Immunocytochemical study of the distribution of the free radical scavenging enzymes CU/ZN superoxide dismutase (SOD1); MN superoxide dismutase (MN SOD) and catalase in the normal human spinal cord and in motor neuron disease

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Superoxide Dismutase

1969 • 12,578 citations

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1993 • 6,762 citations

Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation

1994 • 3,959 citations

Reactive Oxygen Species and the Central Nervous System

1992 • 2,931 citations

Importance of SE-glutathione peroxidase, catalase, and CU/ZN-SOD for cell survival against oxidative stress

1994 • 1,178 citations

Oxidative processes and antioxidative defense mechanisms in the aging brain ¹

1995 • 810 citations

Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis.

1995 • 694 citations

Superoxide Dismutase Activity, Oxidative Damage, and Mitochondrial Energy Metabolism in Familial and Sporadic Amyotrophic Lateral Sclerosis

1993 • 627 citations

Oxygen free radicals and human disease

1995 • 378 citations

Amyotrophic lateral sclerosis: Recent insights from genetics and transgenic mice

1995 • 353 citations

Oxidative damage to protein in sporadic motor neuron disease spinal cord

1995 • 326 citations

Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons.

1995 • 313 citations

Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons.

1994 • 291 citations

Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells.

1994 • 271 citations

Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis

1995 • 266 citations

Randomized, Double-Blind, Controlled Trial of Acetylcysteine in Amyotrophic Lateral Sclerosis

1995 • 180 citations

Immunocytochemical localization of catalase in the central nervous system of the rat.

1995 • 104 citations

An immunohistochemical study of copper/zinc superoxide dismutase and manganese superoxide dismutase in rat hippocampus after transient cerebral ischemia

1993 • 100 citations

Iron, selenium and glutathione peroxidase activity are elevated in sporadic motor neuron disease

1994 • 98 citations

Metals in spinal cord tissue of patients dying of motor neuron disease

1979 • 89 citations

Response of Human Endothelial Cell Antioxidant Enzymes to Hyperoxia

1992 • 81 citations

Analysis of the functional effects of a mutation in SOD1 associated with familial amyotrophic lateral sclerosis

1994 • 70 citations

Distribution of manganese-dependent superoxide dismutase in the human brain

1994 • 65 citations

Metallothionein in Amyotrophic Lateral Sclerosis

1994 • 56 citations

IMMUNOHISTOCHEMICAL DEMONSTRATION OF Cu/Zn SUPEROXIDE DISMUTASE IN THE SPINAL CORD OF PATIENTS WITH FAMILIAL AMYOTRO-PHIC LATERAL SCLEROSIS

1993 • 51 citations

Copper/zinc superoxide dismutase mRNA levels are increased in sporadic amyotrophic lateral sclerosis motorneurons

1994 • 42 citations

Immunohistochemical expression of peroxisomal enzymes in developing human brain

1993 • 37 citations

Neutron Activation Analysis of Trace Elements in Motor Neuron Disease Spinal Cord

1995 • 33 citations

Decrease in and Mn-superoxide dismutase activities in brain and spinal cord of patients with amyotrophic lateral sclerosis

1994 • 25 citations

An immunohistochemical study of the neuronal expression of manganese superoxide dismutase in sporadic amyotrophic lateral sclerosis

1994 • 19 citations