Hotspots of GPI-anchored proteins and integrin nanoclusters function as nucleation sites for cell adhesion

Functional rafts in cell membranes

1997 • 9,471 citations

Far-Field Optical Nanoscopy

2007 • 2,876 citations

Precise Nanometer Localization Analysis for Individual Fluorescent Probes

2002 • 2,262 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

Structural Basis of Integrin Regulation and Signaling

2007 • 1,575 citations

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

2008 • 1,461 citations

Paradigm Shift of the Plasma Membrane Concept from the Two-Dimensional Continuum Fluid to the Partitioned Fluid: High-Speed Single-Molecule Tracking of Membrane Molecules

2005 • 1,086 citations

Lipid rafts: at a crossroad between cell biology and physics

2007 • 1,072 citations

Nanoscale Organization of Multiple GPI-Anchored Proteins in Living Cell Membranes

2004 • 865 citations

Single-Molecule Microscopy Reveals Plasma Membrane Microdomains Created by Protein-Protein Networks that Exclude or Trap Signaling Molecules in T Cells

2005 • 748 citations

Integrins Regulate Rac Targeting by Internalization of Membrane Domains

2004 • 533 citations

Revisiting the Fluid Mosaic Model of Membranes

1995 • 457 citations

Nanoclusters of GPI-Anchored Proteins Are Formed by Cortical Actin-Driven Activity

2008 • 434 citations

Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines

2005 • 405 citations

Far-Field Optical Nanoscopy

2009 • 372 citations

Functionally different GPI proteins are organized in different domains on the neuronal surface

1999 • 363 citations

The involvement of lipid rafts in the regulation of integrin function

2002 • 302 citations

Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation

2008 • 298 citations

GPI-anchored receptor clusters transiently recruit Lyn and Gα for temporary cluster immobilization and Lyn activation: single-molecule tracking study 1

2007 • 296 citations

Force as a Facilitator of Integrin Conformational Changes during Leukocyte Arrest on Blood Vessels and Antigen-Presenting Cells

2007 • 276 citations

Dynamics in the plasma membrane: how to combine fluidity and order

2006 • 274 citations

Lipid rafts: now you see them, now you don't

2006 • 235 citations

Cell biology beyond the diffraction limit: near-field scanning optical microscopy

2001 • 205 citations

Tether and trap: regulation of membrane-raft dynamics by actin-binding proteins

2007 • 178 citations

Integrin Leukocyte Function-associated Antigen-1-mediated Cell Binding Can Be Activated by Clustering of Membrane Rafts

1999 • 178 citations

Cytoskeletal Regulation Couples LFA-1 Conformational Changes to Receptor Lateral Mobility and Clustering

2006 • 136 citations

Organization of the Integrin LFA-1 in Nanoclusters Regulates Its Activity

2006 • 126 citations

Dynamic Partitioning into Lipid Rafts Controls the Endo-Exocytic Cycle of the αL/β₂Integrin, LFA-1, during Leukocyte Chemotaxis

2005 • 121 citations

Near‐field scanning optical microscopy in liquid for high resolution single molecule detection on dendritic cells

2004 • 114 citations

Imaging nanometer domains of β-adrenergic receptor complexes on the surface of cardiac myocytes

2005 • 101 citations

Nanoscale Organization of the Pathogen Receptor DC‐SIGN Mapped by Single‐Molecule High‐Resolution Fluorescence Microscopy

2007 • 90 citations

Monomer–dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assemblies

2007 • 80 citations

Nanometer-scale organization of the alpha subunits of the receptors for IL2 and IL15 in human T lymphoma cells

2008 • 62 citations

Dynamic Re‐organization of Individual Adhesion Nanoclusters in Living Cells by Ligand‐Patterned Surfaces

2009 • 14 citations