Evidence for autocrine activation of a tyrosine kinase in a human gastric carcinoma cell line

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

Autocrine Secretion and Malignant Transformation of Cells

1980 • 1,370 citations

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1985 • 1,360 citations

A thousand and one protein kinases

1987 • 1,066 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1986 • 795 citations

A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family

1986 • 647 citations

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors.

1987 • 567 citations

Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: Implications for autocrine receptor activation

1984 • 238 citations

Evidence for the platelet-derived growth factor-stimulated tyrosine phosphorylation of the platelet-derived growth factor receptor in vivo. Immunopurification using a monoclonal antibody to phosphotyrosine.

1984 • 209 citations

Phosphotyrosine-containing proteins isolated by affinity chromatography with antibodies to a synthetic hapten

1981 • 203 citations

Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes.

1987 • 202 citations

Blockade of autocrine stimulation in simian sarcoma virus-transformed cells reverses down-regulation of platelet-derived growth factor receptors.

1984 • 163 citations

An angiogenic growth factor is expressed in human glioma cells.

1987 • 152 citations

Detection of phosphotyrosine-containing proteins in the detergent-insoluble fraction of RSV-transformed fibroblasts by azobenzene phosphonate antibodies.

1984 • 147 citations

Evidence That the v- sis Gene Product Transforms by Interaction with the Receptor for Platelet-Derived Growth Factor

1985 • 138 citations

Signal Transduction in Human T Lymphocytes

1987 • 89 citations

p145, a Protein with Associated Tyrosine Kinase Activity in a Human Gastric Carcinoma Cell Line

1988 • 81 citations

Tumor promoter and epidermal growth factor stimulate phosphorylation of the c-erbB-2 gene product in MKN-7 human adenocarcinoma cells.

1988 • 80 citations

Receptor for bombesin with associated tyrosine kinase activity.

1986 • 77 citations

In vivo phosphorylation and dephosphorylation of the platelet-derived growth factor receptor studied by immunoblot analysis with phosphotyrosine antibodies

1986 • 52 citations

Kinetics and regulation of the tyrosine phosphorylation of epidermal growth factor receptor in intact A431 cells.

1988 • 51 citations

Molecular Characterization of the Human trk Oncogene

1986 • 50 citations

p145, a protein with associated tyrosine kinase activity in a human gastric carcinoma cell line.

1988 • 49 citations

Activation of the protein-tyrosine kinase associated with the bombesin receptor complex in small cell lung carcinomas.

1988 • 39 citations

Immunological detection of proteins phosphorylated at tyrosine in cells stimulated by growth factors or transformed by retroviral-oncogene-coded tyrosine kinases

1986 • 34 citations

A Mr=190,000 glycoprotein phosphorylated on tyrosine residues in epidermal growth factor stimulated KB cells is the product of the C-erbB-2 gene

1987 • 33 citations

Proteins phosphorylated on tyrosine as markers of human tumor cell lines

1987 • 18 citations