Differential Role of Lymphocyte Function-Associated Antigens in the Activation of Nickel-Specific Peripheral Blood T Lymphocytes

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration

1968 • 2,659 citations

The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion Receptors of the Immune System

1987 • 1,104 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1

1989 • 837 citations

The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions.

1983 • 583 citations

Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal inflamed skin: Modulation by recombinant gamma interferon and tumor necrosis factor

1989 • 505 citations

The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester.

1986 • 487 citations

Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

1989 • 482 citations

The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3

1987 • 453 citations

Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones

1986 • 437 citations

Regulated expression of Mg2+ binding epitope on leukocyte integrin alpha subunits.

1989 • 321 citations

The CD2-LFA-3 and LFA-1-ICAM pathways: relevance to T-cell recognition

1989 • 269 citations

A monoclonal antibody (NKI-L16) directed against a unique epitope on the alpha-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions.

1988 • 248 citations

Dermo-Epidermal Separation with Suction

1967 • 248 citations

Isolated human follicular dendritic cells display a unique antigenic phenotype.

1989 • 225 citations

Regulatory properties of LFA-1 α and β chains in human T-lymphocyte activation

1988 • 225 citations

The Role of Adhesion Molecules, Chemotactic Factors, and Cytokines in Inflammatory and Neoplastic Skin Disease—1990 Update

1990 • 214 citations

Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens.

1987 • 213 citations

On the mode of action of LFA-1

1990 • 208 citations

Isolation and characterization of human tonsil dendritic cells.

1988 • 201 citations

Kinetics and characterization of intercellular adhesion molecule-1 (ICAM-1) expression on keratinocytes in various inflammatory skin lesions and malignant cutaneous lymphomas

1989 • 197 citations

Induction and regulation of contact hypersensitivity by resident, bone marrow-derived, dendritic epidermal cells: Langerhans cells and Thy-1+ epidermal cells.

1986 • 174 citations

Heterogeneous distribution and transmembrane signaling properties of lymphocyte function-associated antigen (LFA-1) in human lymphocyte subsets.

1989 • 158 citations

The role of CD4 in T-cell activation: accessory molecule or co-receptor?

1989 • 134 citations

Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes.

1987 • 129 citations

The lymphocyte function-associated antigen (LFA)-1 and CD2/LFA-3 pathways of antigen-independent human T cell adhesion.

1987 • 112 citations

Intercellular Adhesion Molecule Expression in the Evolving Human Cutaneous Delayed Hypersensitivity Reaction

1989 • 106 citations

Quantitation of Surface Antigens on Cultured Murine Epidermal Langerhans Cells: Rapid and Selective Increase in the Level of Surface MHC Products

1988 • 103 citations

Nickel‐specific T lymphocyte clones derived from allergic nickel‐contact dermatitis lesions in man: heterogeneity based on requirement of dendritic antigen‐presenting cell subsets

1987 • 88 citations

Adhesion Molecules on the Plasma Membrane of Epidermal Cells. I. Human Resting Langerhans Cells Express Two Members of the Adherence-promoting CD11/CD18 Family, Namely, H-Mac-1 (CD11b/CD18) and gp 150,95 (CD11c/CD18)

1989 • 67 citations

A monoclonal antibody against altered LFA‐1 induces proliferation and lymphokine release of cloned T cells

1986 • 57 citations

Dendritic Cells and Monocytes as Accessory Cells in T‐Cell Responses in Man

1985 • 55 citations

Direct and indirect nickel‐specific stimulation of T lymphocytes from patients with allergic contact dermatitis to nickel

1988 • 49 citations

The role of intercellular adhesion molecules in inflammatory skin reactions

1988 • 48 citations

Immunological marker analysis of cells in the various hematopoietic differentiation stages and their malignant counterparts.

1987 • 44 citations

Lymphocyte Transformation in Nickel Allergy: Amplification of T‐lymphocyte Responses to Nickel Sulphate by Macrophages in Vitro

1980 • 35 citations

The mixed epidermal cell-lymphocyte reaction. I. Human epidermal cells elicit a greater allogeneic lymphocyte response than do autologous peripheral blood lymphoid cells.

1983 • 33 citations

The requirement for surface Ig signaling as a prerequisite for T cell:B cell interactions. A possible role for desialylation.

1988 • 29 citations

The Sensitization Phase of T‐Cell‐Mediated Immunitya

1988 • 24 citations

Conditions enhancing the percentage and size of E rosettes formed by T lymphocytes

1978 • 22 citations

The restrictive role of sialic acid in antigen presentation to a subset of human peripheral cd4⁺ t lymphocytes that requires antigen‐presenting dendritic cells

1989 • 20 citations

Studies on the Role of Lymphocyte Function‐Associated Antigen 1 (LFA‐1) in T Cell Activation

1988 • 19 citations

Analysis of the role of leukocyte function-associated antigen-1 in activation of human influenza virus-specific T cell clones.

1990 • 18 citations

Quantification of patch test reactions by transcutaneous PO₂ measurement

1987 • 13 citations

Involvement of “accessory” and antigen receptor molecules in human helper T cell clone activation studied by monoclonal antibody inhibition

1989 • 3 citations

In Vitro Nickel-Specific T-Lymphocyte Proliferation: Methodological Aspects

1989 • 2 citations

Physical Interaction Between Dendritic Cells and Lymphocytes is not LFA-1 Mediated

1988 • 1 citations

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