Transcriptional regulatory regions for expression of the rat pyruvate kinase M gene

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Chapter 4 Preparation of Isolated Rat Liver Cells

1976 • 5,335 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

Purification and Biochemical Characterization of the Promoter-Specific Transcription Factor, Sp1

1986 • 1,473 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

NUCLEASE HYPERSENSITIVE SITES IN CHROMATIN

1988 • 1,233 citations

The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing.

1986 • 517 citations

Imaging plate illuminates many fields

1988 • 495 citations

Crystallization, Characterization and Metabolic Regulation of Two Types of Pyruvate Kinase Isolated from Rat Tissues*

1967 • 456 citations

A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene.

1990 • 376 citations

Multimolecular Forms of Pyruvate Kinase from Rat and Other Mammalian Tissues*

1972 • 359 citations

The L- and R-type isozymes of rat pyruvate kinase are produced from a single gene by use of different promoters.

1987 • 332 citations

Characterization of a Dimerization Motif in AP-2 and Its Function in Heterologous DNA-Binding Proteins

1991 • 234 citations

Isolation of human cDNA clones ofmyb-related genes, A-myband B-myb

1988 • 222 citations

Down-regulation of c-myb gene expression is a prerequisite for erythropoietin-induced erythroid differentiation.

1988 • 186 citations

A method for increasing the sensitivity of chloramphenicol acetyltransferase assays in extracts of transfected cultured cells

1987 • 161 citations

Trans-activation by the c-mybproto-oncogene

1989 • 126 citations

c-myb transactivates cdc2 expression via Myb binding sites in the 5'-flanking region of the human cdc2 gene.

1993 • 125 citations

Regulation of a collagen gene promoter by the product of viral mos oncogene

1985 • 115 citations

Advantages of firefly luciferase as a reporter gene: Application to the interleukin-2 gene promoter

1989 • 112 citations

Nuclear Proteins That Bind the Human ϒ-Globin Gene Promoter: Alterations in Binding Produced by Point Mutations Associated with Hereditary Persistence of Fetal Hemoglobin

1988 • 112 citations

Nucleotide preferences in sequence-specific recognition of DNA by c-mybprotein

1991 • 109 citations

DNA binding activity and transcriptional activator function of the human B-myb protein compared with c-MYB.

1990 • 105 citations

Strontium phosphate transfection of human cells in primary culture: stable expression of the simian virus 40 large-T-antigen gene in primary human bronchial epithelial cells.

1987 • 101 citations

Electrophoretic and Kinetic Studies of Mutant Erythrocyte Pyruvate Kinases

1974 • 94 citations

Isolation and characterization of the human pyruvate kinase M gene

1991 • 88 citations

Rat pyruvate kinase M gene

1989 • 72 citations

Nuclear proteins that bind the human gamma-globin gene promoter: alterations in binding produced by point mutations associated with hereditary persistence of fetal hemoglobin.

1988 • 58 citations

Cell cycle-associated expression of M2-type isozyme of pyruvate kinase in proliferating rat thymocytes.

1992 • 53 citations

Identification and characterization of hepatocyte-specific regulatory regions of the rat pyruvate kinase L gene. The synergistic effect of multiple elements.

1990 • 48 citations

DNase I- and micrococcal nuclease-hypersensitive sites in the human apolipoprotein B gene are tissue specific.

1988 • 46 citations

Expression of liver type pyruvate kinase in insulinoma cells: Involvement of LF-B1 (HNF1)

1991 • 36 citations

Hybrid isozymes of rat pyruvate kinase. Their subunit structure and developmental changes in the liver

1978 • 30 citations

Isozyme patterns of pyruvate kinase in various primary liver tumors induced during the process of hepatocarcinogenesis.

1974 • 29 citations

Cell type-specific interactions of transcription factors with a housekeeping promoterin vivo

1993 • 23 citations

Molecular cloning of cDNA sequences for rat M2-type pyruvate kinase and regulation of its mRNA.

1984 • 20 citations

Pyruvate kinase isoenzyme transitions in cultures of fetal rat hepatocytes

1988 • 6 citations