorporation of shikimic acid into the mC7N unit and stereochemistry of its conversion to the cyclohexanecarboxylic acid moiety

1987 • 28 citations

Über die Biogenese des Rifamycins S

1973 • 28 citations

Use of D-[13C6]glucose together with carbon-13-depleted glucose and homonuclear carbon-13 decoupling to identify the labeling pattern by this precursor of the "m-C7N" unit of geldanamycin

1982 • 28 citations

A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. II. Isolation and characterization of a shikimate excreting auxotrophic mutant of Nocardia mediterranei with normal rifamycin-producton.

1978 • 25 citations

Studies on the Biosynthesis of Mitomycin C by Streptomyces verticillatus

1971 • 25 citations

[40] Shikimate dehydrogenase from escherichia coli

1987 • 25 citations

Untersuchungen zur Biosynthese von Antibiotica

1989 • 24 citations

Pyruvic acid and D-glucose as precursors in mitomycin biosynthesis by Streptomyces verticillatus

1974 • 22 citations

Biosynthesis of rifamycins (ansamycins) and microbial production of shikimate pathway precursors, intermediates and metabolites.

1985 • 21 citations

Synthesis of unlabelled and carboxyl-labelled 3-Amino-5-hydroxybenzoic acid

1981 • 20 citations

Biosynthesis of the streptovaricins: 3-Amino-5-hydroxybenzoic acid as a precursor to the meta-C7N unit.

1991 • 20 citations

Biosynthetic origins of the oxygen atoms in the ansamycin antibiotics rifamycin B, O, and S

1989 • 19 citations

Biosynthesis of naphthomycin A in Streptomyces collinus

1994 • 16 citations

Role of<scp>D</scp>-[4-¹⁴C]erythrose and [3-¹⁴C]pyruvate in the biosynthesis of the meta-C–C₆–N unit of the mitomycin antibiotics in Streptomyces verticillatus

1980 • 16 citations

Synthesis of 4-amino 3,4-dideoxy-d-arabino-heptulosonic acid 7-phosphate, the biosynthetic precursor of C7N units in ansamycin antibiotics

1994 • 15 citations

Study to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei.

1990 • 14 citations

[39] Dehydroquinate synthase from escherichia coli, and its substrate 3-deoxy-d-arabino-heptulosonic acid 7-phosphate

1987 • 13 citations

Microdegradation Procedure for Radioactive Peptide Ergot Alkaloids

1971 • 5 citations

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